Fig. 12-1

Fig µm200 µm 20 µm (a) Reproduction (b) Growth and development (c) Tissue renewal

Fig. 12-2a 100 µm (a) Reproduction

Fig. 12-2b 200 µm (b) Growth and development

Fig. 12-2c 20 µm (c) Tissue renewal

Fig µm

Fig µmChromosomes Chromosome duplication (including DNA synthesis) Chromo- some arm Centromere Sister chromatids DNA molecules Separation of sister chromatids Centromere Sister chromatids

Fig S (DNA synthesis) MITOTIC (M) PHASE Mitosis Cytokinesis G1G1 G2G2

Fig G 2 of Interphase Centrosomes (with centriole pairs) Chromatin (duplicated) Nucleolus Nuclear envelope Plasma membrane Early mitotic spindle Aster Centromere Chromosome, consisting of two sister chromatids Prophase Prometaphase Fragments of nuclear envelope Nonkinetochore microtubules Kinetochore microtubule Metaphase plate Spindle Centrosome at one spindle pole Anaphase Daughter chromosomes Telophase and Cytokinesis Cleavage furrow Nucleolus forming Nuclear envelope forming

Prophase Fig. 12-6a Prometaphase G 2 of Interphase

Fig. 12-6b PrometaphaseProphase G 2 of Interphase Nonkinetochore microtubules Fragments of nuclear envelope Aster Centromere Early mitotic spindle Chromatin (duplicated) Centrosomes (with centriole pairs) Nucleolus Nuclear envelope Plasma membrane Chromosome, consisting of two sister chromatids Kinetochore microtubule

Fig. 12-6c MetaphaseAnaphase Telophase and Cytokinesis

Fig. 12-6d MetaphaseAnaphase Telophase and Cytokinesis Cleavage furrow Nucleolus forming Metaphase plate Centrosome at one spindle pole Spindle Daughter chromosomes Nuclear envelope forming

Fig Microtubules Chromosomes Sister chromatids Aster Metaphase plate Centrosome Kineto- chores Kinetochore microtubules Overlapping nonkinetochore microtubules Centrosome 1 µm 0.5 µm

Cleavage furrow Fig. 12-9a 100 µm Daughter cells (a) Cleavage of an animal cell (SEM) Contractile ring of microfilaments

Fig. 12-9b Daughter cells (b) Cell plate formation in a plant cell (TEM) Vesicles forming cell plate Wall of parent cell New cell wallCell plate 1 µm

Fig Chromatin condensing Metaphase AnaphaseTelophase Prometaphase Nucleus Prophase Nucleolus Chromosomes Cell plate 10 µm

Fig a Nucleus Prophase 1 Nucleolus Chromatin condensing

Fig b Prometaphase 2 Chromosomes

Fig c Metaphase 3

Fig d Anaphase 4

Fig e Telophase 5 Cell plate 10 µm

Fig. 12-UN2

Fig Origin of replication Two copies of origin E. coli cell Bacterial chromosome Plasma membrane Cell wall

Fig Origin of replication Two copies of origin E. coli cell Bacterial chromosome Plasma membrane Cell wall Origin

Fig Origin of replication Two copies of origin E. coli cell Bacterial chromosome Plasma membrane Cell wall Origin

Fig Origin of replication Two copies of origin E. coli cell Bacterial chromosome Plasma membrane Cell wall Origin

Fig (a) Bacteria Bacterial chromosome Chromosomes Microtubules Intact nuclear envelope (b) Dinoflagellates Kinetochore microtubule Intact nuclear envelope (c) Diatoms and yeasts Kinetochore microtubule Fragments of nuclear envelope (d) Most eukaryotes

Fig Tumor A tumor grows from a single cancer cell. Glandular tissue Lymph vessel Blood vessel Metastatic tumor Cancer cell Cancer cells invade neigh- boring tissue. Cancer cells spread to other parts of the body. Cancer cells may survive and establish a new tumor in another part of the body

Fig. 12-UN1 Telophase and Cytokinesis Anaphase Metaphase Prometaphase Prophase MITOTIC (M) PHASE Cytokinesis Mitosis S G1G1 G2G2