DNA (Deoxyribonucleic Acid) A. DNA 1.Determines traits and codes for proteins 2.Found in nucleus of the cell Pg. 129
DNA (Deoxyribonucleic Acid) B. Structure 1.Shape = Double Helix 2.Subunit= Nucleotide (3 parts) a. Phosphate Group b. Sugar – Deoxyribose c. Nitrogen Base (A,T,C,G) Pg. 129
4 different bases = 4 different nucleotides C G A T
3. Twisted Ladder a. Sides = sugar and phosphate b. Rungs (steps) = bases Pg. 129
Nucleotide (Subunit) Hydrogen Bonds Base Pair Rule A – T G – C
History 1.Rosalind Franklin and Maurice Wilkins – X-ray picture of DNA Pg. 131
Proved DNA had a Helical Shape
2. Watson and Crick – Model of DNA WatsonCrick Pg. 131
3.Chargaff = base pair rule A with T A=adenine T=Thymine G with C G=Guanine C=Cytosine Ex. Strand 1- ATG GGC CTA Strand 2- Pg. 131 TAC CCG GAT
RNA: Ribonucleic Acid A with U A=adenine U=Uracil G with C G=Guanine C=Cytosine DNA: Strand 1- ATG GGC CTA RNA Strand 2- Pg. 131 UAC CCG GAU
DNA Song We love DNA Made of Nucleotides Phosphate, Sugar, and a Base Bonded Down one Side Adenine and Thymine Make a Lovely Pair Cytosine without Guanine Would feel really bare
Pg. 130
DEOXYRIBOSE PHOSPHATE NITROGEN ADENINE GUANINE THYMINE CYTOSINE ADENINE GUANINE CYTOSINE URACIL
FRANKLIN WATSONCRICK RAILS RUNGS DIVIDES INTERPHASE THE SEQUENCE OF BASES
20 UAA UAG UGA AUG RIBOSOME NUCLEUS CYTOPLASM/ RIBOSOME 1
POINT SUBSTITUTION INSERTION DELETION NO 19.What is the name of the chemicals or radiation that can damage DNA and cause mutations ? MUTAGENS 20. What is the central dogma of biology? DNA CODES FOR RNA, WHICH GUIDES THE MAKING OF PROTEINS.