128/02/2011 Confidential Who is Alcimed ? ALCIMED is a European consulting company specialized in Life Sciences/Healthcare and Chemicals, founded in 1993 by three graduates from the ’Ecole Centrale de Paris’, with current offices in France, Germany and Switzerland. ALCIMED helps decision-makers to make the right strategic decisions in terms of product positioning and development, assists them in grasping opportunities (new targets, emerging needs, cutting-edge technology, new product concepts) and in adapting to threats (changes in regulatory environments, emergence of new competitors, generic threats, etc.). ALCIMED works for a variety of clients, including over 100 companies within the (bio-)pharmaceutical and medical device industry, as well as with biotechnology, food, chemicals and cosmetics industry players. The company also works for a number of European / National institutions. Our areas of expertise are R&D & IO, Marketing & Sales, and Corporate Affairs & Market Access. ALCIMED’s team is remarkable for its culture of wide-ranging general expertise (scientific / technical / medical / business) and its high standards of education and training: over 160 highly-qualified consultants, graduated from top-level European Universities, scientists in the fields of biology, chemistry, physics and technology, most of whom having further training in marketing, business, strategy, or IT. Complex markets analysis Positioning of products/portfolio Elaboration of strategies towards stakeholders Commercial strategy and value proposition strategy Optimization of mix marketing and promotion Strategies in view of opportunities and threats Market access strategy and landscape assessment Stakeholder management and negotiation with payers Pricing & Reimbursement analysis R&D / IO Corporate & Market Access Corporate & Market Access Marketing & Sales Assessment of new technologies / research areas Product development strategies Optimization of R&D / IO organization and operations Funding dossiers and project management

228/02/2011 Confidential ALCIMED helps decision-makers to identify the right strategic choices:  Support them for product positioning and development  Assist them in grasping opportunities (new targets, emerging needs, cutting-edge technology etc)  Help them adapt to threats (changes in regulatory environments, emergence of new competitors, generic threats, etc) ALCIMED helps decision-makers to identify the right strategic choices:  Support them for product positioning and development  Assist them in grasping opportunities (new targets, emerging needs, cutting-edge technology etc)  Help them adapt to threats (changes in regulatory environments, emergence of new competitors, generic threats, etc) Created in 1993, ALCIMED is a very dynamic company:  ALCIMED has been developing its activities at an average growth rate of about 20 to 30 % per year, in the past 12 years  5 offices located in France (Global HQ in Paris), Germany, and Switzerland  In the process of opening new ones in Belgium, the UK and notably in New Jersey for its US clients Created in 1993, ALCIMED is a very dynamic company:  ALCIMED has been developing its activities at an average growth rate of about 20 to 30 % per year, in the past 12 years  5 offices located in France (Global HQ in Paris), Germany, and Switzerland  In the process of opening new ones in Belgium, the UK and notably in New Jersey for its US clients ALCIMED’s expertise is about innovation, where science and business meet:  Over 15 years of Life Sciences and Chemical business experience, in three main geographical zones: Europe, North America and Emerging Countries  Our range of services encompasses Marketing & Sales, Corporate & Market Access, and R&D  ALCIMED performed 450 assignments in 2009 for over 100 pharmaceutical and biopharmaceutical firms and a number of European institutions ALCIMED’s expertise is about innovation, where science and business meet:  Over 15 years of Life Sciences and Chemical business experience, in three main geographical zones: Europe, North America and Emerging Countries  Our range of services encompasses Marketing & Sales, Corporate & Market Access, and R&D  ALCIMED performed 450 assignments in 2009 for over 100 pharmaceutical and biopharmaceutical firms and a number of European institutions Who is Alcimed ? A consulting firm at the interface of science and business A dynamic and fast-growing company A consulting firm specialized in decision support