Psychology Drug Abuse

Psychology 3552 General Overview Problem of drug abuse Review of synaptic transmission Brain reward systems Mechanisms of tolerance and dependence

Psychology 3553 Drug abuse

Psychology 3554 Drug abuse Opioids and Morphine Derivatives Codeine Fentanyl Heroin Morphine Opium Stimulants Amphetamine Cocaine Ecstacy (MDMA) Methamphetamine Methylphenidate (Ritalin) Nicotine Other Compounds Anabolic Steriods Inhalants Cannabinoids Hashish Marijuana Depressants Barbiturates Benodiazepines Flunitrazepam (Rohypnol) Methaqualone (Quaaludes) Dissociative Anesthetics Ketamine PCP Hallucinogens LSD Mescaline Psilocybin

Psychology 3555 Drug abuse

Psychology 3556 Chemical synapses Basic Steps Neurotransmitter synthesis Load neurotransmitter into synaptic vesicles Vesicles fuse to presynaptic terminal Neurotransmitter spills into synaptic cleft Binds to postsynaptic receptors Biochemical/Electrical response elicited in postsynaptic cell Removal of neurotransmitter from synaptic cleft

Psychology 3557 Chemical synapses Neurotransmitters Amino acids: Small organic molecules e.g., Glutamate, Glycine, GABA Amines: Small organic molecules e.g., Dopamine, Acetylcholine, Histamine Peptides: Short amino acid chains (i.e. proteins) stored in and released from secretory granules e.g., Dynorphin, Enkephalins

Psychology 3558 Chemical synapses

Psychology 3559 Chemical synapses Receptors, agonists, & antagonists

Psychology Chemical synapses

Psychology Reinforcement

Psychology Reinforcement

Psychology Reinforcement

Psychology Reinforcement

Psychology Reinforcement

Psychology Tolerance and dependence

Psychology Tolerance and dependence

Psychology Tolerance and dependence

Psychology Tolerance and dependence

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Psychology 35530