Fluids & Electolytes Pharmacology Review 9 June :16 AM

Acebutolol Sympatholytic  1 adrenergic antagonist Class II antiarrhythmic Antihypertensive Antianginal Bronchoconstrictor

Acetazolamide Diuretic Carbonic anhydrase inhibitor

Alendronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

Amikacin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Amiloride Potassium sparing diuretic Sodium channel inhibitor Antihypertensive

Aminoglycosides Antibiotics Bactericidal protein synthesis inhibitors 30S ribosome Freeze initiation

Amlodipine Antihypertensive Calcium channel blocker

Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking

Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking

Atenolol Sympatholytic  1 adrenergic antagonist Antihypertensive Antiarrhythmic Antianginal Bronchoconstrictor

Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

Aztreonam New  lactam antibiotic Monobactam

Bacitracin Antibiotic Cell wall synthesis inhibitor Topical, not a  lactam, Inhibits dephosphorylation of bactoprenol

Benazopril Antihypertensive Converting enzyme inhibitor

Benzathine penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Inhibits peptidoglycan cross-linking Repository preparation

Betaxolol Sympatholytic  1 adrenergic antagonist Antihypertensive Glaucoma medication Bronchoconstrictor

Bretylium Sympatholytic Class III antiarrhythmic K + channel blocker

Bumetanide Loop diuretic Na + -K + -2Cl - transporter inhibitor

Captopril Antihypertensive Converting enzyme inhibitor Heart failure treatment Angioedema producer

Carbenicillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

Carteolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

Cefaclor Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation Oral

Cefadroxil Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

Cefepime Cephalosporin antibiotic Cell wall synthesis inhibitor 4 th generation CSF penetration

Cefotaxime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration

Cefoxitin Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation

Ceftazidime Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation

Ceftriaxone Cephalosporin antibiotic Cell wall synthesis inhibitor 3 rd generation CSF penetration

Cefuroxime Cephalosporin antibiotic Cell wall synthesis inhibitor 2 nd generation CSF penetration

Cephalexin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

Cephalosporins Antibiotics  lactam Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

Cephalothin Cephalosporin antibiotic Cell wall synthesis inhibitor 1 st generation Oral

Chloramphenicol Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits peptide bond formation

Chlorthalidone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

Chlorothiazide Thiazide diuretic Na-Cl symporter inhibitor

Ciprofloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation

Clavulanic acid  -lactamase inhibitor Combined with antibacterials

Clindamycin Antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Anaerobic infections

Clonidine Sympatholytic  2 adrenergic agonist Antihypertensive

Cloxacillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

Cycloserine Antibiotic Cell wall synthesis inhibitor Secondary TB drug Inhibits formation of Park nucleotide

Dapsone Sulfone antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Leprosy

Desmopressin acetate Synthetic analogue of arginine vasopressin Used in treatment of bleeding disorders

Diazoxide Vasodilator Antihypertensive

Diltiazem Class IV antiarrhythmic Antihypertensive Ca 2+ channel blocker

Doxazosin Sympatholytic  1 adrenergic antagonist Antihypertensive

Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Enalapril Antihypertensive Converting enzyme inhibitor Angioedema producer

Eplerenone Aldosterone receptor antagonist

Eprosartan Antihypertensive Angiotensin receptor blocker (ARB)

Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

Esmolol Sympatholytic  1 adrenergic antagonist Class II Antiarrhythmic Antihypertensive Bronchoconstrictor

Ethacrynic acid Loop diuretic Na-K-2Cl symporter inhibitor

Etidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

Felodipine Antihypertensive Calcium channel blocker

Fluorinated Quinolones ciprofloxacin, norfloxacin Antibiotics DNA replication inhibitors Inhibit bacterial DNA gyrase

Fosinopril Antihypertensive Converting enzyme inhibitor

Furosemide Loop diuretic Na-K-2Cl symporter inhibitor Antihypertensive

Gentamicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Guanabenz Sympatholytic Antihypertensive

Guanadrel Sympatholytic Antihypertensive

Guanethidine Sympatholytic Antihypertensive

Guanfacine Sympatholytic  2 adrenergic agonist Antihypertensive

Hydralazine Vasodilator Antihypertensive

Hydrochlorothiazide Thiazide diuretic Na-Cl symporter inhibitor Antihypertensive

Imipenem/Cilastatin New  lactam antibiotic Cilastatin inhibits a kidney dipeptidase that inactivates imipenem

Indapamide Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

Irbesartan Antihypertensive Angiotensin receptor blocker (ARB)

Isradipine Antihypertensive Calcium channel blocker

Labetalol Sympatholytic  and  adrenergic antagonist Antihypertensive

Linezolid Oxazolidinone antibiotic Protein synthesis inhibitor 50S ribosomal subunit

Losartan Antihypertensive Angiotensin receptor blocker (ARB)

Lypressin Antidiuretic hormone analogue

Macrolides erythromycin, azithromycin, clarithromycin Antibiotics Bacteriostatic protein synthesis inhibitors 50S ribosome

Mannitol Osmotic diuretic

Methenamine Urinary tract antiseptic Decomposes to formaldehyde in acidic environment

Methicillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

Methydopa Sympatholytic  2 adrenergic agonist Antihypertensive

Metolazone Thiazide-like diuretic Na-Cl symporter inhibitor Antihypertensive

Metoprolol Sympatholytic  1 adrenergic antagonist Antihypertensive Heart failure medication Bronchoconstrictor

Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Minoxidil Vasodilator Antihypertensive

Nadolol Sympatholytic  adrenergic antagonist Antihypertensive

Nafcillin Penicillin antibiotic Cell wall synthesis inhibitor Penicillinase resistant penicillin Inhibits peptidoglycan cross-linking

Nalidixic acid Urinary tract antiseptic Quinolone Inhibits bacterial DNA gyrase

Neomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation Topical

Netilmicin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Nicardipine Antihypertensive Calcium channel blocker

Nifedipine Antihypertensive Antianginal Calcium channel blocker

Nisoldipine Antihypertensive Calcium channel blocker

Nitrendipine Antihypertensive Calcium channel blocker

Nitrofurantoin Urinary tract antiseptic Reduction leads to intermediates that damage DNA

Nitroglycerine Venodilator Antianginal

Nitroprusside Vasodilator Antihypertensive

Norfloxacin Fluoroquinolone antibiotic DNA replication inhibitor Inhibits bacterial DNA gyrase

Oxacillin Penicillin antibiotic Cell wall synthesis inhibitor Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Pamidronate Anti-osteoporesis Bisphosphonate Inhibitor of osteoclast-mediated bone resorption

Para-aminosalicylic acid Antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Secondary TB drug

Penbutolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

Penicillins  lactam antibiotics Cell wall synthesis inhibitors Inhibit cross-linking of peptidoglycan

Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Acid labile Inhibits peptidoglycan cross-linking

Penicillin V Penicillin antibiotic Cell wall synthesis inhibitor More acid resistant than Penicillin G Inhibits peptidoglycan cross-linking

Phenoxybenzamine Sympatholytic  adrenergic antagonist Antihypertensive

Phentolamine Sympatholytic  adrenergic antagonist Antihypertensive

Pindolol Sympatholytic  adrenergic antagonist Antihypertensive Bronchoconstrictor

Piperacillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

Polymyxin B Antibiotic Disrupts gram negative cell membrane Binds phosphatidylethanolamine Bactericidal

Prazosin Sympatholytic  1 adrenergic antagonist Antihypertensive

Probenecid Uricosuric Adjunct in penicillin therapy

Procaine Penicillin G Penicillin antibiotic Cell wall synthesis inhibitor Repository preparation Inhibits peptidoglycan cross-linking

Propranolol Sympatholytic  adrenergic antagonist Class II antiarrhythmic Antihypertensive Bronchoconstrictor

Quinapril Antihypertensive Converting enzyme inhibitor

Quinethazone Thiazide-like diuretic Na-Cl symporter inhibitor

Quinopristin/Dalfopristin Streptogramin antibiotic Protein synthesis inhibitor 50S ribosomal subunit

Ramipril Antihypertensive Converting enzyme inhibitor

Reserpine Sympatholytic Antihypertensive

Rifampin Antibiotic Nucleic acid synthesis inhibitor Inhibits DNA dependent RNA polymerase Major drug for TB

Silver sulfadiazine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome

Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment

Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor

Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase

Telmisartan Antihypertensive Angiotensin receptor blocker (ARB)

Terazosin Sympatholytic  1 adrenergic antagonist Antihypertensive Treatment for benign prostatic hypertrophy

Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment

Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

Timolol Sympatholytic  adrenergic antagonist Antihypertensive Glaucoma treatment Anti-anginal Bronchoconstrictor

Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

Tosemide Loop diuretic Na-K-2Cl symporter inhibitor

Triamterene Potassium sparing diuretic Sodium channel inhibitor Antihypertensive

Trimethaphan Sympatholytic Anticholinergic Nicotinic antagonist Antihypertensive

Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Inhibits bacterial dihydrofolate reductase

Valsartan Antihypertensive Angiotensin receptor blocker (ARB)

Vancomycin Antibiotic Inhibits cell wall synthesis Not a  lactam

Arginine vasopressin (Antidiuretic hormone; ADH) Hypothalamic (posterior pituitary) hormone Antidiuretic Vasoconstrictor

Verapamil Class IV antiarrhythmic Antihypertensive L-type Ca 2+ channel blocker Antianginal