JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” The Joint Programming Initiative on “Neurodegeneration”. Dr. Rafael De Andrés-Medina Spain. Berlin, March 19 th & 20 th, 2012 General Assembly

JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” JUMPAHEAD is a CSA for the JP ND preparatory work in 3 years time (2 M € / 6 countries, other participating countries at their own cost). WWPP: Coordination, Mapping of Existing Activities; Drafting the Strategic Research Agenda (SRA); to Prepare SRA Implementation (funding instruments); Diffusion and Communicat;Monitoring.. SRA -Strategiec Research Agenda.Made Public: 7 Februry 2012 In particular. Implementation initiatives Pilot call : (on validation of biomarkers), ERA-Net model, virtual common pot: 13 M € for 4 awarded 3 year projects COEN – Centre of Excellence Network initiative: 6 countries, 7 M € Implementation initiative(s) (to be drafted) SUMMARY

JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” Research on genetic susceptibility and genome-wide association studies (GWAS). Developing animal models. Basic research on pathophysiology. Development of new imaging technologies and new biomarkers. Studying early onset forms of Alzheimer’s disease and related dementia. Development of new treatment strategies. Coordinate biobanks for blood samples, cerebro-spinal fluid (CSF), brain tissues. Launching or integrating large population cohorts or registries. Early diagnosis using a multidisciplinary approach. Prevention to reduce the burden of dementias. Investigator-driven clinical trials. Standardisation of diagnostic criteria and diagnostic instruments. Comparison of different systems and identification of best practice. Home automation, smart homes and domotics. Ethics and health economics. Basic Medical Health & Social Services

Country Management Board, Organisations Albania  UHC "Mother Tereza" Belgium  Department of Economy, Science and Innovation - EWI, Flanders Government  Service Public de Wallonie Czech Republic  Centre of Gerontology of Prague 8 district Authority. Cooperation centre of the Charles University in Prague Faculty of Humanities  Charles University and Motol Hospital Denmark  Danish Council for Strategic Research  Ministry of Science, Innovation and Higher Education Finland  Academy of Finland France  French Foundation of Scientific cooperation in Alzheimer  Multi-Body Subject-Specific Institutes "Neurosciences, Cognitive Sciences,Neurology, Psychiatry"  ANR – National Agency of Research Germany  DLR Greece  Department of European Affairs Ministry of Education, Life Long Learning and Religious Affairs Hungary  National Innovation Office Ireland  Health Research Board  Science Foundation Ireland Italy  Center of excellence on Neuro. Deg Diseases. University of Milan  MUIR – Ministry of Universities, Education and Research Luxembourg  Fonds National de la Recherche Netherlands  ZonMw  Ministry of health, Welfare and Sport Norway  The Research Council of Norway  Norwegian Ministry of Health and Care services Poland  Medical Research center of the Polish Academy of Sciences,  Ministry of Science and Higher Education Portugal  FCT - Foundation for the Science and Technology Slovenia  Neurological clinic - University Medical Center in Ljubljana  Minister of Higher Education, Science and Technology Slovak Republic  Institute of Neuroimunology, Slovak Academy of SciencesInstitute of Neuroimunology, Slovak Academy of Sciences  Ministry of Education of the Slovak Republic Spain  ISCIII- National Institte of Health Carlos III  CDTI- Center for the Technology Industirsl Development Sweden  Swedish Council for Working Life and Social Research  Sweden Research Council Switzerland  Swiss National Science Foundation UK  MRC Turkey  Tübitak

JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” Implementation initiative(s) 2012 e.g. call-2 and/or other ones to be drafted expected to be launched at the end of 2012 Initial funding commitment unknown yet JUMPAHEAD is a CSA for the JP ND preparatory work in 3 years time (2 M € / 6 countries, other participating countries at their own cost). WWPP: Coordination, Mapping of Existing Activities; Drafting the Strategic Research Agenda (SRA); to Prepare SRA Implementation (funding instruments); Diffusion and Communication;Monitoring. 2011: Pilot call (on validation of biomarkers). ERA-Net model, virtual common pot: 13 M € for 4 awarded 3 year projects COEN – Centre of Excellence Network initiative: countries, 7 M € SRA - Strategiec Research Agenda - Made Public: February 7th, 2012

JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” Supporting documents Terms of Reference (ToR). SRA. Survey summary. (scientific priorities and enabling activities). Instruments (other than calls). Template (WG report). Implementation initiative(s) From Development to Implementation, Process - I

JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” Scientific and societal impact.. Instrument(s). Time and budget scale. Added value to already existing initiatives. possible involvement of industry.. Possible involvement of already existing initiatives.. Prioritization.. WG 1. Population-based, patient cohorts and longitudinal studies. WG 2. Uncover new genetic, epigenetic and environmental risk factors. WG 3. Developing therapies, preventive strategies and interventions. WG 4. Health care and social care. Working Groups Implementation initiative(s) From Development to Implementation, Process - II

Implementation Working Group 1 Working Group 2 Working Group 3 Working Group 4 SC MB Task Force Task Force Task Force Implementation initiative(s) From Development to Implementation, Process Outcome:2 - 3 large scale initiatives. 2 or more small initiatives. for the next years.

JPI “More Years, Better Lives: The Potential and Challenges of Demographic Change” 9 ¡ THANK YOU !