Hematopoietic Cancers Common Disruptions 1. 2 3.

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Presentation transcript:

Hematopoietic Cancers Common Disruptions 1

2

3

Burkitt’s Lymphoma 4

5

6 Endemic Lymphoma (comorbid with Malaria & EBV infection)

Epstein-Barr Virus (EBV)? Avian Myelocytomatosis Virus 7

8

9

10

11

N--C 12

bHLH E-box: CACGTG 13

14

15

16

17

18

19

cyclin D + CDK4 20

21

22

23

24

25

ALL 26

Delta/Jagged Growth promoting gene transcription 27

Growth promoting gene transcription Extracellular 28

CML 29

30

31

32

33

34

35

36

37

38

39

40

41

42

43

44

45

46

Hodgkin’s Lymphoma 47

48

49

AML 50

c-Kit 51

52

FLT3 53