Bio 449Lecture 13 - Endocrinology ISep. 29, 2010 Chemical messengers Classification of messengers Distance of travel Chemical structure Secreting tissue Hormone receptors Control of hormone release Hypothalamic-pituitary system Structure Hormones Poterior pituitary Anterior pituitary Hypothalamus Feedback control Terms to Know Exocrine gland Endocrine gland Hormone Paracrine agent Autocrine agent Cytokine Peptide hormone Steroid hormone Amine Eicosanoid Prostaglandin Glandular hormone Neurohormone Neurosecretory cells Prohormone Tropic hormone Readings Lectures 10-12:Chapter 10, pages Lectures 13-14:Chapters 6 & 7

Bio 449Lecture 13 - Endocrinology ISep. 29, 2010 More Terms Anterior pituitary Posterior pituitary Follicle-stimulating hormone (FSH) Luteinizing hormone (LH) Growth hormone (GH) Thyroid-stimulating hormone (TSH) Adrenocorticotropic hormone (ACTH) Prolactin (PRL) Gonadotropin releasing hormone (GnRH) Growth hormone releasing hormone (GHRH) Thyrotropin releasing hormone (TRH) Corticotropin releasing hormone (CRH) Prolactin releasing hormone (PRH) aka Prolactin Releasing Factors (PRF) Growth hormone inhibiting hormone (GHIH) Prolactin inhibiting hormone (PIH, aka dopamine) Oxytocin (OT) Antidiuretic hormone (ADH, aka vasopressin)

Types of glands

Chemical messengers Classification of messengers

Neurotransmitter Fig. 6-2

Distance of travel

Autocrine and paracrine agents Fig. 6-1

Hormone Fig. 6-2

Chemical structure

Secreting tissue

Neurohormone Fig. 6-2

Chemical messengers Hormone receptors

Membrane-bound receptors Fig. 6-5

Intracellular receptors Fig. 6-4

Control of hormone release

Hypothalamic-pituitary system

Hypothalamus and pituitary Fig.7-11

Posterior pituitary Fig.7-12 HYPOTHALAMUS Vein POSTERIOR PITUITARY

Anterior pituitary Fig.7-12 Endocrine cells Neurons Portal vessels HYPOTHALAMUS Veins Artery ANTERIOR PITUITARY POSTERIOR PITUITARY Capillary bed TO TARGET ORGANS

Hypothalamic-pituitary system Hormonal pathways

Hypothalamic-pituitary system Feedback control