Therapeutic Treatment of Resveratrol on Alzheimer’s Disease with CL2006 Bradford Greaves

Need Figure 1 Figure 2

Alzheimer’s Disease BDD7- A0DF216DAAA4/0/Alzheimers_Disease_Unraveling_the _Mystery.pdf Figure 1 Figure 2 Figure 3 Figure 1

Alzheimer’s Disease cont.

Oxidative Damage

Literature Review Resveratrol Promotes Clearance of Alzheimer’s Disease Amyloid- Peptides, Marambaud 2005 Transgenic C. elegans as a Model in Alzheimer’s Research, Wu 2005

Purpose To preventatively and therapeutically treat Alzheimer’s Disease with resveratrol using CL2006 and CL4176 C. elegan models

Hypothesis Alternate Hypothesis: Both preventive and therapeutic treatment of resveratrol on CL2006 will lead to a decrease in amyloid beta production and for CL4176 there will be a delay of the onset of paralysis. Null Hypothesis: There will be no change in amyloid beta production nor paralysis with the addition of resveratrol.

Resveratrol’s Coloration With Alzheimer’s Disease

Resveratrol’s Role

The APP Processing Senile Plaques Modified from Laurén et al., Nature (2009)

Overview of Methodology

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