Figure S9. 65 genes classifying early and late acute and convalescent phases on HG-focus platform* Gene symbolGene title p value (Phases) Fold change (early.

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Figure S9. 65 genes classifying early and late acute and convalescent phases on HG-focus platform* Gene symbolGene title p value (Phases) Fold change (early acute vs convalescent) Fold change (late acute vs convalescent) BIRC5baculoviral IAP repeat-containing 53.19E BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)7.16E CACNA2D3calcium channel, voltage-dependent, alpha 2/delta subunit 33.39E CCL2chemokine (C-C motif) ligand 24.08E CCL8chemokine (C-C motif) ligand 88.67E CCNA2cyclin A28.60E CCNB2cyclin B21.98E CD1CCD1c molecule8.18E CD38CD38 molecule4.12E CDC20cell division cycle 20 homolog (S. cerevisiae)5.06E CDK1cyclin-dependent kinase 12.29E CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)7.95E CDKN3cyclin-dependent kinase inhibitor 32.74E CKS2CDC28 protein kinase regulatory subunit 21.88E CTSL1cathepsin L15.25E CXCL10chemokine (C-X-C motif) ligand E EEF1B2eukaryotic translation elongation factor 1 beta 21.13E FABP5fatty acid binding protein 5 (psoriasis-associated)7.13E FEN1flap structure-specific endonuclease 16.66E GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)2.34E GINS2GINS complex subunit 2 (Psf2 homolog)8.24E GMNNgeminin, DNA replication inhibitor2.56E HERC5hect domain and RLD 51.80E HESX1HESX homeobox 13.60E HMMRhyaluronan-mediated motility receptor (RHAMM)1.26E IFI27interferon, alpha-inducible protein IFI44interferon-induced protein E IFI44Linterferon-induced protein 44-like1.22E IFIH1interferon induced with helicase C domain 12.80E IFIT1interferon-induced protein with tetratricopeptide repeats 15.94E IFIT3interferon-induced protein with tetratricopeptide repeats 32.66E IFITM3interferon induced transmembrane protein 3 (1-8U)8.60E IRF7interferon regulatory factor 77.95E ISG15ISG15 ubiquitin-like modifier1.16E LAMP3lysosomal-associated membrane protein 31.42E LGALS3BPlectin, galactoside-binding, soluble, 3 binding protein2.35E MCM6minichromosome maintenance complex component 69.54E MS4A4Amembrane-spanning 4-domains, subfamily A, member 47.39E MT2Ametallothionein 2A7.98E MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)4.57E MX2myxovirus (influenza virus) resistance 2 (mouse)4.61E NCAPGnon-SMC condensin I complex, subunit G4.45E NELL2NEL-like 2 (chicken)2.32E NME1non-metastatic cells 1, protein (NM23A) expressed in5.15E NUSAP1nucleolar and spindle associated protein 17.81E OAS12',5'-oligoadenylate synthetase 1, 40/46kDa1.06E OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa7.74E OAS32'-5'-oligoadenylate synthetase 3, 100kDa2.27E OASL2'-5'-oligoadenylate synthetase-like1.65E PBKPDZ binding kinase4.42E PCNAproliferating cell nuclear antigen2.53E PLSCR1phospholipid scramblase 18.26E PTTG1pituitary tumor-transforming 12.87E RRM2ribonucleotide reductase M21.40E

Figure S9 Continued RTN1reticulon 16.90E SERPING1serpin peptidase inhibitor, clade G (C1 inhibitor), member 13.33E SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin5.05E STMN1stathmin 17.30E TNFSF10tumor necrosis factor (ligand) superfamily, member E TOP2Atopoisomerase (DNA) II alpha 170kDa8.00E TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)1.75E TYMSthymidylate synthetase UBE2Cubiquitin-conjugating enzyme E2C6.11E USP18ubiquitin specific peptidase E ZWINTZW10 interactor2.65E *Symbols in red are phase classifiers found on both the HG-focus and HG-U133plus2 platforms.