1 Chapter 25 Lecture Outline

2 1. ntroduction

3 2. Structure and Bonding

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6 3. Nomenclature Secondary and tertiary amines having identical alkyl groups are named using the prefix di- or tri- with the name of the primary amine.

7 Secondary and 3 ° amines having more than one kind of alkyl group are named as N-substituted primary amines using the following procedure:

8 Aromatic amines are named as derivatives of aniline. There are many different nitrogen heterocycles, each with a different name. The N atom is considered to be at position “1”.

9 4. Physical Properties

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11 5. Preparation

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13 Gabriel Synthesis of 1 ° Amines

14 Reduction of N-Containing Functional Groups

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16 Reductive Amination

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18 Retrosynthetic Direction

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20 6. Reactions of Amines

21 Amines as Bases

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28 7. Amines Nucleophiles

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30 Hofmann Elimination

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34 Reaction of Amines with Nitrous Acid

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36 2° Alkylamines and aryl amines react with nitrous acid to form N-nitrosamines.

37 Substitution Reactions of Aryl Diazonium Salts

38 Sandmeyer reaction.

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44 Coupling Reactions of Aryl Diazonium Salts

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46 Pop Quiz 25 장 [A] 1 차 아민을 모두 고르세요 [B] 2 차 아민을 모두 고르세요