Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Treatment With 9-cis β-Carotene–Rich Powder in Patients With Retinitis Pigmentosa : A Randomized Crossover Trial JAMA Ophthalmol. 2013;131(8): doi: /jamaophthalmol Study DesignStudy design of the 9-cis β-carotene clinical trial. Figure Legend:

Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Treatment With 9-cis β-Carotene–Rich Powder in Patients With Retinitis Pigmentosa : A Randomized Crossover Trial JAMA Ophthalmol. 2013;131(8): doi: /jamaophthalmol Plasma β-Carotene Levels at Each VisitData are presented as means with SEs. a P =.03 for visit 2 vs visit 1 in the Dunaliella-first group. b P <.01 for visit 3 vs visit 4 in the placebo-first group. All other differences were not significant. Figure Legend:

Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Treatment With 9-cis β-Carotene–Rich Powder in Patients With Retinitis Pigmentosa : A Randomized Crossover Trial JAMA Ophthalmol. 2013;131(8): doi: /jamaophthalmol Change in Maximal Dark-Adapted Electroretinographic b-Wave ResponseThe main outcome was the change in maximal dark- adapted electroretinographic b-wave response. The change from baseline to end point in maximal dark-adapted b-wave response was analyzed separately in each eye through paired t test analysis in 29 patients. Data are presented as means and SEs. Figure Legend:

Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Treatment With 9-cis β-Carotene–Rich Powder in Patients With Retinitis Pigmentosa : A Randomized Crossover Trial JAMA Ophthalmol. 2013;131(8): doi: /jamaophthalmol Effect of Dunaliella Treatment on Night VisionRepresentative results of the effect of Dunaliella treatment on night vision of 2 sisters. Arrows mark maximal dark-adapted b-wave. Goldmann kinetic visual fields are shown for large (V3c) and small (II3c) red stimuli (red line) and blue stimuli (blue line). Figure Legend: