Report of the SIG HBOT and Neurorehabilitation Chair Meeting, Abu Dhabi 5 th -8 th March, 2015 Chair: F.Gerstenbrand, Vienna Co-Chair: T.Sieber, Piestany.

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Presentation transcript:

Report of the SIG HBOT and Neurorehabilitation Chair Meeting, Abu Dhabi 5 th -8 th March, 2015 Chair: F.Gerstenbrand, Vienna Co-Chair: T.Sieber, Piestany

Main Aims of the SIG HBOT and Neurorehabilitation Application of HBOT method in the rehabilitation of TBI, stroke, paediatric neurology, vegetative state/apallic syndrome. Clinical trials in cooperation with competent SIG’s Working basis: HBO Department of Adeli Medical Center, Piestany, Slovakia.

Oxymed Department, HBOT Chamber Adeli Medical Center, Piestany, Slovakia

Special Treatment Program Adeli Center Piestany for Cerebral Palsy

History of Hyperbaric Oxygenation Chamber Oxymed Department Adeli Center Piestany “ The Domicilium” from 1662 Fontaine’s mobile hyperbaric operating room Cunningham's hyperbaric chamber In Cleveland seat hyperbaric chamber HAUX STARMED 2200 / 5.5 / XL – 2014 Oxymed Center, Piestany

Hyperbaric Oxygenation Therapy use of 100% Oxygen higher than atmospheric pressure

Under HBOT O 2 Increased in: Bone Urine Plasma Lymph And Most Importantly the Cerebrospinal Fluid

Under pressure free molecular oxygen is delivered directly to the cell for immediate metabolic use without energy exchange. Edward Teller

Effects of Pressurized Oxygen Chronic Brain Damage Restores the integrity of the blood brain barrier and cell membranes Improves cell respiration, Reduces cell byproducts – cytokines Promotes Neovascularization Promotes Epithelization

Effects of Pressurized Oxygen Chronic Brain Damage Reactivates idling neurons Enhances plasticity Efficiently elevates diffusional driving force for O 2 thereby increasing tissue oxygen availability Promotes phagocytosis (internal debridement) Ameliorates multiple biochemical changes

HBOT and hypoxic damage of the brain Early form of HBOT (within 24 hours) Deferred form of HBOT (months to years Treatment structure: 1,2 - 1,5 bar 75-90min 10-40x

Hyperbaric Oxygen Therapy Complex effect Stimulates DNA in each cell Promotes growth of new tissue Affects perfusion (NO) Produces oxygen free radicals Inhibits acute inflammation Attenuates the apoptosis of cells Reactivates “sleeping” (idling) neurons

Results – Cochrane review Traumatic Brain Injury – Artru (1976), Holbach (1974), Rockswold (1992), Ren (2001) Neonatal hypoxic encephalopathy – Hutchinson (1966), Liu (2006) Cerebral Palsy – Machado (1989), Montgomery (1999), Packard (2000), Collet (2001), Mathai (2005)

Presentation of patients treated in the Adeli Medical Center Piestany

Possibilities of cooperation with other SIG‘s - Paediatric neurorehabilitation -Early rehabilitation -Severe brain injury -Spinal cord injury -Neurological rehabilitation -Autonomic rehabilitation -Neurosurgical, reconstructive and restaurative rehabilitation