1 Carboxylic Acids Esters, Amines Amines Reactions of Amines

2 Amines Organic compounds of nitrogen N Classified as primary, secondary, tertiary CH 3 CH 3  CH 3 —NH 2 CH 3 —NH CH 3 —N — CH 3 1° 2° 3°

3 Naming Amines IUPAC aminoalkane Common alkylamine CH 3 CH 2 NH 2 CH 3 —NH —CH 3 aminoethane N-methylaminomethane (ethylamine) (dimethylamine) NH 2 | CH 3 CHCH 3 2-aminopropane AnilineN-methylaniline (isopropylamine)

4 Learning Check AM1 Give the common name and classify: A. CH 3 NHCH 2 CH 3 CH 3 | B.CH 3 CH 2 NCH 3

5 Solution AM1 A.CH 3 NHCH 2 CH 3 ethylmethylamine, 2° CH 3 | B.CH 3 CH 2 NCH 3 ethyldimethylamine, 3°

6 Reactions of Amines Act as weak bases in water CH 3 NH 2 + H 2 O CH 3 NH OH – methylammonium hydroxide Neutralization with acid gives ammonium salt CH 3 NH 2 + HClCH 3 NH 3 + Cl – methylammonium chloride

7 Alkaloids Physiologically active nitrogen-containing compounds Obtained from plants Used as anesthetics, antidepressants, and stimulants Many are addictive

8 Nicotine

9 Caffeine

10 Procaine

11 Leaning Check AM2 Write a structural formula for A. 2-aminopentane B. 1,3-diaminocyclohexane