Human Genetics Integrative Bioinformatics using Cytoscape (and R2)

Human Genetics External data sources Statistical analysis Perl module AMC Plugin Canonical paths DB Patient data GEO arrays Wet-lab data Algorithms Data input interface Array data: Tumor and time series R2-array analysis interface Cytoscape interface

Human Genetics

Tf (green) and partners (red)

Human Genetics Filtering

Human Genetics Filtering

Human Genetics Coloring, layout

Human Genetics Tf and partners

Human Genetics Availability R2 –Available shortly through –Keep yourself posted on

Human Genetics Acknowledgements Department of Human Genetics - Academic Medical Center Piet Molenaar Jan Koster Richard Volckmann Rogier Versteeg NBIC-Biorange programme Cytoscape community Cytoscape Consortium –UC San Diego –Institute for Systems Biology –Memorial Sloan-Kettering Cancer Center –Agilent Technologies –Unilever –UC San Francisco –University of Toronto –Institut Pasteur Any questions later on:

Human Genetics

Timeseries in R2

Human Genetics

Not only multiplo

Human Genetics

Network inference: TF and GO analysis

Human Genetics