Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease by Marilyn J. Telen Blood Volume 127(7):810-819 February 18, 2016 ©2016 by.

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Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease by Marilyn J. Telen Blood Volume 127(7): February 18, 2016 ©2016 by American Society of Hematology

The sickle red blood cell (SS RBC) as source of multiple pathophysiologic pathways. Marilyn J. Telen Blood 2016;127: ©2016 by American Society of Hematology

Adhesive interactions involving SS RBCs. (A) Multiple interactions between SS RBCs and endothelial cells, extracellular matrix, and plasma proteins. Marilyn J. Telen Blood 2016;127: ©2016 by American Society of Hematology