Additional File 4. Relationships between numbers of probes remaining after masking and rates of evolution. For each tissue and species, the number of 1H_1C.

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Additional File 4. Relationships between numbers of probes remaining after masking and rates of evolution. For each tissue and species, the number of 1H_1C probes in a probe set is plotted against the fraction of corresponding RefSeq sequences with nonsynonymous / synonymous rate ratios (dN/dS) either: (i) less than 0.25 (black), (ii) between 0.25 and 0.5 (green), (iii) between 0.5 and 1.0 (blue), or (iv) greater than 1 (orange). Note that only probe sets expressed in a given tissue are considered in this analysis (see Methods for details).

Brain dN/dS Human Number of 1H_1C Probes fraction of probe sets by dN/dS Brain dN/dS Chimp Kidney dN/dS Human Kidney dN/dS Chimp Number of 1H_1C Probes < > 1 < > 1 < > 1 < > 1 fraction of probe sets by dN/dS

Liver dN/dS Human Liver dN/dS Chimp Heart dN/dS Human Heart dN/dS Chimp Number of 1H_1C Probes < > 1 < > 1 < > 1 < > 1 fraction of probe sets by dN/dS

Testis dN/dS Human Number of Probe Sets Testis dN/dS Chimp Number of Probe Sets < > 1 < > 1 fraction of probe sets by dN/dS