Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7 Hyun.

Slides:



Advertisements
Similar presentations
Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.
Advertisements

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.
What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell
Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni
Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet
Human Gut Microbes Use Multiple Transporters to Distinguish Vitamin B12 Analogs and Compete in the Gut Patrick H. Degnan, Natasha A. Barry, Kenny C. Mok,
An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,
Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription Chia-Hsin.
Genes Induced Late in Infection Increase Fitness of Vibrio cholerae after Release into the Environment Stefan Schild, Rita Tamayo, Eric J. Nelson, Firdausi.
The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin- Dependent Autophagy of Intracellular Salmonella Typhimurium Alan Huett, Robert.
Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.
A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.
SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.
Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,
Volume 14, Issue 2, Pages (August 2013)
H. pylori GPS: Modulating Host Metabolites for Location Sensing
Trained Immunity: An Ancient Way of Remembering
P Bodies, Stress Granules, and Viral Life Cycles
Influenza A Virus Lures Autophagic Protein LC3 to Budding Sites
The Avian Influenza Virus Polymerase Brings ANP32A Home to Roost
Influenza Vaccines: Challenges and Solutions
A Way to DAI Cell Host & Microbe
Monocyte-Plasmablast Crosstalk during Dengue
P Bodies, Stress Granules, and Viral Life Cycles
Balance of Power in Host-Virus Arms Races
Jenner's Irony: Cowpox Taps into T Cell Evasion
Niv Zmora, David Zeevi, Tal Korem, Eran Segal, Eran Elinav 
NMD: Nonsense-Mediated Defense
Bacterial Reductionism: Host Thiols Enhance Virulence
Shigella Stays on the Move
Unsweetened IgG Is Bad for Dengue Patients
Portrait of a Killer: Genome of the 2014 EBOV Outbreak Strain
Candida albicans Adds More Weight to Iron Regulation
Shigella Targets T Cells
Octavio Ramilo, Asunción Mejías  Cell Host & Microbe 
In This Issue Cell Volume 158, Issue 5, (August 2014)
Volume 22, Issue 5, Pages (November 2017)
Autophagy, Apoptosis, and the Influenza Virus M2 Protein
A Microbiome Foundation for the Study of Crohn’s Disease
Volume 22, Issue 2, Pages (August 2017)
Type VI Secretion: Not Just for Pathogenesis Anymore
Volume 22, Issue 3, Pages (September 2017)
Merkel Cell Polyomavirus–Positive Merkel Cell Carcinoma Requires Viral Small T- Antigen for Cell Proliferation  Masahiro Shuda, Yuan Chang, Patrick S.
At the Intersection of Plant Growth and Immunity
Monocyte-Plasmablast Crosstalk during Dengue
A Serpin Takes a Bite out of the Flu
The Avian Influenza Virus Polymerase Brings ANP32A Home to Roost
Stress Flips a Chromatin Switch to Wake Up Latent Virus
Finding Leishmania: A Deadly Game of Hide-and-Seek
Breaking the Barrier: Host Cell Invasion by Lujo Virus
HIV Latency Gets a New Histone Mark
Recognizing Macrophage Activation and Host Defense
Gut Microbes Take Their Vitamins
A Microbiome Foundation for the Study of Crohn’s Disease
Inside Job: Viruses Transfer cGAMP between Cells
For HIV, It's Never Too Late to Grow Up
Wilbert Bitter, Coen Kuijl  Cell Host & Microbe 
Viral Suppressors of RNA-Based Viral Immunity: Host Targets
Volume 14, Issue 2, Pages (August 2013)
Plant TRAF Proteins Regulate NLR Immune Receptor Turnover
Antigen Smuggling in Tuberculosis
Viperin Poisons Viral Replication
Two Tales (Tails) of SAMHD1 Destruction by Vpx
Understanding How Hepatitis C Virus Builds Its Unctuous Home
A Host MicroRNA Brokers Truce with HSV-1
Jenner's Irony: Cowpox Taps into T Cell Evasion
HIV and Chemokine Binding to Red Blood Cells—DARC Matters
Don’t Bite the Hand that Feeds You
West African Ebola Virus Strains: Unstable and Ready to Invade?
Time Heals All Wounds … But Wounds Heal Faster with Lactobacillus
Presentation transcript:

Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7 Hyun Jin Kwun, Masahiro Shuda, Huichen Feng, Carlos J. Camacho, Patrick S. Moore, Yuan Chang Cell Host & Microbe Volume 14, Issue 2, Pages (August 2013) DOI: /j.chom Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 1 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 2 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 3 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 4 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 5 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 6 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions

Figure 7 Cell Host & Microbe , DOI: ( /j.chom ) Copyright © 2013 Elsevier Inc. Terms and Conditions Terms and Conditions