Kyung Hee University, Seoul, Korea GI Conference UGI Conference Presented by Byeong-Joo Noh Supervised by Youn-Wha Kim Kyung Hee University, Seoul, Korea.

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Presentation transcript:

Kyung Hee University, Seoul, Korea GI Conference UGI Conference Presented by Byeong-Joo Noh Supervised by Youn-Wha Kim Kyung Hee University, Seoul, Korea

CASE 1 M/ Pleural fluid Pleural fluid Pleura, Biopsy

Kyung Hee University, Seoul, Korea Pleura fluid P Atypical cells, suspicious for carcinoma

Kyung Hee University, Seoul, Korea Pleura fluid P Metastatic adenocarcinoma

Kyung Hee University, Seoul, Korea Pleura, right, biopsy S X100

Kyung Hee University, Seoul, Korea Pleura, right, biopsy S X400

Kyung Hee University, Seoul, Korea CK (+)D2-40, Calretinin, CK5/6 (-)

Kyung Hee University, Seoul, Korea Napsin A (+)TTF-1 (+)

Kyung Hee University, Seoul, Korea Diagnosis Pleura, right, biopsy: Adenocarcinoma, poorly differentiated (History of stomach cancer) > The findings of morphology and immunohistochemical stain, the possibility of lung primary can be considered, rather than stomach primary.

Kyung Hee University, Seoul, Korea CASE 2 M/ Stomach, total gastrectomy Colon, biopsy Perineum, biopsy

Kyung Hee University, Seoul, Korea Stomach, total gastrectomy S

Kyung Hee University, Seoul, Korea Stomach, total gastrectomy S

Kyung Hee University, Seoul, Korea X100 Stomach, total gastrectomy S

Kyung Hee University, Seoul, Korea X200 Stomach, total gastrectomy S

Kyung Hee University, Seoul, Korea X100 Stomach, total gastrectomy S

Kyung Hee University, Seoul, Korea Diagnosis Stomach, total gastrectomy Signet ring cell carcinoma 1) Location: Cardia, Body, Antrum 2) Tumor gross type: Bormann type 4 3) Histologic type by Lauren classification: Diffuse 4) Tumor size: 17.0 cm x 12.0 cm x 1.0 cm 5) Depth of invasion: Tumor invades serosa (pT4a) 6) Margins of resection: No tumor (safety margin: proximal 2.0 cm, distal 2.0 cm) 7) Lymphatic invasion: Present 8) Vascular invasion: Not identified 9) Perineural invaision: Present 10) Regional lymph nodes: Metastasis to 2 of 30 regional lymph nodes (2/30, pN1)

Kyung Hee University, Seoul, Korea X40 Colon, transverse, distal, biopsy S

Kyung Hee University, Seoul, Korea X200 Colon, transverse, distal, biopsy S Signet ring cell carcinoma (History of stomach cancer)

Kyung Hee University, Seoul, Korea X200 Perineum, biopsy S

Kyung Hee University, Seoul, Korea X400 Perineum, biopsy S Metastatic carcinoma

Kyung Hee University, Seoul, Korea CASE 3 M/ Stomach, biopsy (x3) Stomach, wedge resection

Kyung Hee University, Seoul, Korea X40 Stomach, high body, anterior wall, biopsy S

Kyung Hee University, Seoul, Korea X600 Stomach, high body, anterior wall, biopsy S

Kyung Hee University, Seoul, Korea X40 Stomach, high body, lesser curvature, biopsy S

Kyung Hee University, Seoul, Korea X40 Stomach, high body, posterior wall, biopsy S

Kyung Hee University, Seoul, Korea Stomach, high body, AW, wedge resection S

Kyung Hee University, Seoul, Korea Stomach, high body, AW, wedge resection S

Kyung Hee University, Seoul, Korea X12.5 Stomach, high body, AW, wedge resection S

Kyung Hee University, Seoul, Korea X40 Stomach, high body, AW, wedge resection S

Kyung Hee University, Seoul, Korea X40 Stomach, high body, AW, wedge resection S

Kyung Hee University, Seoul, Korea Diagnosis Stomach, high body, anterior wall, wedge resection: Hypertrophic gastropathy

Kyung Hee University, Seoul, Korea CASE 4 M/ Stomach, biopsy (x3) Stomach, distal gastrectomy

Kyung Hee University, Seoul, Korea X40 Stomach, antrum, anterior wall, biopsy S Dysplasia, low grade

Kyung Hee University, Seoul, Korea X40 Stomach, angle, anterior wall, biopsy S Dysplasia, low grade

Kyung Hee University, Seoul, Korea X40 Stomach, low body, posterior wall, biopsy S

Kyung Hee University, Seoul, Korea X100 Stomach, low body, posterior wall, biopsy S Focal carcinoma with high grade dysplasia

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X12.5

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X40

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X40

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X100

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X40

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X200

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S X200

Kyung Hee University, Seoul, Korea Stomach, distal gastrectomy S

Kyung Hee University, Seoul, Korea Diagnosis Stomach, distal gastrectomy: Adenocarcinoma, well differentiated 1) Location: Body, posterior wall 2) Tumor gross type: Early gastric carcinoma, type IIa+IIc 3) Histologic type by Lauren classification: Intestinal 4) Tumor size: 2.5 cm x 1.9 cm x 0.25 cm 5) Depth of invasion: Tumor invades submucosa (sm2) (pT1b) 6) Margins of resection: No tumor (safety margin: proximal 3.3 cm, distal 7.0 cm) 7) Lymphatic invasion: Not identified 8) Vascular invasion: Not identified 9) Regional lymph nodes: No metastasis in 26 regional lymph nodes (0/26, pN0) (perigastric: 0/23, LN#8: 0/3, LN#12: 0/0)

Kyung Hee University, Seoul, Korea Diagnosis 10) Additional pathologic findings: Dysplasia, low to high grade with 1) Size: 7.0 x 2.2 x 0.15 cm (in extent) 2) Negative resection margins (Safety margins: proximal 0.1 cm (very close), distal 4.5 cm)

Kyung Hee University, Seoul, Korea CASE 5 M/ Stomach, biopsy (x2)

Kyung Hee University, Seoul, Korea X40 Stomach, lesser curvature, biopsy S

Kyung Hee University, Seoul, Korea X100 Stomach, lesser curvature, biopsy S Adenocarcinoma, moderately differentiated

Kyung Hee University, Seoul, Korea X100 Esophagus, 27~37 cm from incisor, biopsy S Ulcer with acute and chronic inflammation