2. Bay Area Regional Center California State University, East Bay Biomedical Sciences Oscar Wambuguh (Affiliate Director) Debapriya Sengupta (Affiliate Assistant)

3. Prepare students for high demand, high pay careers. Prepare students for rigorous post-secondary education and training. Address impending critical shortage of qualified science and health professionals. Biomedical Sciences Program Goals:

4. Biomedical Careers – some examples Physician Nurse Dentist Veterinarian Pharmacist Physical Therapist Dietician Surgeon Optometrist Research Scientist Health Information Manager Medical Technologist Radiology Technician Medical Technical Writer Physician Assistant Biomedical Engineer Sonographer Occupational Therapist Health Inspector

5. High School Program Biomedical Science Four Course sequence Principles of the Biomedical Sciences Human Body Systems Medical Interventions Biomedical Innovation/Capstone Course

6. Course #1:Principles of the Biomedical Sciences (PBS)  The study of human medicine, research processes & an introduction to bioinformatics.  Investigation of the human body systems and various health conditions including: heart disease, diabetes, sickle-cell disease, hyper-cholesterolemia, and infectious diseases.

7. PBS Topics:  Literary research skills  Human body systems  Basic chemistry  Structure and function of DNA  Bioinformatics  Protein structure  Causes of infectious diseases  Grant proposals

8. PBS Activity Example from Unit 4 in the PBS curriculum: Students learn about chromosomes and DNA by making a chromosome spread so they can observe chromosomes in a cell

9. Example from Unit 4 in the PBS curriculum: students use a computer simulation to view how protein shape is affected by its environment and by its component parts PBS Activity

10. Course #2: Human Body Systems (HBS)  Study of basic human physiology, especially in relationship to human health.  Central theme: how the body systems work together to maintain internal balance & good health.  Students use data acquisition software to monitor body functions & use the Anatomy with Clay® Manikens™ to study body structure.

11.  Relationship between structure and function  Maintenance of health  Defense against disease  Communication within the body and with the outside world  Movement of the body and of substances around the body  Energy distribution and processing HBS Topics:

12. HBS Activity Example from HBS curriculum: This is the Maniken from Anatomy in Clay used throughout the Human Body Systems course for students to build body systems and parts using clay

13. Example from Unit 1 in the HBS curriculum: Students take measurements of bones to determine if a bone is from a man or a woman and to determine that person’s ethnicity. HBS Activity

14. Course #3: Medical Interventions (MI)  Investigation of various medical interventions that extend and improve the quality of life including: diagnostics, surgery, bio- nanotechnology, pharmacology, prosthetics, rehabilitation, & life style choices.

15. Medical Interventions Students investigate the variety of interventions involved in the prevention, diagnosis and treatment of disease as they follow the lives of a fictitious family.

16. MI Activity Example from Unit 4. Students build and use a mock laparoscopic surgery trainer box.

17.  Molecular biology & genetic engineering  Design process for pharmaceuticals and medical devices  Medical imaging, including x-rays, CT scans, & MRI scans  Disease detection & prevention  Rehabilitation after disease or injury  Medical interventions of the future MI Topics:

18. Course #4: Biomedical Innovation  Capstone Course: students will apply their knowledge and skills to solve problems related to the biomedical sciences  They may work with a mentor or advisor from a university, hospital, physician’s office, or industry as they complete their research and problem-solution process.  Students will present their findings and results in a symposium style format to an audience which may include representatives from the local healthcare or business community or the school’s PLTW® partnership team

19. Biomedical Innovation Course Benefits:  Progressively challenging problems  Flexible design  Apply knowledge and skills learned in all previous courses  Multiple presentations  Design innovative solutions for the health challenges of the 21st century  Opportunity to work with mentor(s)

20. BI Topics  Design of Effective Emergency Room  Exploring Human Physiology  Design of a Medical Innovation  Investigating Water Contamination  Combating a Public Health Issue  Molecular Biology in Action (Optional)  Forensic Autopsy (Optional)  Independent Project (Optional)

21. Total Typical BMS Cost - First 3 Courses Typical Non-Recurring (includes initial training for one teacher for three courses but excludes computers and facilities that most schools already have): $56,000 Typical Annual Recurring (includes typical Professional Development for replacement teachers, program fees, LabVIEW software and consumables): $7,000

22. Student College Credit http://clep.collegeboard.org/exam/biology/questions Students must pass this test with a score of 50 to get 4 units credit for GE in Biology 1001 Teacher CEU Credit Teachers who complete CT with us can apply for 9 CEU units per course after completing an additional assignment (Cost: $801)