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Presentation transcript:

Promoting Maturity Beer Generally speaking Buy or Cell Traffick Jam

This promotes a myeloid progenitor to become a RBC

What is erythropoietin?

This promotes a myeloid progenitor to become a megakaryoblast.

What is thrombopoietin?

This interleukin promotes a myeloid progenitor to become a eosinophil.

What is IL5?

This cytokine is essential for mast cell development.

What is stem cell factor (or c-Kit ligand)?

This TNF family cytokine is required for naïve B cell survival.

What is BAFF (or B cell activating factor)?

It is the “King of Beers”

What is Budweiser?

This brewer claims that its beer is “Good for you”

What is Guinness?

It’s the national beer of Jamaica.

What is Red Stripe?

This is the oldest brewery in America.

What is Yuengling?

When you mind your p’s and q’s, you are minding these.

What are your pints and quarts?

This secondary lymphoid organ is the primary site of imune response to blood borne infections.

What is the spleen?

This cell transports macromolecules from the intestinal lumen into the subepithelial tissue.

What is an M cell?

Along with CD62L, this cell marker is found on naïve T cells and is used to diagnose complete DiGeorge syndrome.

What is CD45RA?

Lymphocyte egress from lymph nodes is dependent on this concentration gradient.

What is S1P/S1P1R?

This interleukin recruits neutrophils, is secreted by macrophages in response to TLR signaling and is a mediator of psoriasis.

What is IL8?

It is the type of cell depicted here.

What is a basophil?

It is the type of cell depicted here.

What is an eosinophil?

It is the type of cell depicted here.

What is a dendritic cell?

It is the type of cell depicted here.

What is a mast cell?

It is the type of cell depicted here.

What is a lymphocyte?

Both of these types of selectins are found on the endothelium.

What are E and P selectins?

L-selectins are highly expressed on naïve T cells mediating their binding to these on HEVs.

What is peripheral node addressin (PNAd)?

MadCAM-1 binds to this integrin on lymphocytes during gut homing.

What is α4β7?

This chemokine receptor is found on naïve T cells and helps them travel to the T cell zone of lymph nodes.

What is CCR7?

This chemokine receptor is found on naïve B cells and helps them travel to lymph node follicles.

What is CXCR5?