Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / Panel (a) displays PC3 data from [12], while panel (b) shows CHO data from [13]. The PC3 data are for heating from 44≤T≤56 °C. Data are taken for up to 30 mins of heating. Panel (b) is for heating from 43.5≤T≤46.5 °C, with heating of up to 105 mins. Note that the dotted lines are not model results, but meant as a visual aid. Figure Legend:

Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / The PC3 data fit by the models (a) first-order, (b) Johnson and Pavelec, (c) Kellerer and Rossi, (d) Jung, (e) Mackey and Roti Roti, and (f) Feng et al. The circles represent 44 °C, the squares 46 °C, the diamonds represent 48 °C, the triangles 50 °C, and the inverted triangles 54 °C. The 56 °C data were not used. The 56 °C data were not used. Figure Legend:

Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / The difference between the measured and predicted survival are shown in the residuals (S-S ∧ ). For the predictions of the PC3 cells heated at 48 °C these are for the first-order model (solid circle), Johnson and Pavelec model (solid square), Kellerer and Rossi (solid triangle), Jung model (open circle), Mackey and Roti Roti model (open square), and Feng et al. model (open triangle). Figure Legend:

Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / Scaled sensitivity coefficients of the (a) first-order model (k–dashed), (b) Johnson and Pavelec model (kj–dashed, nj–dot-dash), (c) Kellerer and Rossi model (ak–dashed, bk–dot-dash), (d) Jung model (p–dashed, c–dot-dash), (e) Mackey and Roti Roti model ( ɛ f– dashed, kr–dot-dash), and (f) Feng et al. model (α–dashed, β–dot-dash, γ–dotted) for PC3 cells heated at 48 °C. The solid line in each panel is the model prediction for S at 48 °C, for reference. Figure Legend:

Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / The CHO data fit by the models (a) first-order, (b) Johnson and Pavelec, (c) Kellerer and Rossi, (d) Jung, (e) Mackey and Roti Roti, and (f) Feng et al. The solid circles represent 43.5 °C, the solid squares 44 °C, the diamonds represent 44.5 °C, the triangles 45 °C, the inverted triangles 45.5 °C, the open circles 46 °C, and the open squares 46.5 °C. Figure Legend:

Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / The difference between the measured and predicted survival are shown in the residuals (S-S ∧ ) for the CHO cells at 45 °C. The residual are for the the first-order model (solid circle), Johnson and Pavelec model (solid square), Kellerer and Rossi (solid triangle), Jung model (open circle), Mackey and Roti Roti model (open square), and Feng et al. model (open triangle). Figure Legend:

Date of download: 5/27/2016 Copyright © ASME. All rights reserved. From: Comparison of Models of Post-Hyperthermia Cell Survival J Biomech Eng. 2013;135(5): doi: / Scaled sensitivity coefficients of the (a) first-order model (k–dashed), (b) Johnson and Pavelec model (kj–dashed, nj–dot-dash), (c) Kellerer and Rossi model (ak–dashed, bk–dot-dash), (d) Jung model (p–dashed, c–dot-dash), (e) Mackey and Roti Roti model ( ɛ f– dashed, kr–dot-dash), and (f) Feng et al. model (α–dashed, β–dot-dash, γ–dotted) for CHO cells heated at 45 °C. The solid line in each panel is the model prediction for S at 45 °C, for reference. Figure Legend: