TM Group Research Applications   Tumor Growth Modeling   Laser Treatment of Cancer   Modeling Angiogenesis Algorithms & Modeling   Phase-Field Models   Stochastic PDEs   Model Selection - Bayesian Methods   Verification, Validation, and UQ   Complex Vasculature & Tissue Properties   Dynamic Data Driven Application Systems Funding: NIH, NSF, AFOSR Modeling the Process of Angiogenesis Tom Yankeelov Lead Affiliated Faculty Nichole Rylander Tinsley Oden Research Staff: Ernesto Lima, Aimr Shahmoradi

2 DDDAS – Prostate Cancer DDDAS – Prostate Cancer - Cyberinfrastructure and Work Flow - TMG  Data Acquisition  Geometry Extraction  Mesh Generation  Laser  Parameter Optimization Optimization  Registration  Data Transfer  Patient Specific Calibration Calibration  Model Validation  Data Filtering  Predictions  Visualizations

3 DDDAS – Prostate Cancer DDDAS – Prostate Cancer - Imaging to Mesh Generation Pipeline - TMG

4 DDDAS – Prostate Cancer DDDAS – Prostate Cancer - Patient Specific Calibration - TMG

DDDAS – Prostate Cancer DDDAS – Prostate Cancer - Treatment Process - TMG 5