 Tobacco use is the major risk factor, followed by alcohol (cofactor)  Emerging role of HPV  Nasopharyngeal tumors are associated with EBV infection

 Non-healing ulcer  Lose teeth or dentures, haliotosis  Trismus, odynophagia, dysphagia, sore throat  Hoarse, “hot potato voice”  Hemoptysis, hemetemesis, epistaxis  Nasal obstruction, otalgia, serous OM, cranial neuropathy  Neck mass  Weight loss

 Laryngeal & Hypopharyngeal  Nasal Cavity & Paranasal Sinuses  Nasopharyngeal Cancer  Oral & oropharyngeal Cancer  Salivary Gland Cancer

 62,000…45,000 males & rest females  13,000 Deaths

 Tobacco  Alcohol  HPV  EBV for Nasopharyngeal  >40 years of age  Males > female  Inhalents, Poor oral hygiene, Black Race, Marijuana

 Swelling or Sore that does not heal…most common  Red or White Patch in Mouth  Lump, Bump or Mass in Head & Neck area with or without pain  Sore throat that does not resolve  Halitosis  Hoarseness or Nasal Congestion  Nosebleeds  Numbness in Head and Neck Area  Pain moving jaw, chewing & swallowing

 Biopsy  HPV  Endoscopy…Usually Panendoscopy  Barium Swallow  Panorex  US, CT, MRI, Bone Scan, PET Scan

 Surgery  Surgery followed by Radiation & Chemo  Surgery followed by Radiation  Radiation & Chemotherapy