TUMOR BURDEN ANALYSIS ON CT BY AUTOMATED LIVER AND TUMOR SEGMENTATION RAMSHEEJA.RR Roll : No 19 Guide SREERAJ.R ( Head Of Department, CSE)

OBJECTIVE  Aim to the developments of the technique to constitute a computer-aided system for the fully automated integrated analysis of the liver  Study various methods of liver cancer detection  Develope a method to detect liver cancer in early

INTRODUCTION  Liver has many important functions  Liver cancer is 4 th most common malignancy in the world  Computed Tomography (CT) scans are a common tool for diagnosis

PROBLEM STATEMENT  Liver Segmentation is an important first step for Computer- Aided Diagnosis (CAD)  Difficulties associated with liver segmentation  Time consuming  Similarities to other organs

ADVANTAGES - AUTOMATED METHODS  The reproducibility of results  Not subjected to user interaction  Faster  Readily available  Reduce errors

iInput image Preprocessing Liver tumor segmentation Liver segmentation Classification Feature extraction Normal Abnormal SYSTEM ARCHITECTURE

LIVER SEGMENTATION[5] [3]A. M. Mharib, A. R. Ramli, S. Mashohor, R. B. Mahmood, “Survey on Liver CT image Segmentation Methods” in Artif Intell Rev 37: pp Springer  Segmentation techniques which are mainly automatic in nature.  Liver image segmentation techniques can be divided in two classes  semi-automatic  fully automatic methods  Graph Cuts segmentation algorithm is used

SEGMENTATION WITH GRAPH CUT

FEATURE EXTRACTION[4] [4]Statistical Texture Measures Computed from Gray Level Coocurrence Matrices Fritz Albregtsen Image Processing Laboratory Department of Informatics University of Oslo November 5, 2008  For feature extraction here use The GLCM Algorithm  Gray Level Co-occurrence Matrix  Way of extracting second order statistical texture features Energy, Entropy, Contrast, Homogeneity Correlation

FEATURE CLASSIFICATION[5]  Use Support Vector Machine (SVM)classifier  Binary classifier  Machine Learning Algorithm  Predict about the features  To improve classification SVM is trained by using weighted features for data classification [5]K. Kramer, L. Hall, D. Goldgof, “Fast Support Vector Machines for Continuous Data,” IEEE Transactions on Systems, Man and Cybernatics, vol. 39, no. 4, pp , 2009.

LIVER TUMOR SEGMENTATION[6]  An efficient fuzzy c-mean based segmentation algorithm to extract tumor region  FCM is a soft segmentation method which retains more information from input image than hard segmentation methods  Efficient than existing segmentation methods  To improve segmentation we can use Enhanced FCM [6]a International Journal of Computer Applications (0975 – 8887) Volume 59– No.5, December Performance Improvement of Fuzzy C-mean Algorithm for Tumor Extraction in MR Brain Images

CONCLUSION  The automated segmentation of liver is addressed first  Here segment the tumor and classifies about the image  The technique is improved significantly and the segmentation of large tumor  Reduce the number of false tumor detection

REFERENCES [1] D. Shen,W.Wong, and H.S.H. Ip, “Affine-invariant image retrieval by correspondence matching of shapes,”Image and Vision Computing, vol. 17, pp. 489– 499,1999. [2] Y. Boykov and V. Kolmogorov, “An experimental comparison of mincut/max- flow algorithms for energy minimization in vision,” IEEE Trans. Pattern Anal. Mach. Intell., vol. 26, no. 9, pp. 1124–1137, Sep.2004 [3] P. Campadelli, E. Casiraghi, and A. Esposito, “Liver segmentation from computed tomography scans: A survey and a new algorithm,”Artif. Intell. Med., vol. 45, pp. 185– 196, [4] Shawn Lankton, Allen Tannenbaum “Localizing Region-Based Active Contours” IEEE TRANSACTIONS ON IMAGE PROCESSING, VOL. 17, NO. 11, NOVEMBER Published in final edited form as:IEEE Trans Image Process November; 17(11): 2029–2039.

REFERENCES [5]A. M. Mharib, A. R. Ramli, S. Mashohor, R. B. Mahmood, “Survey on Liver CT image Segmentation Methods” in Artif Intell Rev 37: pp Springer [6] Yueyi I. Liu “Bayesian classifier for differentiating malignant and benign nodules using sonography features” AMIA 2008 symposium proceeding page [7] M. Mignotte. Segmentation by fusion of histogram-based k-means clusters in different color spaces. IEEE Transactions on Image Pro- cessing, 17(5):780–787, [8] S. Jagannath et al., “Tumor burden assessment and its implication for a prognostic model in advanced diffuse large-cell lymphoma,” J. Clin. Oncol., vol. 4, no. 6, pp. 859–865, [9] Viet Dzung Nguyen, DucThuan Nguyen, TienDzung Nguyen and Van Thanh Pham,“An automated method to segment and classify masses in mammograms”,International Journal of Computer and Information Engineering, 52, 2009

THANK YOU