Size and apolipoprotein composition are the main factors determining atherogenicity of triglyceride-rich particles.

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Presentation transcript:

Size and apolipoprotein composition are the main factors determining atherogenicity of triglyceride-rich particles

Apo C-III modulates VLDL

Apo C-III in apo B particles is atherogenic

Relationship between apo C-III in apo B containing lipoproteins and atherogenicity

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HDL: apo AI-rich particles

Apo A-I protects against atherosclerosis

Apo A-II protects against atherosclerosis The human apo A-II transgenic mouse model