Page No. 1 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Sponsoring Org/Office Code: OZ Date: January 2012 INCREMENT 33/34 PAYLOAD PROGRAM STATUS Anita WeaverMatt Metzinger Increment Payload ManagerIncrement Payload Engineer Steve HuningCindy Romero Lead Increment ScientistLIS Representative Pat PattersonDonna Simpson Payload Operations Manager/Lead PODAssistant POM/Asst Lead POD POIWG #31

Page No. 2 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Presentation Overview Program changes Upmass Summary Downmass Summary Crew time Summary Cold Stowage Summary Research Objectives and Highlights Investigation List Experiment Locations Increment Concerns

Page No. 3 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Program Changes Current Flight Program sequence reflects no changes in Orbital or SpaceX flights (including the demo flights) Program discussions in work for launch date changes –Orb-D1 has pad readiness issues. Projected to be ready in August 2012 timeframe. SpX-1 is currently in early August –SpX-D flight schedule is being discussed in Program Quarterly meetings this week. Likely to move past ATV-3 launch. ATV-4 launch date discussion is still in work

Page No. 4 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Upmass Summary There is still no allocation for Progress flights during this Increment In April the Program will ask for allocation on 50P. (total of 180 kg for all ISS orgs) 50P will likely slide to Feb There isn’t margin to cover additional allocation on 32S. Will have to look at priorities for when science/resupply is needed on- board FlightCurrent Allocation (kg) Internal PTP req (kg) External PTP req (kg) Total PTP req (kg) Unfilled Allocation (kg) 32S Orb P S SpX * 50P00000 ATV * Note: Open changes impact current unfilled allocation

Page No. 5 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Downmass Summary Cold stowage plan is to return 2 full Glaciers and 5 double coldbags FlightCurrent Allocation (kg) Internal PTP req (kg) External PTP req (kg) Total PTP req (kg) Unfilled Allocation (kg) 31S82026 SpX * 32S * Note: Open changes impact current unfilled allocation

Page No. 6 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Crew Time Summary We currently have 910 hours of primary utilization accounted for in the IDRD (35 hours/week) –Prior to the preliminary OOS and the final OOS, we will look at all the crew time on the books and rebalance crew time per the priorities IP Crew Time Allocation Nominal PTP requirements Reserve PTP requirements IDRD910 Commissioning1.83 NASA JAXA ESA CSA Total Requirements

Page No. 7 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Pending PTP Changes CEFTitle CEF Status UpmassDown massCrew Time IP 32S33SSPX-2SPX-2 Descent NomRes 3280Add BRIC-17 to SPX2 for I33/34OPEN N 3287 Vessel ID crew time removal Inc33/34OPEN -0.5 E 3291 Addition of CCF re-run in Increment 33/34OPEN 6.5 N 3293 Inc29/30-31/32-33/34 CIRC/SHD updateOPEN E 3298 Inc33/34 ESA replanning according to new SpX flight programmeOPEN E Total Requirement change

Page No. 8 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Cold Stowage Summary Cold Stowage built a plan based on the draft inputs to the re-planning effort Based on the expanded Sp-X capabilities and the current flight program CR (flight dates), all CS items can be accommodated. Shelf-life data in the back-up slides are based on data from cold stowage forms When are MELFIs full if return capability continues to slide to the right? –MELFI-1 (in JEM) is full by April –MELFI-3 (in Lab) is full by September 2012.

Page No. 9 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Research Objectives and Highlights AgencyResearch Objectives # of New Investigations # of Continuing Investigations New Research Facilities CSA research activities consist of human life sciences, physical science, educational, and technology development investigations ESA research activities will continue to utilize the research capabilities of the Columbus module, expanding research themes in human research, physical & material sciences, space sciences, and technology development JAXA research activities consist of operations in the Kibo module and exposed facility conducting research in human research, physical & material sciences, biology, space sciences, educational, and technology development NASA managed research emphasizes NASA exploration research and technology development and increases the emphasis on use of the ISS as a National Laboratory BSTC-GSM Nano lab

Page No. 10 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only ESA JAXA Key Biology and Biotechnology Cell Bio I-STAR: Microbial Growth Comm. 2 Micro 5, 7, 8 Nanorack Modules NLP-Vaccine 18, 21 AMS-02 CEO HREP HICO HSI I-SERV ISSAC SAMS DOSIS-3D SOLAR/SOLACES & SOLSPEC MAXI MCE SEDA-AP SMILES Earth & Space Science EarthKAM EPO-Demos CSI-06 NLO Education -4 SPHERES Zero Robotics ISS Ham Radio Educational Activities Human Research ELITE-S2 Functional Task Test Intervertebral Disc Damage Manual Control Treadmill Kinematics Cartilage NEUROSPAT Reversible Figures Visual/Cognitive Neural/Muscular Integrated Cardiovascular VO2Max Biological Rhythms 48hrs VC-Reflex Vessel Imaging Cardio-Pulmonary Journals Reaction Self Test Space Headaches Psychology & Cognitive Performance Bisphosphonates Nutrition Repository Nutrient Uptake & Stability, Metabolism, Immune Pro K Circadian Rhythms ENERGY Thermolab Physical and Material Sciences ACE-1 BCAT-3, 4, 5, 6 CFE2 DECLIC DSI-R DECLIC HTI-R FLEX-2 In-SPACE 3 MFMG Space DRUMS BCAT-C1 Dynamic Surf Hicari Ice Crystal-2 JAXA PCG Marangoni UVP Nano Step EML MSL Batch 2A Seedling Growth-1 T-Cell Activation in Aging Viable ISS AQH microscope c/o Medaka Osteoclast Stem Cells EXPOSE-R2 Other/Multiple Hair, Sprint, UMS, EDOS, SPIN, CUSat DOD SPHERES Rings DTN HiMassSEE HREP RAIDS MISSE 8 Nanolab Technology Development Technology Development Area PADLES On-board Diag. 2 TEM for Orb 1 Vessel ID Microflow 1 MVIS Controller RADI-N2 NASA CSA Increments 33 & 34 Research Plan - Investigation List JAXA EPO 10 JAXA Commercial Tomatosphere-III Comm & Outreach-2: (AuroraMax, ARISS, podcasts) NPO Dev. 3, 4 Robonaut Robotic Refueling SCAN Testbed SPHERES Commercial SPHERES Vertigo STP-H3 PPOD Deployables from SpaceX Trunk Other NASA Support

Page No. 11 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only 11 Increments 33 & 34 Experiment Locations HREP-HICO RAIDS SMILES SEDA-AP MAXI MCE - Principal location for each experiment - Racks and Facilities in bold text Facility Acronyms CIR - Combustion Integrated Rack EDR - European Drawer Rack EMCS - European Modular Cultivation System EPM - European Physiology Module FIR – Fluids Integrated Rack FSL – Fluid Sciences Lab HRF – Human Research Facility MARES – Muscle Atrophy Research and Ex Sys MELFI – Minus Eighty deg. Laboratory Freezer MSG – Microgravity Sciences Glove box MSPR – Multi purpose Small Payload Rack MSRR - Materials Science Research Rack WORF - Window Observation Research Facility MSG InSpace-3, Destiny EXPRESS Rack-1 DTN, CGBA-4 / NLP Vaccine-21, Micro-5, CGBA-6 / CSI-06, MAMS, SAMS-II EXPRESS Rack-2A DTN, CGBA-5/Micro-5, GLACIER CIR MDCA-FLEX-2 MSRR/MSL WORF EarthKAM, HSI, ISERV, ISSAC, NPO Dev-3 FIR LMM-ACE-1 MELFI-3 CEO, CFE-2, Cell Bio, Comm & Outreach/Aurora Max, Podcasts. Education-4, EPO Demos, HiMassSEE, ISTAR Comm-2, MFMG, Microbial Growth, Microflow, NPO Dev-4, RADI-N2, Robonaut, Thermolab, Treadmill Kinematics, Tomatosphere, VO2max CETSOL-2, MICAST-2 ELC4 ELC2MISSE 8 S3Truss – AMS-02 Robotic Refueling EXPRESS Rack-8 CGBA-2 / NLP Vaccine-18, Micro-7 & 8 EXPRESS Rack-5 SpaceDRUMS RYUTAI Dynamic Surf, Ice Crystal2, Marangoni, PCG, Nano Step EXPRESS Rack-4 DECLIC, NanoRacks MELFI-1 Stem Cells SAIBO MELFI-2 KIBO MSPR Aquatic Habitat / Medaka Osteoclast Kobairo Hicari Area PADLES, BCAT (3, 4, 5, 6), BCAT-C1, Bio Rhythms CFE-2, Commercial for 33&34 ELITE-S2, Hair, JAXA- EPO, ODK2, RADI-N2, SPHERES/RINGS, Commercial, VERTIGO, Zero Robotics, TEM EDR / EML T-Cell Activation In Aging BioLab HRF-1 Int. Cardiovascular Sprint Vessel Imaging HRF-2 ENERGY, Nutrition, Pro K Repository, EXPRESS Rack 3A EMCS Seedling Growth-1 EPM DOSIS-3D, NEUROSPAT MARES Columbus Bisphosphonates, Circadian Rhythms, Comm & Outreach/ARISS, ISS Ham, Journals Vessel ID Solar RADI-N2, Reaction Self Test, Reversible Figures Space Headaches, Vessel ID PPOD Deployables, CuSAT SpaceX Trunk Extension Express Rack-6 AMS Laptop, GLACIER EXPRESS Rack 7 BSTC/GSM ELC3 STP-H3 SCAN ELC1 VIABLE FGB EXPOSE-R2 SM FSL MVIS Controller 1

Page No. 12 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Increment Concerns Crew time threats: –High Rate Comm System (HRCS) upgrades Cable routing – ~54 hours (plan to perform in I 30) iPEHG – ~7 hours + time for checkout (will plan to perform I 31/32) Ku upgrade (ICU) – ~40 hours (recently added to I 33/34 IDRD) Stability of SpaceX and Orbital flights will be better understood after we begin launching

Page No. 13 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Back-up

Page No. 14 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only

Page No. 15 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Cold Stowage Shelf Life PayloadShelf Life requirementLimited life date Scheduled return Comments JAXA 2DNT-2Complete ops by 12/16/12; Return by post-ops plus 5 months. NLT 5/16/1228S (3/16/12) ESA SOLO, CARDReturn by post-ops plus 1 year 28S ESA ROALDNo limited life identifiedN/A28S HRP Nutrition/Pro K BloodReturn by post-ops plus 1 year Three sessions - Aug /4/12SpX-1 One session - Sept /1/12 Four sessions - Oct /4/12 Four sessions - Jan 2012 Jan-13 Two sessions - Feb 2012 Feb-13 Two sessions - April 2012 Apr-13 Two sessions - April 2012 Apr-13SpX-2 One session - May 2012 May-13 Six sessions - June 2012 Jun-13 Three sessions - July 2012 Jul-13 Three sessions - Sept 2012 Sep-13 Two sessions - Oct Oct-13 Three sessions - Nov 2012 Nov-13 Four sessions - Dec 2012 Dec-13 Three sessions - Jan 2013 Jan-14 Three sessions - March 2013 Mar-14SpX-3 Two sessions - April 2013 Apr-14 Three sessions - May 2013 May-14 Two sessions - June 2013 Jun-14 Three sessions - July 2013 Jul-14 Two sessions - August 2013 Aug-14 HRP Nutrition/Pro K UrineNo limited life identifiedN/A

Page No. 16 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Cold Stowage Shelf Life p.2 PayloadShelf Life requirementLimited life date Scheduled return Comments JAXA HairReturn by post-ops plus 2 years JAXA OK to extend limited life date if frozen temps maintained One 26S crew sample taken 8/24/11 8/24/13SpX-1 Two 27S crew samples taken 10/28/11 10/28/13 Two 29S crew samples One 31S crew sample SpX-2 JAXA CsPINSReturn by post-ops plus 1 year7/15/12SpX-1 Plant SignalingReturn by post-ops plus 1 year8/8/12SpX-1launched on ULF-7 CSA VascularReturn by post-ops plus 2 years10/18/13SpX-1launched on 43P SpX-2no pre-OPS limited life JAXA MycoReturn by post-ops plus 3 years9/22/14SpX-1 JAXA Microbe-IIINo pre-OPS limited life SpX-1 Return Bag #1 & #4Return by post-OPS plus 6 mos Return Bag #2 & #3Return by post-OPS plus 7 days 10 Air FiltersReturn by post-ops plus 1 year JAXA Resist Tubule Run #2No issue because “crossover"N/ASpX-1launch on SpX-1 ESA IMMUNO, SOLO, CARDReturn by post-ops plus 1 year 30S (9/12/12)

Page No. 17 ISS_CM_019 (Rev 09/2011) Pre-decisional, For Internal Use Only Cold Stowage Shelf Life p.3 PayloadShelf Life requirementLimited life date Scheduled return Comments JAXA Stem CellsReturn 1 Bio Dos 13 mos after launch Return 5 Stem Cells 4 yrs after launch SpX-2launch on SpX-2; Stem Cells planned return: 1 as crossover, 1 at 6 mos, 1 at 12 mos, 1 at 24 mos, 1 at 36 mos. but are viable for 4 yrs. JAXA Medaka-OTBD SpX-2launch on HTV-3; Operations begin after 32S (9/2012) (live fish) T-Cells in AgingNo issue because “crossover"N/ASpX-2launch on SpX-2 JAXA Resist Tubule Run #3Perform experiment within 1 yr.; Return by post-OPS plus 3 mos. SpX-3launch on SpX-1 JAXA Cell MechanosensingFor SpX-3 - no issue because “crossover" For SpX-4, return by post-ops plus 1 month SpX-3 & SpX- 4 launch on SpX-3; no pre-ops shelf life identified. Seedling GrowthNo limited life identifiedN/ASpX-3launch on SpX-2 yellow indicates operations not performed12/8/2011