INTEL INTERNATIONAL SCIENCE AND ENGINEERING FAIR 2011 Rules and Guidelines

Adult sponsor Oversees project to make sure that student Oversees project to make sure that student is informed of ISEF Rules and Guidelines is informed of ISEF Rules and Guidelines is aware of risks associated with project is aware of risks associated with project is aware of forms required for project is aware of forms required for project will receive proper supervision during experimentation will receive proper supervision during experimentation if required, submits project to IRB or SRC if required, submits project to IRB or SRC Teacher usually serves as Adult Sponsor Teacher usually serves as Adult Sponsor

IRB (Institutional Review Board) Reviews human subject studies Reviews human subject studies Membership must include: Membership must include: an educator an educator a school administrator a school administrator someone knowledgeable about evaluating physical and/or psychological risk: MD, PA, RN, psychiatrist, psychologist, licensed social worker or licensed clinical professional counselor someone knowledgeable about evaluating physical and/or psychological risk: MD, PA, RN, psychiatrist, psychologist, licensed social worker or licensed clinical professional counselor

SRC (Scientific Review Committee ) Reviews some projects before experimentation Reviews some projects before experimentation Reviews all projects just prior to competition Reviews all projects just prior to competition Membership must include: Membership must include: a biomedical scientist (Ph.D., M.D., D.V.M., D.D.S., D.O.) a biomedical scientist (Ph.D., M.D., D.V.M., D.D.S., D.O.) an educator an educator one other member one other member

Forms required for all projects

A Research Plan is required for all projects. It must incorporate all of the relevant topics listed in the Research Plan Instructions.

HUMAN SUBJECTS

What are human subjects studies? Human Subjects studies involve living individuals where there is Intervention or interaction with subjects Intervention or interaction with subjectsand/or Collection of identifiable private information Collection of identifiable private information

Exempt studies – do not require IRB review nor human subjects forms Product testing of a student invention, program, concept, etc. Product testing of a student invention, program, concept, etc. No health hazards No health hazards No personal data collected No personal data collected Feedback directly related to product Feedback directly related to product Studies using pre-existing, publicly available human data Studies using pre-existing, publicly available human data

Additional exempt studies Behavioral observations in unrestricted public settings Behavioral observations in unrestricted public settings No interaction No interaction No manipulation of environment No manipulation of environment No recording of any personal identifiers No recording of any personal identifiers Studies using certified de-identified/ anonymous data Studies using certified de-identified/ anonymous data

Human subjects research The IRB must review and approve the research plan before experimentation begins The IRB must review and approve the research plan before experimentation begins Research subjects 18 years of age or older must give informed consent Research subjects 18 years of age or older must give informed consent Research subjects under 18 must give assent and their parents may be required to give permission Research subjects under 18 must give assent and their parents may be required to give permission Not allowable for JH student in Moore Public Schools

Human subjects research, cont’d The IRB evaluates the project and determines The IRB evaluates the project and determines Risk level Risk level Requirement for Qualified Scientist Requirement for Qualified Scientist Requirement for written informed consent/assent/parental permission Requirement for written informed consent/assent/parental permission Not allowable for JH student in Moore Public Schools

Risk evaluation No more than minimal risk No more than minimal risk Anticipated harm and discomfort not greater than encountered in daily life More than minimal risk More than minimal risk Anticipated harm or discomfort is greater than encountered in daily life More than minimal risk studies should require written consent/assent and parental permission. Final determination for this requirement made by the IRB More than minimal risk studies should require written consent/assent and parental permission. Final determination for this requirement made by the IRB Not allowable for JH student in Moore Public Schools

Types of Risk Physical risks Physical risks Exercise Exercise Ingestion, tasting, smelling, application of substances Ingestion, tasting, smelling, application of substances Exposure to potentially hazardous material Exposure to potentially hazardous material Psychological risks Psychological risks Invasion of privacy Invasion of privacy Subject member of an at-risk group Subject member of an at-risk group Not allowable for JH student in Moore Public Schools

VERTEBRATE ANIMALS

What is a vertebrate animal? Live, nonhuman vertebrate mammalian embryos or fetuses Live, nonhuman vertebrate mammalian embryos or fetuses Bird and reptile eggs within 3 days of hatching Bird and reptile eggs within 3 days of hatching All other nonhuman vertebrates (including fish) at hatching or birth All other nonhuman vertebrates (including fish) at hatching or birth Not allowable for JH student in Moore Public Schools

Prohibited studies Induced toxicity studies involving a poison or toxin that could impair health or destroy life Induced toxicity studies involving a poison or toxin that could impair health or destroy life Behavioral experiments with Behavioral experiments with Conditioning using aversive stimuli Conditioning using aversive stimuli Mother/infant separation Mother/infant separation Induced/learned helplessness Induced/learned helplessness Studies of pain Studies of pain Predator/vertebrate prey experiments Predator/vertebrate prey experiments Not allowable for JH student in Moore Public Schools

Additional restrictions Projects that cause more than momentary pain or suffering or which are designed to kill vertebrate animals are not permitted. Projects that cause more than momentary pain or suffering or which are designed to kill vertebrate animals are not permitted. A weight loss or growth retardation greater than 15% of any experimental or control animal is not permitted A weight loss or growth retardation greater than 15% of any experimental or control animal is not permitted A death rate of 30% or greater in any group or subgroup is not permitted A death rate of 30% or greater in any group or subgroup is not permitted

Behavioral observations of animals are exempt from SRC review if There is no interaction with the animals There is no interaction with the animalsand There is no manipulation of the environment There is no manipulation of the environmentand All federal or state fish, game and wildlife regulations are followed All federal or state fish, game and wildlife regulations are followed

Research sites Examples of non- regulated sites Examples of non- regulated sites Home Home School School Farm, ranch Farm, ranch Zoological parks Zoological parks Field Field Examples of regulated sites ( must have an IACUC review and approval process) Examples of regulated sites ( must have an IACUC review and approval process) Universities Government research agencies Private research laboratories Not allowable for JH student in Moore Public Schools

Requirements for studies at regulated sites Must be approved by IACUC (Institutional Animal Care and Use Committee) Must be approved by IACUC (Institutional Animal Care and Use Committee) Local SRC should review project before experimentation Local SRC should review project before experimentation Experimentation must follow ISEF guidelines Experimentation must follow ISEF guidelines QS completes Form 5B which includes documentation of IACUC approval QS completes Form 5B which includes documentation of IACUC approval Not allowable for JH student in Moore Public Schools

POTENTIALLY HAZARDOUS BIOLOGICAL AGENTS

Potentially hazardous biological agents include Microorganisms (including bacteria, viruses, fungi, etc.) Microorganisms (including bacteria, viruses, fungi, etc.) Recombinant DNA Recombinant DNA Human or animal fresh/frozen tissues, blood or body fluids Human or animal fresh/frozen tissues, blood or body fluids Not allowable for JH student in Moore Public Schools

Studies exempt from prior SRC review and no additional PHBA forms required Studies using baker’s and brewer’s yeast (except rDNA studies) Studies using baker’s and brewer’s yeast (except rDNA studies) Studies using Lactobacillus, B. thurgensis, nitrogen-fixing bacteria, oil-eating bacteria, slime mold and algae-eating bacteria in natural environment. No exempt if cultured in a petri dish environment. Studies using Lactobacillus, B. thurgensis, nitrogen-fixing bacteria, oil-eating bacteria, slime mold and algae-eating bacteria in natural environment. No exempt if cultured in a petri dish environment.

Tissues If animal is euthanized solely for student project – vertebrate animal study which requires IACUC approval If animal is euthanized solely for student project – vertebrate animal study which requires IACUC approval If animal is euthanized for a purpose other than student project – tissue study If animal is euthanized for a purpose other than student project – tissue study Not allowable for JH student in Moore Public Schools

Plant tissues Plant tissues Established cell and tissue cultures Established cell and tissue cultures Meat and meat by-products, pasteurized milk, eggs – from grocery stores, restaurants, packing houses Meat and meat by-products, pasteurized milk, eggs – from grocery stores, restaurants, packing houses Hair Hair Sterilized teeth Sterilized teeth Fossilized tissue/archeological specimens Fossilized tissue/archeological specimens Prepared fixed tissue slides Prepared fixed tissue slides Exempt as PHBA tissues

Form 6B Required for all projects using Required for all projects using Fresh/frozen tissue Fresh/frozen tissue Primary cell cultures Primary cell cultures Blood and blood products Blood and blood products Body fluids Body fluids

HAZARDOUS CHEMICALS, ACTIVITIES OR DEVICES

Hazardous chemicals, activities or devices include Chemicals Chemicals Equipment Equipment DEA-Controlled Substances DEA-Controlled Substances Prescription Drugs Prescription Drugs Alcohol and Tobacco Alcohol and Tobacco Firearms and Explosives Firearms and Explosives Radiation Radiation Not allowable for JH student in Moore Public Schools

General Rules Studies do not require prior SRC review and approval Studies do not require prior SRC review and approval All studies require a Risk Assessment documented on Form 3 All studies require a Risk Assessment documented on Form 3 DEA - controlled substances require a Qualified Scientist DEA - controlled substances require a Qualified Scientist All other studies require a Designated Supervisor All other studies require a Designated Supervisor Not allowable for JH student in Moore Public Schools

DEA-Controlled Substances Consult DEA list of controlled substances Consult DEA list of controlled substances All studies require Qualified Scientist All studies require Qualified Scientist Controlled substances on Schedule 1 require DEA protocol review Controlled substances on Schedule 1 require DEA protocol review Firearms and Explosives Must adhere to local training and certification requirements Must adhere to local training and certification requirements Not allowable for JH student in Moore Public Schools

Must follow local laws for purchase, possession and consumption Must follow local laws for purchase, possession and consumption Home production of ethyl alcohol (wine or beer) must follow U.S. Alcohol and Tobacco Tax and Trade Bureau (TTB) regulations Home production of ethyl alcohol (wine or beer) must follow U.S. Alcohol and Tobacco Tax and Trade Bureau (TTB) regulations Alcohol distillation for fuel production can be conducted at school with TTB permit obtained by school officials Alcohol distillation for fuel production can be conducted at school with TTB permit obtained by school officials Alcohol and Tobacco Not allowable for JH student in Moore Public Schools

Prescription Drugs Cannot be administered to human subjects Cannot be administered to human subjects Animal administration must follow ISEF vertebrate animal guidelines Animal administration must follow ISEF vertebrate animal guidelines Hazardous Chemicals Refer to MSDS Sheets for safety and handling guidelines Refer to MSDS Sheets for safety and handling guidelines Not allowable for JH student in Moore Public Schools

Hazardous Devices Involve level of risk beyond that encountered in student’s everyday life Involve level of risk beyond that encountered in student’s everyday lifeRadiation Non-ionizing Non-ionizing Ionizing Ionizing Not allowable for JH student in Moore Public Schools

Form 3 Required for all projects involving Required for all projects involving DEA-Controlled Substances DEA-Controlled Substances Prescription Drugs Prescription Drugs Alcohol and Tobacco Alcohol and Tobacco Hazardous Chemicals Hazardous Chemicals Hazardous Devices Hazardous Devices Hazardous Activities Hazardous Activities Radiation Radiation

15 Different Categories for Entries Behavioral and Social Sciences* Behavioral and Social Sciences* Biochemistry* Biochemistry* Botany Botany Chemistry Chemistry Computer Science** Computer Science** Earth and Space Sciences Earth and Space Sciences Engineering** Engineering** Environmental Science** Environmental Science** Gerontology* Gerontology* Mathematics** Mathematics** Medicine and Health* Medicine and Health* Microbiology* Microbiology* Physics*** Physics*** Zoology Zoology *Most projects will require prior approval which is not permitted for 6-8 th grade students **Entries are low in these categories ***Most crowded field, consider changes that could move you to less competition.

Prior Approval Projects Students in the 6 th -8 th grade are not permitted to complete a project that requires prior approval, which would include the following: Students in the 6 th -8 th grade are not permitted to complete a project that requires prior approval, which would include the following: Human Subjects (Surveys, physical activities, etc.) Vertebrate Animal Studies Potentially Hazardous Biological Agents Hazardous Chemicals, Activities or Devices If you are unsure as to whether a project would require prior approval or not, please go to and review their rules.

Judging Tips Is your idea creative or something that is entered in every science fair? Is your idea creative or something that is entered in every science fair? Make internet projects your own. Make internet projects your own. Include information that led you to your hypothesis—don’t guess blindly. Include information that led you to your hypothesis—don’t guess blindly. Make your board visually appealing. Make your board visually appealing. Identify your Independent and Dependent variables. Identify your Independent and Dependent variables. Test numerous times. Test numerous times. Do your own work. Do your own work. Use examples from your data to support your conclusion. Use examples from your data to support your conclusion.

Judging Criteria Creative Ability (30 Points Possible) Creative Ability (30 Points Possible) Scientific Thought (30 Points Possible) Scientific Thought (30 Points Possible) Thoroughness (15 Points Possible) Thoroughness (15 Points Possible) Skill (15 Points Possible) Skill (15 Points Possible) Clarity (10 Points Possible) Clarity (10 Points Possible)

Division II Overall Award Winner Danny Chakron,West JH The Dark Side of the Wireless Network