서울대학교 차세대 기계항공시스템 창의설계 인력양성사업단 기계항공공학부 차세대 기계항공시스템 창의설계 인력양성사업단 1. 연 사 : Prof. Peter M. Pinsky Department of Mechanical Engineering, Stanford University, Stanford, CA 2. 제 목 : A nonlinear multiphasic model for describing interactions between solid, fluid and ionic species in biological tissue 3. 일 시 : 2010 년 8 월 9 일 ( 월 ) 오후 2:00-3:30 4. 장 소 : 301 동 호 5. 내 용 : Multiphysics problems describing electro-chemical-fluid-solid interactions arise for porous media such as rocks, soils, foams, ceramics and biological tissues. In this talk we review a new model for quasistatic finite deformation of swelling incompressible porous media derived from mixture theory. The model describes an electrically charged porous solid saturated with a monovalent ionic solution. Solid, fluid, anion and cation phases are defined and balance laws for each phase and for the mixture as a whole are derived. As an example, we turn to connective tissue in which the solid phase is negatively charged by the presence of glycosaminoglycan (GAG) molecules and the ionic concentration gradient can generate significant osmotic pressure. An analysis of the swelling of human cornea under a shock of NaCl hypertonic solution is presented. We also show through a molecular-level analysis that the electrostatic interaction between GAGs and free ions controls the collagen interfibril spacing and thereby maintains the transparency of the tissue. 6. 약 력 : Dr. Pinsky holds a B.Sc. degree from the University of Wales, Swansea, an M.A.Sc. degree from the University of Toronto, and a Ph.D. from the University of California at Berkeley, all in the field of Civil Engineering. He is a Professor of Mechanical Engineering and serves as Chairman of the Division of Mechanics and Computation. He is a member of Stanford’s Institute for Computational and Mathematical Engineering and is, by courtesy, a Professor of Civil and Environmental Engineering. His research specialization is in computational aspects of solid and structural mechanics with a particular interest in the finite element method for nonlinear and dynamical problems, including computational biomechanics, structural acoustics, and multiscale modeling of material behavior. 7. 문 의 : 기계항공공학부 조맹효 교수 ( ☏ )

서울대학교 차세대 기계항공시스템 창의설계 인력양성사업단 기계항공공학부 차세대 기계항공시스템 창의설계 인력양성사업단 1. 연 사 : Prof. Peter M. Pinsky Department of Mechanical Engineering, Stanford University, Stanford, CA 2. 제 목 : Measuring and modeling the elasticity of the living human cornea 3. 일 시 : 2010 년 8 월 10 일 ( 화 ) 오후 2:00-3:30 4. 장 소 : 301 동 호 5. 내 용 : The dimensional stability of the cornea is directly attributable to the composition and structure of the extracellular matrix of the stroma, the connective tissue layer that comprises most of the cornea’s thickness and which is made up of several hundred superimposed stromal lamellae. In this talk we review a new nearly incompressible hyperelastic constitutive model for the stroma and describe experiments for characterizing the mechanical properties. The model employs an averaging theory applied to a representative lamella in which the probability of collagen orientation, as measured by x-ray scattering, is used as weighting. In order to identify the model parameters we have completed in vivo mechanical testing by measuring the contours of a human cornea deformed in situ by a mechanical probe and in vitro by direct measurement of shear stiffness. An application to laser eye surgery (LASIK) is described. 6. 약 력 : Dr. Pinsky holds a B.Sc. degree from the University of Wales, Swansea, an M.A.Sc. degree from the University of Toronto, and a Ph.D. from the University of California at Berkeley, all in the field of Civil Engineering. He is a Professor of Mechanical Engineering and serves as Chairman of the Division of Mechanics and Computation. He is a member of Stanford’s Institute for Computational and Mathematical Engineering and is, by courtesy, a Professor of Civil and Environmental Engineering. His research specialization is in computational aspects of solid and structural mechanics with a particular interest in the finite element method for nonlinear and dynamical problems, including computational biomechanics, structural acoustics, and multiscale modeling of material behavior. 7. 문 의 : 기계항공공학부 조맹효 교수 ( ☏ )