DIABETES MELITUS, HYPERTENSION AND PARKINSON DISEASE IN A COMMON THREE LEAF CLOVER NEURODEGENERATIVE PATHWAY Grigorios G. Dimas 1, Charikleia T. Sachinidou.

Slides:

Advertisements

Similar presentations

بسم الله الرحمن الرحيم. Immunological markers in the pathogenesis of type 1 diabetes in Saudi children.

Advertisements

The FREEDOM Study (Impact of Short Daily Hemodialysis on Restless Legs Symptoms and Sleep Disturbances) Source Jaber BL, Schiller B, Burkart JM, et al.

REACH Healthcare Foundation Prepared by Mid-America Regional Council 2013 Kansas City Regional Health Assessment.

Project Partners: 計劃夥伴： Funded by: 捐助機構： Gap of Health Care for Midlife Women: Controlling Risk Factors of Stroke as Example Chau Pui Hing CADENZA Project,

G.N. Dalekos3, M. Elisaf2, A.I. Hatzitolios1

Diabetic Dermopathy Thomas Repas D.O. Diabetes, Endocrinology and Nutrition Center, Affinity Medical Group, Neenah, Wisconsin Member, Inpatient Diabetes.

PREVALENCE AND PREDICTORS OF POTENTIALLY INAPPROPRIATE MEDICATION USE IN ELDERLY PATIENTS IN TWO INDIAN TEACHING HOSPITALS PARTHASARATHI G, HARUGERI A,

“ Age-Related Differences in Characteristics, Performance Measures, Treatment Trends, and Outcomes in Patients with Ischemic Stroke ” Gregg C. Fonarow,

Parkinson’s Disease Shirley H. Wray, M.D., Ph.D., Professor of Neurology, Harvard Medical School Director, Unit for Neurovisual Disorders Massachusetts.

Grigorios G. Dimas1, Thomas J. Tegos2, Fotios S. Iliadis1, Ilias E

Dementia. Definition Loss of function in multiple cognitive abilities Assuming the individual had normal abilities before the onset Many of the 70 recognized.

Includes adults >65 years old Fastest growing population in US and in the majority of developed nations. 20% of hospitalizations for those >65 are due.

Parkinson’s Disease and Treatment Shalla Hanson Medicinal Chemistry April 2009.

IDF-EMME Region Meeting September 7-9, 2007 Cairo, Egypt.

931-4 Convergence Insufficiency. History A 73-year old man with known PD for 10 years, complained of horizontal double vision for 18 months. He could.

Consultants: Jillian Lyon and Mary Ehlers The Impact of Atypical Antipsychotic Use on Obstructive Sleep Apnea.

Pattern of Diabetes Emergencies among adult Yemeni Diabetic Patients Dr. Zayed Atef Faculty of Medicine Sana’a University.

Effect of Hypertension and Dyslipidemia on glycemic control among Type 2 Diabetes patients in Thailand Dr. Mya Thandar Dr.PH. Batch 5 1.

Presented by Dr. Soe Sandi Tint

INTRODUCTION Dysregulation of Hypothalamic-Pituitary-Adrenal, (HPA), axis has been hypothesized to participate in the emergence of psychosis, yet findings.

Conclusion In conclusion, preliminary data from this nutrition intervention study suggest that a well balanced Mediterranean-type diet is able to reduce.

SLEEP DISORDERS IN ELDERLY RURAL POPULATION OF FASRALA (CENTRAL GREECE) Nikolaos Vaitsis 1, Matina Aggelakou-Vaitsi 1, Irene Anastassopoulou 2 1 Private.

Parkinson’s Disease storyboard. Possible Intro Scenario As an resident at Normal Hospital, you are beginning your rotation in neurology. Your supervisor,

Intranasal Delivery of Proteins Using Cationic Liposomes for the Treatment of Parkinson’s Disease and the Use of Bioquant ® Image Analysis Software Presented.

INTRODUCTION The stress diathesis hypothesis of psychosis is one of the most prevailing models of the aetiopathology of psychotic disorders. Cortisol is.

INCREASED CIRCULATING SERUM LEVELS OF MMP-9 AND VEGF-A ARE ASSOCIATED WITH OXIDATIVE STRESS IN PATIENTS WITH PRIMARY GLOMERULONEPHRITIS AND EARLY STAGES.

Deploying Care Coordination and Care Transitions – Colorado June 2015.

Comorbidities and Diabetes Care – Impact on Treatment Strategies Dr. Joel Rodriguez-Saldana Multidisciplinary Diabetes Centres Mexico.

Effect of Hypertension and Dyslipidemia on glycemic control among Type 2 Diabetes patients Dr. Mya Thandar.

Al wakeel J, Bayoumi M, Al Ghonaim M, Al Harbi A, Al Swaida A, Mashraqy A.

ASSOCIATION OF CIRCULATING SERUM LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR-A WITH VASCULAR ULTRASOUND DETERMINANTS OF DEMENTIA IN PATIENTS WITH TYPE.

Toujeo® and it’s Place in Therapy

ASSOCIATION OF HYPOVITAMINAEMIA D AND TRANSFORMING GROWTH FACTOR – β1 IN THE PROGRESSION OF CHRONIC KIDNEY DISEASE Grigorios G. Dimas 1, Ilias E. Kanellos.

Effect of Hypertension and Dyslipidemia on glycemic control among Type 2 Diabetes patients in Thailand Dr. Mya Thandar DrPH Batch 5 1.

MENU ΣΤΕΦΑΝΙΑΙΑ ΝΟΣΟΣ ΣΕ ΔΙΑΒΗΤΙΚΟΥΣ ΚΑΙ ΗΛΙΚΙΩΜΕΝΟΥΣ.

INCREASED CIRCULATING SERUM LEVELS OF TGFβ-1 AND IL-6 ARE ASSOCIATED WITH THE PROGRESSION OF CΗRONIC KIDNEY DISEASE IN ATHEROSCLEROTIC PATIENTS WITH TYPE.

 Parkinson’s Disease (PD) -progressive neurodegenerative disease affecting motor ability -third most common neurologic disorder of older adults.

Hypertension Family Medicine Specialist CME October 15-17, 2012 Pakse.

The evolution of non-motor symptoms in patients with Parkinson’s disease treated with Duodopa intestinal gel Natalia Pritcan Doctor Jozsef Attila Szasz.

Improvement of life quality and non motor symptoms relief in patients with advanced Parkinson's disease. Natalia Prican Andra Oltean Doctor Jozsef Attila.

SERUM LEVELS OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 AND OX-LDL ARE ASSOCIATED WITH ATHEROSCLEROSIS IN PATIENTS WITH CΗRONIC KIDNEY DISEASE Grigorios.

ANTIPLATELET TREATMENT IN PATIENTS WHO HAVE AN ISCHEMIC STROKE WHILE TAKING ASPIRIN Konstantinos Tziomalos, Stella D. Bouziana, Marianna Spanou, Stavroula.

FIBROBLAST GROWTH FACTOR-23 AND HYPOVITAMINAEMIA D IN ANAEMIA OF TYPE 2 DIABETIC NEPHROPATHY Grigorios G. Dimas 1, Fotios S. Iliadis 1, Ilias E. Kanellos.

second most common neurodegenerative disorder progressive loss of muscle control trembling of the limbs and head while at rest stiffness, slowness, and.

Heart failure and comorbidities

A Multifaceted Continuing Medical Education Intervention to Improve Primary Care Physicians’ Performance In Mexico Hortensia Reyes, Ricardo Perez-Cuevas,

By Katelyn Chaimson and Sean Guyot

Α-synuclein transgenic mouse models of Parkinson’s disease Michelle Maurer December 2015.

INCREASED CIRCULATING SERUM LEVELS OF TGFβ-1 AND MMP-2 ARE ASSOCIATED WITH INFLAMMATION AND PROGRESSION OF CΗRONIC KIDNEY DISEASE IN PATIENTS WITH TYPE.

 Parkinson Disease (PD) is a progressive disorder of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions.

Expression profile of oncomiRs and tumor-suppressor miRs in urothelial carcinoma of the bladder Apostolos Zaravinos 1, George I. Lambrou 2, Jelena Radojicic.

Mexican Institute of Social Security A Multifaceted Continuing Medical Education Intervention to Improve Primary Care Physicians’ Performance In Mexico.

INCREASED CIRCULATING SERUM LEVELS OF VEGF-A ARE ASSOCIATED WITH ALBUMINURIA IN HYPETENSIVE PATIENTS Grigorios G. Dimas 1, Thomas J. Tegos 2, Ilias E.

Dr. Nadira Mehriban. INTRODUCTION Diabetic retinopathy (DR) is one of the major micro vascular complications of diabetes and most significant cause of.

The CHART-2 Study (The Chronic Heart Failure Analysis and Registry in the Tohoku District 2) Source Shiba N, Nochioka K, Miura M, et al. Trend of westernization.

Circulation. 2014;129: Association Between Plasma Triglycerides and High-Density Lipoprotein Cholesterol and Microvascular Kidney Disease and Retinopathy.

The short term effects of metabolic syndrome and its components on all-cause-cause mortality-the Taipei Elderly Health Examination Cohort Wen-Liang Liu.

Potential of D-cycloserine in the treatment of behavioral and neuroinflammatory disorders in Parkinson's disease and studies that need to be performed.

Multicentric study on the management of Acute Hypertensive Events

Parity and incidence of diabetes Mellitus

Neurocognitive test battery

Association between Systolic Blood Pressure

Parkinson’s Disease Celsey and Chylee.

Risk of post-operative stroke in patients with known extra-cranial carotid artery disease undergoing Non-Cardiac Surgery Heart and Vascular.

Mean Platelet Volume (MPV), Neutrophil-to Lymphocyte Ratio (NLR) & Platelets-to-Lymphocyte Ratio (PLR) In association With Cardiovascular Disease In.

Dopamine AND PD.

New Insights Into Neurogenic Orthostatic Hypotension

A Multifaceted Continuing Medical Education Intervention to Improve Primary Care Physicians’ Performance In Mexico Hortensia Reyes, Ricardo Perez-Cuevas,

Figure 2 Striatal dopamine transporter binding with the SNCA A53E mutation Transaxial planes of [123I]FP-CIT SPECT on the striatal level are presented.

MHE diagnosis – Stroop test

Presentation transcript:

DIABETES MELITUS, HYPERTENSION AND PARKINSON DISEASE IN A COMMON THREE LEAF CLOVER NEURODEGENERATIVE PATHWAY Grigorios G. Dimas 1, Charikleia T. Sachinidou 1, Zanina G. Rantev 1, Ilias E. Kanellos 1, Georgios Balanikas 2, Thomas J. Tegos 3, Spiros D. Fotiadis 1, Alexandra N. Tranta 1, Ioannis M. Karamouzis 1, Alexandros Alexandridis 2, Christos G Savopoulos 1, Apostolos I Hatzitolios st Propaedeutic Medical Department, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece 2 1 ST OPTHALMOLOGY DEPARTMENT, AHEPA UNIVERSITY HOSPITAL, ARISTOTLE UNIVERSITY OF THESSALONIKI, GREECE 3 1ST NEUROLOGY MEDICAL DEPARTMENT, AHEPA UNIVERSITY HOSPITAL, ARISTOTLE UNIVERSITY OF THESSALONIKI, GREECE

Background Diabetes mellitus (DM) is the most common metabolic disease worldwide. The largest percentage of those patients, especially over 65 years suffer from hypertension (HT). Insulin and dopamine act interdependently, especially in the elderly, concerning Parkinson disease (PD). In animal models, hypo-insulinemia induced by streptozocin decreases the levels of dopamine transporter and hydroxylase of tyrosine in the pars compacta of the substantia nigra. Several factors have been implicated concerning the coexistence of these diseases.

Aim The aim of the present study was to correlate those three diseases in patients who were examined in our patient clinic during the last two years.

Methods 445 patients with DM type 2 were included. 180 of them were over 75 years old. The percentage of HT and PD was investigated in those patients.

Results The results show that 303 (68%) patients of the whole suffered from HT and 71 (15.9%) patients from PD. The results were more pronounced in the patient group over 75years old and in 180 octogenarians diabetic patients, 142 (78.88%) suffered from HT and 48 (26.66%) suffered from PD.

Conclusion This study suggests a clear impact on aging diabetic population of HT and PD.