NA-MIC National Alliance for Medical Image Computing Geodesic Tractography Segmentation DTI Tractography Workshop, Oct. 1-2, Santa Fe, NM John Melonakos Georgia Institute of Technology
Algorithm Update Here describe any new development made since the July 31 st tcon: –“Look Ma’ No Hands” matlab code –Successfully applied to the cingulum bundle, fornix, uncinate fasciculus –Still working on the arcuate fasciculus –Not ideal for internal capsule
Input parameters Data: –Resolution: Downsampled –Raw +/- Eddy Current: EdCor Pre-processing steps: –Masking: for speed and accuracy Algorithm parameters: –Mean Fiber Radius
User interaction
Specifications Computational Resources: (e.g: Processor, Memory, Platform) –Dell Inspiron Laptop –2GB Memory –Linux OS Average algorithm execution time per case: –8 minutes for initial case –6 minutes for subsequent cases
Results Measurements calculated on the data: –Tensor statistics along the tract Can be given as a function of arc length Visual tractography output: –Fiber bundle segmentation Advantages and difficulties of the method: –Adv: Yields both optimal connectivity information and explicit structural segmentations –Dif: Struggles with fanning fiber structures
Comments on Seed Regions CBFX
Comments on Seed Regions UFAF
Results
Color by Orientation Fractional Anistotropy
Results Left CB
Results Right CB
Results Left UF
Results Right FX
Results Left UF
Results Right UF
Future Work Adapt to Arcuate Fasciculus –and other fanning fibers structures Statistics GPU Implementation for Speed Apply to more fiber types, more cases – have more fun!
Questions?