DNA Replication – Exciting stuff from chapter 10!

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Presentation transcript:

DNA Replication – Exciting stuff from chapter 10!

Ch 10 DNA Replication, Baby! DNA workshop – interactive basic overview: Link to replication animation w/ no sound: Link to genetically engineered corn video: Link to narrated DNA replication hill.com/sites/ /student_view0/chapter14/animations.html# hill.com/sites/ /student_view0/chapter14/animations.html# Link to DNA replication mhttp:// m

Review Structure The "rungs" are the nitrogenous base pairs a. complementary base pairing Uniform diameter

Review DNA function Stores information Mutates

Replicates Expressed

DNA REPLICATION When and where? How about in bacteria?

Bacteria replication of DNA: one origin of replication

DNA replication in eukaryotes: Contain hundreds of origins and complexes make replication “________” that eventually fuse

not Replication is called______ _________, because one half of the original strand is always saved, or "conserved"

Process of DNA replication: 1. enz. helicase unwinds and breaks H-bonds 2. single-stranded binding proteins stabilize the molecule

3. enz. _________ adds a small piece of _____ (called a primer) to origin of replication (DNA nucleotides can only be added to the end of an _________ chain)

4. enz. DNA ____________adds new dNTPs to the ____ end - A-T, G-C, 5'  3 direction of growing strand

leading strand - one primer needed lagging strand - Okazaki fragments - primer needed for each fragment

5. A dif. DNA polymerase replaces RNA ___________ w/ DNA 6. enz. DNA ________ joins Okasaki fragments together

Ch 10 DNA Replication, Baby! DNA workshop – interactive basic overview: Link to replication animation w/ no sound: Link to genetically engineered corn video: Link to narrated DNA replication hill.com/sites/ /student_view0/chapter14/animations.html# hill.com/sites/ /student_view0/chapter14/animations.html# Link to DNA replication mhttp:// m

Telomeres - repetitive sequences of nucleotides at the ends of DNA shorten w/ each rep. purpose?

Enz. ______________extends telomeres in certain cells 1. stem cells 2. cancer cells

Excision repair - repair of damage due to chemicals, radiation, X-rays, UV light What is the result of uncorrected errors? Can mistakes that occur to DNA be repaired?