Orthopaedic Oncology Radiology Review Tae Won Kim, MD PCOM Tumor Review
Goals X-ray Bone Scan CT Scan MRI PET Scan
Staging Studies 10 yo male presents with following x-ray. Measures 10cm cranio- caudal. Biopsy reveals osteosarcoma. What is the patients AJCC and MSTS stage if: 1.+Lung nodules 2.No lung nodules
Describe the xray
Enneking 4 Questions Where is the lesion? Central: lies on exact central axis of bone Eccentric: one side of central axis yet within cortices Cortical: center of lesion within substance of cortex Parosteal: center of lesion in soft tissue external to bone Joint: center of lesion within joint
What is the lesion doing to the bone? Type of destruction: types I-III I.Geographic: single large hole, punched out between intact and destroyed II.Moth-eaten: irregular poorly define margin III.Permeative: numerous elongated slotted holes parallel to long axis
What is the bone doing to the lesion? – Periosteal reaction – “Codman’s triangle” – “Onion skinning” – “Buttressing”
Are there any clues (ie. Matrix) on the x-ray that could provide information about the lesion? -Lytic -Blastic -Ground glass -Flocculent, popcorn, punctate -Cloud or smoke-like -Fat -Solid
Bone Scan
Active Material Technetium-99-MDP methylene diphosphonate
Interpret Bone Scan
CT Scan
MRI T1 vs T2 Fat suppressed Pre vs post-contrast
Why do we use contrast? Bright post contrast = vascular Dark post contrast = avascular
Basics Dark T1, Dark T2
Bright T1, Dark T2, Dark fat suppressed Lipoma
Dark T1, Bright T2, No enhancement post- contrast T2 Cysts
Dark T1, Bright T2, Enhance post-contrast T2 SARCOMA!
Dark T1, Bright T2, Rim-enhancing T2 Abscess/Cyst or Sarcoma
MRI Well Circumscribed Soft Tissue masses – think Malignancy Ill-define Soft tissue masses – think Benign
PET Scan
PET-CT Scan
FDG (Fluorodeoxyglucose)
Images
50 y/o with Foot Pain
Giant Cell Tumor of Bone
Osteosarcoma