The Epidemiology of Idiopathic Pulmonary Fibrosis Vidya Navaratnam University of Nottingham.

Slides:

Advertisements

Similar presentations

Update in ILD: Current Approaches to IPF Andrew M. Tager, M.D.

Advertisements

The Breathing Space Clinic …a multi-disciplinary, inter-organisational hospice-based clinic to support the holistic needs of patients with advanced chronic.

COPD Analyses Updated – 7th February February 2011.

Programme Where are we now? Current PCT performance within SHA No decision about me, without me: Local patients views Are there alternative ways of delivering.

| 1| 1Peer Report: Dialysis Care & Outcomes in the U.S., 2014 | Hospitalization Peer Report: Dialysis Care & Outcomes in the U.S., 2014 Hospitalization.

Idiopathic pulmonary fibrosis (IPF) – The need for early recognition and referral PRC-2128.

Prostate Cancer Craig Blundred. Overview Disease Definition  Epidemiological Classification  Symptoms Disease Burden  Incidence  Mortality  Health.

Alcohol-Related Harm and Unmet Need Amongst Older Drinkers S Wadd, R Driver, D Forrester.

Deaths from smoking in the former Yugoslav Republic of Macedonia.

Deaths from Fracture Neck of Femur. Age standardised Death rate Fracture of Femur age

Deaths from smoking in all developed countries. Deaths from smoking in all developed countries Particular emphasis is given to the number of deaths in.

Deaths from smoking in Serbia and Montenegro. Deaths from smoking in Serbia and Montenegro Particular emphasis is given to the number of deaths in middle.

INTERSTITIAL LUNG DISEASE

CHAPTER 9 Primary Liver Cancer Source: Burden of digestive diseases in the United States, NIH Publication No

Pulmonary Fibrosis and Gradual Onset Breathlessness Dr. Tim Sutherland Consultant with a specialist interest in ILD.

Henrik Møller, Carolynn Gildea, David Meechan, Greg Rubin, Thomas Round, Peter Vedsted Cancer Epidemiology and Population Health, KCL (HM) Public Health.

CHAPTER 5 Cancer of the Esophagus Source: Burden of digestive diseases in the United States, NIH Publication No

IDIOPATHIC PULMONARY FIBROSIS. BASICS in IPF CLASSIFICATION OF INTERSTITIAL LUNG DISEASE OR DIFFUSE PARENCHYMAL LUNG DISEASE.

Statistics about unknown primary tumors Riccardo Capocaccia National Centre for Epidemiology, Surveillance and Health Promotion Istituto Superiore di Sanità,

Idiopathic Pulmonary Fibrosis: Diagnosis and Understanding

Socio-economic inequalities in the pathway of care for pancreatic cancer James Brown, Jean Adams, Martin White & Mark Pearce Institute of Health & Society.

BEST: Beta-blocker Evaluation Survival Trial Purpose To determine whether the β-blocker bucindolol reduces morbidity and mortality in patients with advanced.

Community based integrated intervention for prevention and management of Chronic Obstructive Pulmonary Disease in Guangdong, China: cluster randomised.

JSNA 2012: Summary of Main Findings. Infant mortality trend, England, Yorkshire and Humber and North East Lincolnshire There have been big reductions.

© Cancer Research UK 2002 Registered charity number Figure One: Numbers of new cases and rates by age and sex, brain and other central nervous.

Deaths from smoking in Austria. Deaths from smoking in Austria Particular emphasis is given to the number of deaths in middle age (defined as ages 35.

© Cancer Research UK 2005 Registered charity number Oral Cancer The statistics in this presentation are based on the Oral CancerStats report published.

CHAPTER 11 Cancer of the Gallbladder Source: Burden of digestive diseases in the United States, NIH Publication No

PFF Teal = MAIN COLORS PFF Green = Light Green = Red = HIGHLIGHT COLORS Light Grey = Dark Grey =

PFF Teal = MAIN COLORS PFF Green = Light Green = Red = HIGHLIGHT COLORS Light Grey = Dark Grey =

HOW ARE PRIORITY ISSUES FOR AUSTRALIA’S HEALTH IDENTIFIED? HEALTH PRIORITIES IN AUSTRALIA.

© Cancer Research UK 2002 Registered charity number Cervical Cancer The statistics in this presentation are based on the Cervical CancerStats report.

以多重死因資料比較台灣美國腦中風併發吸入性肺炎之趨勢奇美醫學中心張嘉祐醫師. Stroke Statistics -- A Report From the American Heart Association Approximately 56% of stroke deaths in 2009.

South West Public Health Observatory The work of the South West Public Health Observatory on End of Life care SEPHIG January 2011 Andy Pring.

R1 정수웅.  Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive, fibrosing interstitial pneumonia of unknown cause that occurs.

Trends in prostate cancer and its management in the South West Region, Hampshire and the Isle of Wight Christine Harling Julia Verne (SWPHO) Roy Maxwell.

MERS-CoV (Middle Eastern Respiratory Syndrome) Mike Wade – 16/06/15, updated 23/7/15.

South West Public Health Observatory South West Regional Public Health Group How will the new National End of Life Intelligence Network support commissioning.

Cancer - What’s available from the LHO? David Hofman.

The Registry of the International Society for Heart and Lung Transplantation: Thirty- second Official Adult Lung and Heart-Lung Transplantation Report—2015;

Health …the sedimentation of society

Table 1. Baseline Characteristics of the 36,636 Study Subjects

Survival After Single Versus Bilateral Lung Transplantation for High-Risk Patients With Pulmonary Fibrosis Eric S. Weiss, MD, MPH, Jeremiah G. Allen,

Anastasiia Raievska (Veramed)

Differences in Response to Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease Respiration 2011;81:196–205.

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

Early Clinical Experiences with Nintedanib in 3 Tertiary Interstitial Lung Disease Centres

Lung Cancer in Lewisham

Respiratory MCNs - Interstitial lung diseases

Volume 136, Issue 4, Pages (April 2009)

Joe West, Richard F.A Logan, Tim R Card, Chris Smith, Richard Hubbard

Kaplan–Meier curve for the time until the development of lung cancer in patients with idiopathic pulmonary fibrosis. Kaplan–Meier curve for the time until.

Comparative expression of discoidin domain receptors (DDRs) between healthy lung tissues and those from different types of interstitial lung disease (ILD):

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

Rate of improvement of CF life expectancy exceeds that of general population— Observational death registration study Matthew N. Hurley, Tricia M. McKeever,

Flowchart showing the requirement for starting, documenting and evaluating the effect on quality of life (QoL) of interdisciplinary best supportive care.

Kaplan–Meier survival curves of all-cause mortality in patients with idiopathic pulmonary fibrosis (IPF). Kaplan–Meier survival curves of all-cause mortality.

UK Cystic Fibrosis Registry Annual Data Report 2017

Meena Kalluri, MD, Janice Richman-Eisenstat, MD, FRCPC

UK Renal Registry 16th Annual Report

Time to disease progression or death in a) the whole Bosentan Use in Interstitial Lung Disease (BUILD)-1 study population and b) the subpopulation with.

CUP Incidence UK, 2012 (C77-80) CUP has the 10th highest number of new cancer cases each year in the UK England Wales Scotland N Ireland UK Male 3,730.

BTS ILD Registry Programme: IPF Registry

BTS ILD Registry Programme: IPF Registry

Proportion of participants with access to a, b) a radiologist and c, d) a pathologist experienced in interstitial lung diseases to discuss cases of suspected.

Transcriptomic fingerprint of advanced idiopathic pulmonary fibrosis (IPF) lung. Transcriptomic fingerprint of advanced idiopathic pulmonary fibrosis (IPF)

Evaluation of exercise tolerance (6-min stepper test (6MST)), quality of life (Visual Simplified Respiratory Questionnaire (VSRQ)) and mood (Hospital Anxiety.

Presentation transcript:

The Epidemiology of Idiopathic Pulmonary Fibrosis Vidya Navaratnam University of Nottingham

What is IPF? Chronic, progressive, fibrotic lung disease of unknown aetiology More common in men Average age of presentation 71 years Median survival 3 years Lots of symptoms 7 years of life lost

How common is IPF?

Textbooks in the 1990s Not a common disease Disease of middle aged people

Number of deaths from CFA in England and Wales

Summary of incidence in early 1990s StudyRate per 100,000 pyrs New Mexico3 UK death certificates2.8 UK general practice4

Incidence over time - update Gribbin Thorax 2006:61:980

Idiopathic Pulmonary Fibrosis -New

Primary Care Data CasesCrude incidence rates (95% CI) per person years Rate Ratios (95%CI) Year (4.95 to 6.74) (5.28 to 7.08)1.08 (0.87 to 1.33 ) (5.83 to 7.68)1.20 (0.98 to 1.48 ) (6.26 to 8.15)1.30 (1.06 to 1.60 ) (7.14 to 9.14)1.41 (1.16 to 1.72 ) (7.21 to 9.19)1.45 (1.19 to 1.77 ) (6.65 to 8.55)1.35 (1.11 to 1.65 ) (8.07 to 10.15)1.63 (1.34 to 1.98 ) (7.12 to 9.08)1.37 (1.12 to 1.67) p for trend <0.0001

Hospital admissions in England

Incidence summary IPF deaths in England and Wales 479 in in 2008 Incidence rate About 8 per 100,000 person years About 5000 new cases a year 5% increase per year

Trent Lung Fibrosis Study: The clot thickens

Thank you Richard Hubbard Andrew Fogarty Norma Thompson Tricia McKeever Gisli Jenkins Sue Ledger Kate Fleming Joe West