Lecture 10 – Protein Function Based on Chapter 04 - Gene Function Copyright © 2010 Pearson Education Inc. Questions to answer in this chapter: What is.

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Lecture 10 – Protein Function Based on Chapter 04 - Gene Function Copyright © 2010 Pearson Education Inc. Questions to answer in this chapter: What is the relationship between genes and enzymes? How do genes control biochemical pathways? What is the relationship between genes and nonenzymatic proteins? How can people be tested for a genetic disease mutation?

1. Gene Control of Enzyme Structure

3b. One-Gene–One-Enzyme Hypothesis

4. Genetic Dissection of a Biochemical Pathway

5. Genetically Based Enzyme Deficiencies in Humans

6. Phenylketonuria 7. Albinism 8. Kartagener Syndrome

9. Tay–Sachs Disease

10. Gene Control of Protein Structure

11a. Sickle-Cell Anemia

11b. Sickle-Cell Anemia

11c. Sickle-Cell Anemia

12. Other Hemoglobin Mutants

Biochemical Genetics of Human Blood Type Peter J. Russell, iGenetics: Copyright © Pearson Education, Inc., publishing as Benjamin Cummings.

Biochemical Genetics of Human Blood Type Peter J. Russell, iGenetics: Copyright © Pearson Education, Inc., publishing as Benjamin Cummings. Antigenic reactions that characterize the human ABO blood types

13a. Cystic Fibrosis

13b. Cystic Fibrosis