What we will review this lecture:

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Presentation transcript:

What we will review this lecture: Basic elements of cell signalling Autocrine, paracrine, endocrine, synaptic Types of ligands The three basic types of cell surface receptors Signalling through G-protein coupled receptors Signalling through enzyme-linked receptors Source for additional reading: Chapter 15 of Molecular Biology of the Cell, 4th edition

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Ijsbrand Kramer/Licensed through the Higher Education Academy/JISC MediaHub

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Ijsbrand Kramer/Licensed through the Higher Education Academy/JISC MediaHub

Ijsbrand Kramer/Licensed through the Higher Education Academy/JISC MediaHub

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Molecular Biology of the Cell. 4th edition Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science.

Ijsbrand Kramer/Licensed through the Higher Education Academy/JISC MediaHub

Friedrich Grimminger, Ralph T. Schermuly & Hossein A. Ghofrani Friedrich Grimminger, Ralph T. Schermuly & Hossein A. Ghofrani. Nature Reviews Drug Discovery 9, 956-970

Friedrich Grimminger, Ralph T. Schermuly & Hossein A. Ghofrani Friedrich Grimminger, Ralph T. Schermuly & Hossein A. Ghofrani. Nature Reviews Drug Discovery 9, 956-970

Ijsbrand Kramer/Licensed through the Higher Education Academy/JISC MediaHub

Laura R. Pearce, David Komander & Dario R. Alessi Laura R. Pearce, David Komander & Dario R. Alessi. Nature Reviews Molecular Cell Biology 11, 9-22

Laura R. Pearce, David Komander & Dario R. Alessi Laura R. Pearce, David Komander & Dario R. Alessi. Nature Reviews Molecular Cell Biology 11, 9-22