Lein Applied Diagnostics Low Cost Sensing in the Eye.

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Presentation transcript:

Lein Applied Diagnostics Low Cost Sensing in the Eye

Lein Applied Diagnostics The Eye

Lein Applied Diagnostics Eye Diseases and Disorders  Cataract  Glaucoma  Refractive error  Macular degeneration  Diabetes

Lein Applied Diagnostics Current Solutions

Lein Applied Diagnostics Confocal Optical Principle Axial resolution = 1.4 λ n NA 2

Lein Applied Diagnostics Material Intensity Scanning Lens Position Detector

Lein Applied Diagnostics Thickness Measurements Position Signal Amplitude

Lein Applied Diagnostics Thickness Measurements (2) Thickness (microns) Number of measurements  Precision better than 1 micron

Lein Applied Diagnostics Low Cost Design  Innovative, modular optical design  Only 3 optical components  Simple to align

Lein Applied Diagnostics State of the Art

Lein Applied Diagnostics Platform Technology  Confocal scan - highly localised  Scan light through eye  Non invasive, non contact

Lein Applied Diagnostics Ophthalmic Biometry Cornea Lens Anterior Chamber

Lein Applied Diagnostics Auto-RefractionAuto-Refraction

Lens Metrology  Thickness of lenses  Measurement in aqueous solution  Lens power  IOL power

Lein Applied Diagnostics PharmacokineticsPharmacokinetics What the body does to the drug  liberation  absorption  metabolism  distribution  excretion

Lein Applied Diagnostics Other Applications  Thickness of transparent materials  Optical glass using visible light  Silicon using NIR light  Surface profiling  Particle detection

Lein Applied Diagnostics ConclusionsConclusions  Low cost  Accurate, precise  Non-contact  Platform technology