The Discovery of HHV-8 Kaposis sarcoma was one of the original clinical syndromes that led to the discovery of HIV Thought for many years that the cause.

Slides:

Advertisements

Similar presentations

HIV TB. World wide TB is the most common cause of death in people with HIV About 1/3 of HIV infected people worldwide are co-infected with TB (co-infection.

Advertisements

The Epidemiology of HIV/AIDS in the Republic of Trinidad/Tobago With special reference to Women and Children Robert K. Lee MB,ChB;MPH.

History of HIV First appeared in USA in early 1980’s

2004 ISHLT J Heart Lung Transplant 2004; 23: HEART TRANSPLANTATION Pediatric Recipients.

HEART TRANSPLANTATION Pediatric Recipients ISHLT 2007 J Heart Lung Transplant 2007;26:

HEART-LUNG TRANSPLANTATION

SPAIIN Where are we now?. Key concepts in clinical networks Equitable Efficient High quality Locally delivered Patient/Carer involvement ‘designed to.

Methods for establishing the extent of HIV epidemics and trends in prevalence Geoff Garnett Imperial College London.

Trends in Herpes Simples Virus Type 2 infection in the United States Fujie Xu, Geraldine McQuillan, Benny Kottiri, Maya Sternberg, Francis Lee, André Nahmias,

Diagnosis and Management of Acute HIV Infection HIV Clinical Guidelines from the New York State Department of Health AIDS Institute January 2010 HIV CLINICAL.

Is Nucleic Acid Testing for Organ Donors the ‘Right’ Choice? Reference: Humara A, Morrisb M, Blumbergc R, et al. Nucleic acid testing (NAT) of organ donors:

Human Herpesvirus 8 (HHV-8) as an Emerging Pathogen: Relevance to Semen Donation Michael J. Cannon, Ph.D. Centers for Disease Control and Prevention.

The HIV/AIDS Epidemic © 2005 John B. Pryor Illinois State University.

Immune deficiency Diseases (2). Immune Deficiency Disorders Immunodeficiencies can be divided into primary immunodeficiency disorders, and secondary immunodeficiency.

Curable versus incurable STDs. Objectives To describe the natural history and epidemiology of two curable STDs (i.e. syphilis and chlamydia) and two non-

HIV Prevention Understanding the HIV virus is very important. Each of us needs information, not only for ourselves, but to be able to discuss it with others.

 AIDS- Acquired Immune Deficiency Syndrome, is a serious viral disease that destroys the body’s immune system  HIV-The virus (Human Immunodeficiency.

The HIV/AIDS Epidemic © 2013 John B. Pryor Illinois State University.

Varicella Zoster Virus Herpesvirus (DNA) Primary infection results in varicella (chickenpox) Recurrent infection results in herpes zoster (shingles) Short.

HIV Basics. What is HIV? Human Immunodeficiency Virus ◦ Two Strains  HIV-1  HIV-2 Kills special blood cells that help fight off infections ◦ CD4+ Virus.

EPIDEMIOLOGY Epidemiology of chronic kidney injury, including prevalence and prognosis in various community groups. Screening of populations for kidney.

INDIA and HIV/AIDS Student Example 2009 Comprehensive Health Education.

The Silent Epidemic Any pathogen that spreads from one person to another during sexual contact is called a sexually transmitted infection, or STI. More.

 HIV stands for › HUMAN IMMUNO-DEFICIENCY VIRUS › It is the virus that primarily infects cells of the immune system and that causes the disease known.

Section 22.3 HIV and AIDS Objectives

Microbiology B.E Pruitt & Jane J. Stein AN INTRODUCTION EIGHTH EDITION TORTORA FUNKE CASE Chapter 19, part B Disorders Associated with the Immune System.

HIV is the virus that causes AIDS, a disease that weakens the body’s immune system and may have fatal consequences.

Senior Health Mr. Weigel

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint ® Lecture Slide Presentation prepared by Christine L. Case M I C R.

HIV/ AIDS Right now, 1 out of every 300 people in the United States has HIV, the virus that causes AIDS.

Bi 10e.  AIDS is the sixth leading cause of death among people ages in the United States, down from number one in  The World Health.

AIDS in Sub Saharan Africa AIDS – a virus with no known cure first identified in the Belgian Congo in It’s now a global epidemic, and poverty and.

Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents Human Herpesvirus-8 Slide Set Prepared by the.

Epstein-Barr Virus Brittany Seyler.

Human Immunodeficiency Virus (HIV) This virus causes HIV infection and AIDS The HIV infected person may, or may not have AIDS. They may, or may not, have.

Non-Hodgkins Lymphoma. risk factor Elderly Men Predisposed: primary and secondary immunodeficiency states – HIV infection – Undergone organ transplantation.

HIV-1 & HIV : Robert Gallo: HTLV-1/ lymphocytes 1978: Robert Gallo: HTLV-1/ lymphocytes of leukemia patients of leukemia patients HTLV :

Human Immunodeficiency Virus VIRUSES.

Chapter 25 Lesson HIV & AIDs.

School: Shrimati Indira Gandhi SSS, Mauritius Age group: Form 4, yrs Subject: Art and Design.

HEALTH I Section 3-4 Mr. Martin

 HIV stands for › HUMAN IMMUNO-DEFICIENCY VIRUS › It is the virus that primarily infects cells of the immune system and that causes the disease known.

THE HIV/AIDS EPIDEMIC A quick look at the global killer Carla Mollica June 2013 – MGD 120.

Epidemiology of Transfusion Transmitted Disease Sharyn Orton, MT(ASCP)SBB, M.S.P.H, Ph.D. candidate Project Leader, Transmissible Diseases Department American.

Dan Dougherty and Allie Capetola Period 5.  Human immunodeficiency virus  Leads to AIDS (Acquired immunodeficiency syndrome)  HIV is spread through.

HIV AND AIDS IN SUB-SAHARAN AFRICA By: Matt, Tim, and Alana.

29-1 A Human Perspective HIV Disease and Complications of Immunodeficiency Eugene Nester Denise Anderson Evans Roberts, Jr. Nancy Pearsall Martha Nester.

Interventions for Clients with HIV/AIDS and Other Immunodeficiencies.

Hepatitis B Neha Patel, Rebecca Webber, Lilimae Martin.

Prepared by the AETC National Coordinating Resource Center based on recommendations from the CDC, National Institutes of Health, and HIV Medicine Association/Infectious.

Provider Initiated HIV Counseling and Testing Unit 1: Introduction to HIV/AIDS.

The human immunodeficiency virus The human immunodeficiency virus (HIV) is a retrovirus responsible for the acquired immune deficiency syndrome (AIDS).

Lesson 1 & 3. Objectives  Identify high risk behaviors that put teens at a great risk for STD infection  Understand how HIV effects the body and its.

HIV / AIDS Health Education. HIV / AIDS Terms and Info HIV – Human immunodeficiency virus A virus that causes AIDS (acquired immunodeficiency syndrome)

HIV/AIDS Health Mr. Christman. Objectives 1) Describe how HIV affects and destroys the immune system. 2) Identify behaviors known to transmit HIV. 3)

Chapter 25 Lesson 3 HIV & AIDs.

Initiative taken by Health Camp

Viruses That Can Cause Cancer

HIV Infection in Women in Our Community: The Continuum of Care

AIDS: Research By Ghinna Fondinka.

HIV TESTING IN NEWLY DIAGNOSED LYMPHOMAS IN NOTTINGHAM CITY HOSPITAL

Immunodeficiency (2 of 2)

HIV and dental care in NZ HIV Women’s Seminar Auckland 22 June 2018

PHARMACOTHERAPY III PHCY 510

Immunodeficiency (2 of 2)

Presentation transcript:

The Discovery of HHV-8 Kaposis sarcoma was one of the original clinical syndromes that led to the discovery of HIV Thought for many years that the cause was infectious The virus was discovered in 1994 by Yuan Chang and colleagues at Columbia University Belongs to a family of viruses which cause cancer known as the gammaherpesvirus family

How is HHV-8 Transmitted ? Sexual Transmission HHV-8 infection has been linked to a history of various Sexually Transmitted Diseases No specific sexual behavior that results in infection has been identified Mother to Child In Africa, infections are rare before age two, but the number of infections in puberty is identical to adult prevalence. This suggests that children may get HHV-8 from their family Transmission through Blood Transmission through Saliva

High seroprevalence of antibodies to HHV-8 in Egyptian children: evidence of non-sexual transmission EBVCMV HHV-6 Years HHV-8 Years Andreoni. J nat cancer Inst. 1999

The clinical disease that is classically associated with HHV-8 infection is KS and less commonly Castlemans disease and primary effusion lymphoma (PEL). These HHV-8-associated diseases occur most commonly among immunocompromised patients, such as HIV-infected patients, those with end- stage renal disease, and transplant recipients. In the United States, the incidence of transplant associated KS is 10 to 20 times higher than the general population

The natural history of human herpesvirus 8 infection: clinical stages and determinants of progression.

Progression to KS stratified by HHV8 antibody titers Risk of Kaposis Sarcoma Adjusted RH 51.8 Adjusted RH 24.8 Rezza G, Journal of National Cancer Institute, 1999

Manifestazioni cliniche dellinfezione primaria di HHV8 nellimmunocompromesso Febbre, artralgia, linfoadenopatia (iperplasia angiolinfoide), splenomegalia e citopenia. HIV+ (Oksehendler NEJM 1998) Febbre, splenomegalia, pancitopenia. 2 trapiantati rene HHV-8 negativi. (Luppi NEJM 2000) Multiorgan failure. Bambina di un mese con S. Di George (Sanchez-Velasco, JID 2001) Febbre, sudorazioni, linfoadenopatia, epatite (Marcelin AIDS, 2000) Diarrea, linfoadenopatia rash. 5 omosessuali HIV negativi (Wang, Blood 2001) Esantema maculopapulare e artrite. Donna con artrite reumatoide (Herpesvirus infections, Parigi 2001)