Laurence Chan, Ph.D. (Strata America) J. Q. Li (Winner Medical) (Jan. 11, 2008) 1 Properties of Wound Care Products made with Cotton Nonwovens

Scope Traditional Wound Care Products Existing base materials Properties Launching of Cotton Nonwovens Ideal base material Properties Cotton Nonwoven Wound Care Products Characteristics Comparisons with traditional products Conclusions 2

Traditional Wound Care Products 3 Dressing sponges X-ray detectable sponges Laporatomy sponges OR towel IV sponges General purpose sponges Burn dressings

4 Plain Gauze Sponge

5 X-Ray Detectable Sponge

6 Lap Sponge

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8 OR Towel

9 Nonwoven Sponge

10 IV Drain Sponge

Traditional Base Materials Woven Gauze Type VII USP gauze Structure 32’s/19x9 40’s/20x12 Others Non USP gauze 32’s/17x7 Others Synthetic Nonwovens 70/30 Rayon/PET 50/50 Rayon/PET 11

USP Gauze Testing Weight Thread Count Acidity Surface-active substance Starch and dextrin Water-soluble substance Ignite residue Absorption capacity Residue of ignition Fluorescence 12

Other Requirements for Base Materials Appearance Hand (feel) Absorption Capacity Speed (sink time) Debridement and wound treatment Lint and loose thread Tensile properties Foreign particles Bioburden level 13

Applications Woven Gauze Dressing Sponge General purpose sponge Trach sponge X-ray detectable sponge Laporatomy sponge OR Towel IV sponge Synthetic Nonwoven Dressing Sponge General purpose sponge IV sponge 14

15 Physical Data for Gauze and Nonwoven Sponges (A) Gauze Sponge, 4"x4": 32's/19x9 PlyWt., gm Sink Time seconds Absorption gm/sponge Tensile MD, N/5cm Tensile CD, N/5cm (B) Nonwoven Sponge 70Rayon/30PET, 4"x4", 4 Ply: GSMWt., gm Sink Time seconds Absorption gm/sponge Tensile MD, N/5cm Tensile CD, N/5cm

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Woven Gauze Characteristics Favorable Highly Absorbent Good for debridement Autoclavable Predictable properties Large volume of historical data Unfavorable Lint Loose thread Increasingly high cost 18

Synthetic Nonwovens Characteristics Favorable Highly Absorbent Economical No lint No loose thread Unfavorable Not suitable for wound debridement Increasingly high cost of Rayon Not autoclavable 19

Ideal Base Material for Wound Care Products Combining the favorable characteristics of cotton and nonwoven materials: Absorbent Natural cotton feel Good for debridement Autoclavable Economical and stable pricing No lint No loose thread Environmental friendly Low bioburden level and Pyronema free 20

Introducing PurCotton™ Nonwoven Cotton Launched in 2006 by Winner Medical Group. Proprietary and patented spunlace process. Manufactured in ultra modern facility in Huanggang, China Made with USA grown cotton. 21

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Capabilities of PurCotton™ Nonwovens Basis Weight: 30 gsm to 120 gsm Plain or Apertured White or Colored 100% Cotton or Cotton/PET Blend Competitive pricing Comparable to gauze products More affordable than other cotton nonwovens 23

Wound Care Applications for PurCotton™ Plain Dressing Sponge X-ray Detectable Sponge IV Sponge Dental Sponge Laporatomy Sponge OR Towel Others 24

25 PurCotton Dressing Sponge

26 Aperture 1

27 Aperture 2

28 PurCotton X-ray Detectable Sponge

29 PurCotton X-ray Sponge (Sterile)

30 PurCotton Lap Sponge

31 PurCotton OR Towel

32 Cotton Nonwoven: OR Towel and Lap Sponge

33 Typical PurCotton™ Physical Data: 4"x4", 4 Ply Sponge GSM Wt., gm Sink Time, seconds Absorption, gm/sponge Tensile MD, N/5cm Tensile CD, N/5cm

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38 Physical Properties: PurCotton™ vs. Gauze Sponge (A) PurCotton Sponge, 4"x4", 4 Ply GSMWt., gm Sink Time, seconds Absorption, gm/sponge Tensile MD, N/5cm Tensile CD, N/5cm (A) Gauze Sponge, 4"x4": 32's/19x9 PlyWt., gm Sink Time, seconds Absorption, gm/sponge Tensile MD, N/5cm Tensile CD, N/5cm

Physical Properties Summary for PurCotton™ A wide range of properties Basis weight Absorption capacity Tensile properties Aperture White or color 39

Superior Characteristics of PurCotton™ over Gauze Sponge Low Lint and no loose thread Better for wound debridement Very low bioburden level Pyronema free High bleaching temperature and long duration USA grown cotton 40

Nonwoven Cotton/PET Blend Launched in 2007 More economical than PurCotton (100% Cotton nonwoven) Marketing need for an alternative to Rayon/PET blend: Rapidly increasing prices for Rayon More eco-friendly material 41

Nonwoven Cotton/PET Blend Cotton/PET Blend 70/30 50/50 Aperture 24x20 20x10 Typical Basis Weight 30 gsm 40 gsm 50 gsm 42

43 Physical Properties: 70/30 Cotton/PET vs. Rayon/PET (A) Cotton/PET Sponge 70/30, 4"x4", 4 Ply: GSMWt.Sink TimeAbsorptionTensile MDTensile CD (B) Rayon/PET Sponge 70/30, 4"x4", 4 Ply: GSMWt.Sink TimeAbsorptionTensile MDTensile CD

Superior Characteristics of Cotton/PET over Rayon/PET More economical and longer term pricing stability Autoclavable Better hand feel More favorable perception of Cotton by end-users More eco-friendly than Rayon 44

Wound Care Applications for Cotton/PET Blend General Purpose Sponge IV Sponge Dental Sponge Plain Dressing Sponge Others 45

Conclusions Revolutionary spunlace nonwoven for making wound care products: 100% Cotton Nonwovens (PurCotton™) Cotton/PET Blends PurCotton™ 100% Cotton Nonwoven Ideal material combining best characteristics of cotton and nonwoven Wide range of properties for making various wound care products Nonwoven Cotton/PET Blend Longer term pricing stability over Rayon/PET Superior properties and more eco-friendly 46