FP7 UK Technology Strategy Board Driving Innovation Horizon 2020 – The Health Challenge Manchester – 12 th November 2013 Octavio Pernas - FP7UK National Contact Point for Health

FP7 UK Technology Strategy Board Driving Innovation Facts and figures Policy overview What’s on the Horizon 2020 The Health Challenge Agenda

FP7 UK Technology Strategy Board Driving Innovation Facts and figures Policy overview What’s on the Horizon 2020 The Health Challenge Agenda

FP7 UK Technology Strategy Board Driving Innovation Year Total Funding Projects Funded Topics SME Targeted 2007€641 million153870% 2008€577 million172870% 2009€593million108710% 2010€628 million131720% 2011€657 million % 2012€657 million % 2013€819 million % Facts and figures FP7 Health Theme Funding,

FP7 UK Technology Strategy Board Driving Innovation FP7-HEALTH-2013-Innovation-1 (35 topics, €679 million) Opening: 10 Jul stage 1 proposals, deadline: 3 Oct – 1281 proposals evaluated evaluation: => 370 proposals invited to submit full proposal (6 Dec.) stage 2 proposals, deadline: 6 Feb => 364 proposals submitted 128 proposals short-listed for funding (18 Apr.) Validation and negotiation! Facts and figures FP Health Call

FP7 UK Technology Strategy Board Driving Innovation UK has highest level of participation in successful health projects Facts and figures FP7 Health Theme – Participants

FP7 UK Technology Strategy Board Driving Innovation UK organisations have secured > €670 million of EU funding for Health research Facts and figures FP7 Health Theme – EC contribution (€ M)

FP7 UK Technology Strategy Board Driving Innovation Facts and figures Policy overview What’s on the Horizon 2020 The Health Challenge Agenda

FP7 UK Technology Strategy Board Driving Innovation Policy context Historical milestones in the European Union European Research Policy - Development and evolution of European Research and Technological Framework Programmes Lisbon Strategy / European Research Area (ERA) Europe 2020 / 7 Flagships Initiatives / Innovation Union Multiannual Financial Framework (MFF, ) Adoption process of Horizon 2020 Policy overview

FP7 UK Technology Strategy Board Driving Innovation What is Horizon 2020? Financial instrument implementing the Innovation Union (Europe 2020 flagship initiative) Policy context Policy overview

FP7 UK Technology Strategy Board Driving Innovation Facts and figures Policy overview What’s on the Horizon 2020 The Health Challenge Agenda

FP7 UK Technology Strategy Board Driving Innovation Horizon 2020: What is it? billion euro research and innovation funding programme ( ) New framework programme bringing together three separate programmes/initiatives (FP, EIT, CIP) Continuation of investment in frontier research More support for innovation activities – focus on business opportunities Simplification (e.g. reduction of average time to grant by 100 days) What’s on the Horizon 2020

FP7 UK Technology Strategy Board Driving Innovation Single set of rules for participation, coherent with other new EU Programmes One project – one funding rate - Eligible costs: direct + indirect (flat rate, 25% of direct costs) - 100% rate for research projects; - 70 % rate for activities closer to market; Simple evaluation criteria: Excellence, Impact, Implementation New funding schemes: pre-commercial procurement, prizes, loan and equity instruments, etc. Horizon 2020: What’s new? What’s on the Horizon 2020

FP7 UK Technology Strategy Board Driving Innovation 1.Excellent Science 2.Competitive Industries 3.Better Society Horizon 2020: Three priorities What’s on the Horizon 2020

FP7 UK Technology Strategy Board Driving Innovation European Research Council (ERC) Supporting world leading scientist in blue sky research Future and Emerging Technologies (FET) Collaborative research to open new fields of innovation 2.46 Marie Skłodowska-Curie actions (MSCA) Opportunities for training and career development 5.62 Research infrastructures (including e-infrastructure) Ensuring access to world-class facilities 2.27 Horizon 2020: Excellent Science (€Bn) What’s on the Horizon 2020

FP7 UK Technology Strategy Board Driving Innovation Leadership in enabling and industrial technologies (LEIT) ICT (45 %), nanotechnologies (22 %), biotechnology (3 %), etc Access to risk finance Leveraging private finance and venture capital for research and innovation 2.59 Innovation in SMEs Fostering all forms of innovation in all types of SMEs 0.6 complemented by c. 20% of societal challenges and industrial leadership and ‘access to risk finance’ with strong SME focus Horizon 2020: Competitive Industries (€Bn) What’s on the Horizon 2020

FP7 UK Technology Strategy Board Driving Innovation IDEAcontinued support throughout the projectMARKET Concept & Feasibility Assessment Demonstration Market Replication R&D Commercialisation Idea to concept, risk assessment, technological & commercial feasibility Demonstration, prototyping, testing, market replication, scaling up, miniaturisation, research Quality label for successful projects, access to risk finance, indirect support SME window EU financial facilities Horizon 2020: SME instrument

FP7 UK Technology Strategy Board Driving Innovation Health, demographic change and wellbeing6.81 Food security, sustainable agriculture & the bioeconomy3.51 Secure, clean and efficient energy5.40 Smart, green and integrated transport5.78 Climate action, resource efficiency and raw materials2.81 Europe in a changing world - inclusive, innovative and reflective societies 1.20 Secure societies – protecting freedom and security of Europe and its citizen 1.50 Horizon 2020: Better Society (€Bn) What’s on the Horizon 2020

FP7 UK Technology Strategy Board Driving Innovation JRC 3 Pillar Structure Industrial Leadership Innovation in SMEs Access to Risk Finance Leadership in Enabling and Industrial Technologies Excellent Science European Research Council (ERC) Marie Skłodowska- Curie actions Research Infrastructures Future & Emerging Technologies (FET) Societal Challenges Health, demographic change and wellbeing Food security, sustainable agriculture, forestry, marine, maritime, inland water and bio- economy Secure, clean and efficient energy Smart, green and integrated transport Climate action, environment, resource efficiency and raw materials Secure societies – protecting freedom and security of Europe and its citizens Inclusive, innovative and reflective societies EIT Spreading Excellence and Widening Participation Science with and for Society

FP7 UK Technology Strategy Board Driving Innovation Facts and figures Policy overview What’s on the Horizon 2020 The Health Challenge Agenda

FP7 UK Technology Strategy Board Driving Innovation Health, demographic change and wellbeing challenge (SC1) Less prescription – what to do, but not how to do it Strengthening competitiveness of EU industries - development of new market opportunities Multidisciplinary approach - fostering cooperation between academic and industrial sectors Also implemented by the Innovative Medicines Initiative (IMI) 2; European & Developing Countries Clinical Trials Partnership (EDCTP); Ambient Assisted Living (AAL) 2 The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation SC1 – Draft work programme Work programmes with a 2 year-duration! 15 topics in the ‘co-ordination activities’ call (7 ERA-NET) 36 topics in the ‘personalising health and care’ focus area call Objectives: Create opportunities for real breakthrough research Translation of findings into the clinic Reduce health inequalities Promote active and healthy ageing The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation SC1 – ‘Personalising health and care’ 1.Understanding health, ageing and disease – 3 topics 2.Effective health promotion, disease prevention, preparedness and screening – 6 topics 3.Improving diagnosis – 3 topics 4.Innovative treatments and technologies – 6 topics 5.Advancing active and healthy ageing – 4 topics 6.Integrated, sustainable, citizen-centred care – 8 topics 7.Improving health information, data exploitation and providing an evidence base for health policies and regulation – 6 topics The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation PHC ) Development of new diagnostic tools and technologies: in vitro devices, assays and platforms Specific challenge: The development of new diagnostics (more sensitive, robust and selective) for improved clinical practice demands the translation of multidisciplinary scientific and technological knowledge from diverse fields into clinical applications. (…) A wide range of multidisciplinary competencies need to be brought together to develop and bring new diagnostics to the patient. This is also a field where many small European companies are active. Scope: Proposals will focus on the development of innovative in vitro diagnostic tools and technologies (not novel applications of existing ones) (…) Expected impact: New in vitro diagnostic tools and methods providing more accurate, more reliable and earlier disease diagnosis (…) Type of action: Research and Innovation action SC1 – Understanding the needs The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation Work Programme Call Fiche Annexes Guide for Applicants Financial guide Participant portal The Health Challenge Read all relevant documents!

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Understanding health, ageing and disease PHC Understanding health, ageing and disease: determinants, risk factors and pathways 4 – 6R&I Action PHC2-2015Understanding diseases: systems medicine4 – 6R&I Action PHC Understanding common mechanisms of diseases and their relevance in co- morbidities 4 – 6R&I Action SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Effective health promotion, disease prevention, preparedness and screening PHC Health promotion and disease prevention: improved inter- sector co-operation for environment and health based interventions 4 – 6R&I Action PHC5-2014Health promotion and disease prevention: translating ‘omics’ into stratified approaches 4 – 6 R&I Action PHC Evaluating existing screening and prevention Programmes 2 – 3 R&I Action PHC Improving the control of infectious epidemics and foodborne outbreaks through rapid identification of pathogens (see also SC2) 15 – 20 R&I Action PHC8-2014Vaccine development for poverty-related and neglected infectious diseases: Tuberculosis 15 – 20R&I Action PHC9-2015Vaccine development for poverty-related and neglected infectious diseases – HIV/AIDS 15 – 20R&I Action SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Improving diagnosis PHC Development of new diagnostic tools and technologies: in vitro devices, assays and platforms 4 – 6R&I Action PHC Development of new diagnostic tools and technologies: in vivo medical imaging technologies 4 – 6 R&I Action PHC and 2015Clinical validation of biomarkers 2 – 5SME instrument SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Innovative treatments and technologies PHC New therapies for chronic non-communicable diseases4 – 6R&I Action PHC New therapies for rare diseases 4 – 6R&I Action PHC and 2015Clinical research on regenerative medicine 4 – 6R&I Action PHC Tools and technologies for advanced therapies 4 – 6R&I Action PHC Comparing the effectiveness of existing healthcare interventions in the elderly 4 – 6R&I Action PHC Establishing effectiveness of health care interventions in the paediatric population 4 – 6R&I Action SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Advancing active and healthy ageing PHC Advancing active and healthy ageing with ICT: Service robotics within assisted living environments 3 – 4R&I Action PHC Advancing active and healthy ageing with ICT: ICT solutions for independent living with cognitive impairment 2 – 3Inn Action PHC Advancing active and healthy ageing with ICT: Early risk detection and intervention 3 – 4R&I Action PHC Promoting mental wellbeing: in the ageing population 4 – 6R&I Action SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Integrated, sustainable, citizen-centred care (I) PHC Developing and comparing new models for safe and efficient, prevention oriented, health and care systems 4 – 6R&I Action PHC Piloting personalised medicine in health and care systems 12 – 15R&I Action PHC Advanced ICT systems and services for Integrated Care 3 – 5R&I Action PHC Self-management of health and disease: citizen engagement and mHealth 3 – 5R&I Action SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Integrated, sustainable, citizen-centred care (II) PHC Self-management of health and disease and patient empowerment supported by ICT 3 – 5 Pre- commercial procurement PHC Self-management of health and disease and decision support systems based on predictive computer modelling used by the patient him or herself 3 – 5R&I Action PHC Public procurement of innovative eHealth services 4 – 5 Public procurement of innovative solutions PHC eHealth Sectoral Inducement Prize2 Inducement prize SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Improving health information, data exploitation and providing an evidence base for health policies and regulation PHC Digital representation of health data to improve disease diagnosis and treatment 3 – 5R&I Action PHC Foresight for health policy development and regulation 2 – 3R&I Action PHC Advancing bioinformatics to meet biomedical and clinical needs 2 – 3R&I Action PHC New approaches to improve predictive human safety testing 10 – 15R&I Action PHC eHealth interoperability1CSA PHC Inducement prize – topic TBCTBC Inducement prize SC1 – ‘Personalising health and care’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Co-ordination activities (I) HC Innovation Partnership: Support for the European Innovation Partnership on Active and Healthy Ageing 1 – 2CSA HC Joint Programming: Coordination Action for the Joint Programming Initiative (JPI) "More Years, Better Lives - the Challenges and Opportunities of Demographic Change" 1 – 2CSA HC Support for the European Reference Networks: Efficient network modelling and validation 0.5CSA HC Support for international infectious disease preparedness research 2 – 3CSA SC1 – ‘Coordination activities’ The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation AREA CODETITLE BUDGET (€M) TYPE OF ACTION Coordination activities (II) HC Global Alliance for Chronic Diseases: prevention and treatment of type 2 diabetes 1 – 3R&I Action HC Global Alliance for Chronic Diseases: subject to be confirmed 1 – 3R&I Action HC New approaches to bridge the divide in European health research and innovation 1CSA HC Mobilisation and mutual learning action plan in the area of societal challenge 1 1CSA SC1 – ‘Coordination activities’ The Health Challenge Plus 7 ERA-Net topics (funding bodies, coordination of agendas)

FP7 UK Technology Strategy Board Driving Innovation Next steps Draft Work Programme under discussion Health Information Day: 22 nd November 2013, Brussels * Publication of the call for proposals: 11 th December 2013 (indicative date) * The Health Challenge

FP7 UK Technology Strategy Board Driving Innovation European Commission – Horizon 2020: Participant portal: Fit for Health: Healthcompetence: _Connect (NCP network): Further information

FP7 UK Technology Strategy Board Driving Innovation Website: E mail: Phone: Mobile: Alternative: Alex Harris FP7 Health National Contact Point: Octavio Pernas