Functional Antigenics UBI / UBI Asia Molecular Design of Functional Antigens Adjuvant & Formulation Technologies UBITh ® Technology Synthetic Peptide Technologies.

Slides:



Advertisements
Similar presentations
Topics 6&11 Defence against infectious disease cont’d.
Advertisements

Chapter15 B cell mediated immune response. B cells mediated immune response Humoral immunity(HI) or antibody mediated immunity: The total immunological.
Acquired Immune Response Sanjaya Adikari Department of Anatomy.
HOW VACCINE PROVIDES PROTECTION STIMULATORY MOLECULE SECRETIONS B CELL MACROPHAGE Step1 Macrophage takes in antigen by phagocytosis Step2 Macrophages display.
Lecture 4 Activation of Adaptive Immunity. Overview In order to initiate an immune response antigen must be recognized. In order to initiate an immune.
Immunotherapy K J. Goodrum Immunotherapies Vaccines (toxoid, attenuated live, killed cell vaccines, subcellular, DNA, peptide) Adjuvants (nonspecific.
Manipulation of the Immune Response Chapter 14
Principles of Immunology Overview of Adaptive Immunity 1/24/06 “Too many people overvalue what they are not and undervalue what they are.” M Forbes.
Specific Immunity.
General Microbiology (Micr300)
Principles of Immunology Antigens 2/9/06 “It is only when you give of yourself that you truly give.” K Gibran.
Immunity : The Immune system plays a role in combating infection, creating inflammation (& consequently heart disease), controlling (or not) cancer and.
Design of immune system Immune system Self/non-self recognition The state of protection from infectious disease 自我非我 Memory Acceptance vs rejection 疫苗.
Lecture 16 Cellular Cooperation and Antigen Recognition.
 Cell surface molecules expressed (or disappeared) during different developmental and differential phases, activation or inactivation process of blood.
Reasons to Choose Taiwan UBI Asia in Partnership with UBI
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Chapter 14 Specific Immunity (adaptive immunity)
Cancer Immunotherapy Manipulation of co-stimulatory signals Enhancement of APC activity Cytokine therapy Monoclonal antibody therapy.
General classes of vaccines An induced mobilization of the immune response for the purpose of therapeutic benefit. Preventative: infectious agents Therapeutic:
The Immune System memory and specificity Chapter 43
Immunogenetics chapter 22 select topics pp
The study on the effect of foot- and-mouth disease virus titer to the result of detected neutralization antibody titer Hog Cholera Research Division Lin.
Detecting and Responding to Invaders. The Immune System Specific Response Non-Specific.
Adaptive/Acquired Immunity
Health and the Immune System This presentation is available online.
T-LYMPHOCYTE 1 Lecture 8 Dr. Zahoor. Objectives T-cell Function – Cells mediated immunity Type of T-cells 1. Cytotoxic T-cell – CD8 (Killer T-cell) 2.
12 Immune Response to Biomaterials CHAPTER
Highlights of Immune System. Topic Outline Overview of the Immune System 1 st and 2 nd lines of Defense The Immune System  B cells  The antibody & antibody.

Medical ImmunologyDEPARTMENT OF IMMUNOLOGY 1  Immune system itself  Neuro-endocrine system Components of Immune Regulation.
制作人 张晓东 张晗晖 韩思奇 尹利国 梁婷婷 张莹 徐芳 Source Mechanism Function Diseases ( IDDM ) Therapy prospect catalogue.
1 How we prevent infection. 2 Ch Innate Immunity.
Adaptive Immunity David, “Bubble Boy” 1980 from 2011 CBS News 40-year retrospective 2011.
Tom Whitelaw Max McGill Innate Immunity Invertebrates- They have physical and chemical barriers to guard against microbes, as well as cell based.
14. Immunodiagnosis, Immunotherapy & Vaccination 王 家 鑫, MD College of Veterinary Medicine.
Lecture 6 clinical immunology Cytokines
Antigen presentation to T cells Zheng W. Chen, M.D., Ph.D.
T -lymphocytes T cell receptor T – cytotoxic (CD8) cells
T Cells Lacey Jeong. What is a T Cell?? Thymus cell – produced and processed by the thymus gland Lymphocyte (white blood cell) – protect body from infection.
Immunogenetics chapter 21 pp. pp Lines of Defense Physical and Chemical Physical and Chemical Immune system Immune system 3 rd line 1 st and.
Tolerance and Autoimmunity
3/17/08 Lymphatic System Chapter 20 – Day 3. 3/17/08 Immune Response  Definition of Immunity  Lines of defense – non-specific vs. specific  Characteristics.
ایمونولوژی سرطان پزشکی -آذرماه 1387.
Lecture 16 Cellular Cooperation and Antigen Recognition
Immune Responses to HIV
Immune System Basics Immunity: The capacity to resist infectious pathogens. Pathogens: Disease-causing organisms Self vs. Non-self recognition Major Histocompatibility.
Summary J.Ochotná.
Hepatic AAV Gene Transfer and the Immune System: Friends or Foes?
Topic 11.1: Antibody Production and Vaccination
Major Histocompatibility complex OR
Figure 1 CTLA-4 and PD-1–PD-L1 immune checkpoints
Chapter 15: The Adaptive Immune Response
Tumor Immunology Ali Al Khader, MD Faculty of Medicine
Immune System Project : CD28
Humoral & Cell-mediated immunity
Differentiation and Functions of CD8+ Effector T Cells
Figure 4 Combination immunotherapeutic approaches with imatinib
Rare cells predict GVHD
Nat. Rev. Urol. doi: /nrurol
Transplantation.
T –HELPER CELL AMMAR HADI
Mechanism of CTLA-4-induced immunosuppression.
Nat. Rev. Endocrinol. doi: /nrendo
Humoral and Cell Mediated Immunity
Immunogenetics chapter 22 select topics pp
SCIENCE HIGH SCHOOL CP BIOLOGY
B cell T cell.
Tumor Immunology Ali Al Khader, MD Faculty of Medicine
BATF3-expressing professional antigen-presenting cells (DC) are able to cross-present tumor antigen (TA) by channeling material taken up from their environment.
Stable IL-10: A New Therapeutic that Promotes Tumor Immunity
Presentation transcript:

Functional Antigenics UBI / UBI Asia Molecular Design of Functional Antigens Adjuvant & Formulation Technologies UBITh ® Technology Synthetic Peptide Technologies Antigenic Combinatorial Library Cytotoxic T Lymphocyte Neutralization Antibodies Vaccine: Preventive Therapeutic Serology Diagnostics Therapeutic Monoclonal Antibody Deimmunization

Pathways to Vaccines & Immuno-therapeutics Animal Health Products Human Health Products Functional Antigenics Canine Allergy Therapeutic FMDV Vaccine LHRH Vaccine for Boar Taint Removal & Growth Promotion LHRH Vaccine as Pet Contraceptive SARS Vaccine LHRH Vaccine as Prostate Cancer Therapeutic HIV/AIDS Vaccine & Therapeutic Allergy Therapeutic Alzheimer Disease Therapeutic

功能抗原設計學的作用機制 ( 以 UBI ® 口蹄疫疫苗為例) 口蹄疫病毒 Pentamer Protomer VP1 VP2 VP3 VP1 蛋白 UBITh ® 口蹄疫 VP1 胜肽 Vaccine formulation B Cell Processing Th1 MHC II/ peptide TCR CD40 CD154 CD80 CD28 IL-4 IL-5 IL-6 APC Processing CD80 CD28 IL-1  IL-1RI MHC II/ peptide Th2 IL-2 Y Y INF-  (anti-viral) 口蹄疫 Vaccination Memory B cell Plasma cell 抗口蹄疫抗體