PAKI CHECK NAMAN KUNG TAMA MGA NILAGAY KO TNX DI PA KUMPLETO YAN

Macrolide - MOA: blocks transpeptidation by binding to 50s ribosomal subunit of susceptible organisms and disrupting RNA-dependent protein synthesis at the chain elongation step. –Community-acquired pneumonia can be treated –Dose: Azithromycin –loading dose : 500 mg PO once, then 250 mg single daily dose –Adverse effects: Mild to moderate nausea, vomiting, abdominal pain, dyspepsia, flatulence, diarrhoea, cramping; angioedema, cholestatic jaundice; dizziness, headache, vertigo, somnolence; transient elevations of liver enzyme values.

NAKUHA KO YAN SA KATZUNG CHECK NYO DIN HARRISON’S PAGE 1623 COST AND EFFICACY DI KO ALAM

Diuretics lower blood pressure by depleting the body of sodium and reducing blood Thiazide –MOA: inhibits sodium chloride transport in the early segment of DCT – appropriate for most patients with mild or moderate hypertension and normal renal and cardiac function –Dose: mg daily Adverse effect: –Hypokalemic metabolic alkalosis

Katzung at MIMS ko nakuha

Calcium Channel Blocker MOA: –relaxes peripheral and coronary vascular smooth muscle –produces coronary vasodilation by inhibiting the entry of Ca ions into the voltage-sensitive channels of the vascular smooth muscle and myocardium during depolarisation. –increases myocardial O2 delivery in patients with vasospastic angina. Dose: Adverse Effects:

Non - Pharmacologic Patient’s education –KASAMA NA JAN UNG SA DM (kasi di pa naman naddiagnose na may DM d b?) and PTB (di pa rin sigurado)