Meg Watson, MPH Recent Trends in HPV-Associated Cancers among Women Epidemiology and Applied Research Branch Division of Cancer Prevention and Control.

Slides:



Advertisements
Similar presentations
Correspondence between interracial births and multiple race reporting in the National Health Interview Survey Jennifer D. Parker Academy Health Annual.
Advertisements

HPV-RELATED CANCER Understanding the Burden of HPV Disease and the Importance of the HPV Vaccine Recommendation Lois Ramondetta, MD Professor Gynecologic.
Ralph S. Caraballo, PhD, MPH Valerie J. Rock, MPH Epidemiology Branch Chief Office on Smoking and Health CDC TM 2nd Conference on Menthol Cigarettes October.
Speaker: Decca Mohammed, MD.  Statistics for cervical cancer and HPV  Association of HPV to cervical cancer, and other cancers  Prevention  Screening.
STDs and HIV Among Youth in Nevada
Asthma Prevalence in the United States National Center for Environmental Health Division of Environmental Hazards and Health Effects June 2014.
Gayle Greer Clutter, R.T., CTR Program Consultant
CPCRN Meeting Linda Mulvihill Cancer Surveillance Branch Division of Cancer Prevention and Control October 2009 Department of Health and Human Services.
Routine HIV Screening in Health Care Settings David Spach, MD Clinical Director Northwest AIDS Education and Training Center Professor of Medicine, Division.
Disparities in Cancer September 22, Introduction Despite notable advances in cancer prevention, screening, and treatment, a disproportionate number.
Epidemiology of Oral Cancer Module 1:. Epidemiology of Cancer, U.S.
Cervical Cancer in California Janet Bates, MD MPH Research Program Director Research and Surveillance Program California Cancer Registry.
HIV-Infected Women: An Update June 28, 2007 Kathleen McDavid, PhD, MPH HIV Incidence and Case Surveillance Branch Division of HIV/AIDS Prevention, CDC.
Assessing Minority Participation in Clinical Trials: Setting Attainable Goals The Minority and Women Clinical Trials Recruitment Program Department of.
Epidemiology of a Chronic Disease Exercise By Mary Murphy April 2008
The National Program of Cancer Registries: Enhancing Cancer Incidence Data … Hannah K. Weir, PhD Division of Cancer Prevention and Control Centers for.
Minnesota Department of Health
INCIDENCE AND SURVIVAL TRENDS OF COLORECTAL CANCER FROM 2002 TO 2011 BE Ansa; E Alema-Mensah; MD Claridy; JQ Sheats; B Fontenot, and SA Smith Georgia Regents.
Poverty and HIV Infection: NHBS National* and San Diego Findings Vanessa Miguelino-Keasling, MPH National HIV Behavioral Surveillance System.
Midcourse Assessment of Healthy People 2010 Goal II Suzanne P. Hallquist, MSPH Kenneth G. Keppel, PhD National Center for Health Statistics Centers for.
All Slides Sexually Transmitted Disease Surveillance 1998 Division of STD Prevention.
HIV/AIDS among Women in Texas Enhanced Perinatal Surveillance May 30, 2007 Nita Ngo, MPH.
National Program of Cancer Registries
CANCER INCIDENCE IN NEW JERSEY BY COUNTY, for the Comprehensive Cancer Control Plan County Needs Assessments August 2003 Prepared by: Cancer.
ABSTRACT Background: In late 2003, a group of Centers for Disease Control and Prevention/National Program of Cancer Registries (CDC/NPCR) staff and faculty/staff.
Alaska Native Tumor Registry Alaska Native Epidemiology Center 40-Year Trends in Cancer Incidence among Alaska Native People
Update EPIDEMIOLOGY AND APPLIED RESEARCH BRANCH Division of Cancer Prevention and Control Mary C. White, Sc.D. National Comprehensive Cancer Control Program.
Kevin Fenton, MD, PhD National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention August 5, 2008 Update on the US HIV/AIDS Crisis: Current Trends,
CLINICAL PREVENTIVE SERVICES Chartbook on Healthy Living.
Gateway to the Future: Improving the National Vital Statistics System St. Louis, MO June 6 th – June 10 th, 2010 Is There Progress Toward Eliminating Racial/Ethnic.
Tools to Access the Latest Cancer Statistics Paul Miller Washington Reporting Fellowships program presentation April 15, 2013.
Incorporating Multiple Evidence Sources for the Assessment of Breast Cancer Policies and Practices J. Jackson-Thompson, Gentry White, Missouri Cancer Registry,
Epidemiology of HIV Among Hispanics Reported in Florida, Through 2013 Florida Department of Health HIV/AIDS Section Division of Disease Control and Health.
Healthy People 2010 Focus Area 3 Cancer Progress Review October 16, 2002.
Syphilis Sexually Transmitted Disease Surveillance 1999 Division of STD Prevention.
CANCER National Healthcare Quality and Disparities Report Chartbook on Effective Treatment.
STDs in Racial and Ethnic Minorities Sexually Transmitted Disease Surveillance 2010 Division of STD Prevention.
Focus Area 25 Sexually Transmitted Diseases Progress Review July 21, 2004.
Other Sexually Transmitted Diseases Sexually Transmitted Disease Surveillance 2009 Division of STD Prevention.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Division of Sexually Transmitted Disease Prevention.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Division of Sexually Transmitted Disease Prevention.
Healthy People 2010 Focus Area 2 Arthritis, Osteoporosis, and Chronic Back Conditions Progress Review July 20, 2006.
Housing Status and HIV Risk Behaviors Among Homeless and Housed Persons with HIV in the United States The findings and conclusions in this presentation.
The Geographic and Demographic Distribution of Melanoma Throughout the United States: Implications for Primary and Secondary Prevention Bertina Backus.
| Web: The findings and conclusions in this report are those of the authors and do not necessarily represent the official.
Collection of Cervical Carcinoma In Situ in Michigan NAACCR Conference San Diego – 2009 Glenn Copeland, Michigan Cancer Surveillance Program Meg Watson,
Assessing the Burden of HPV-Associated Cancers in the U.S., (ABHACUS): Monitoring the Impact of Emerging Technologies Using Cancer Registry Data.
Cervical cancer among Asian subgroups in California, Janet Bates, MD MPH California Cancer Registry NAACCR Annual Meeting Denver, Colorado June.
Mona Saraiya, MD, MPH National Immunization Conference March 7, 2006 Division of Cancer Prevention and Control National Center for Chronic Disease Prevention.
Cancers Linked to HPV Presenter: Chuck Lynch
Division of STD Prevention, CDC
Jun Li, MD MPH Epidemic Intelligence Service Officer
Cervical Cancer in California
Population-Based Cancer Registries in the United States:
Recent trends in cutaneous melanoma incidence and death rates in the United States,   Ahmedin Jemal, DVM, PhD, Mona Saraiya, MD, MPH, Pragna.
Nasreen Abdullah, MD, MPH
Kaposi Sarcoma Incidence Remains Unchanged Among African American Males In The Southern United States: U.S. Cancer Statistic Data, Donna L. White,
Focus on prostate cancer
Colorectal Cancer: National and International Perspective on the Burden of Disease and Public Health Impact  Ziad F. Gellad, Dawn Provenzale  Gastroenterology 
Peng-jun Lu, MD, PhD1; Mei-Chun Hung, MPH, PhD1,2 ; Alissa C
Learning Collaborative #6 October 2016
and total thyroid cancer mortality (USA) from 1993 to 2012
Recent trends in cutaneous melanoma incidence and death rates in the United States,   Ahmedin Jemal, DVM, PhD, Mona Saraiya, MD, MPH, Pragna.
M Javanbakht, S Guerry, LV Smith, P Kerndt
Melanoma surveillance in the United States: Overview of methods
U.S. Cancer Statistics Public Use Database Annual percent change of screening-amenable cancers by state, United States, I’m presenting today.
Cervical Cancer Surveillance, Screening, and Treatment
Trends in survival from metastatic lung cancer in California,
Measuring Health Disparities in Healthy People 2010
Focus on prostate cancer
Presentation transcript:

Meg Watson, MPH Recent Trends in HPV-Associated Cancers among Women Epidemiology and Applied Research Branch Division of Cancer Prevention and Control National Center Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention, Atlanta, GA.

Background: HPV-associated cancer  Human papillomavirus (HPV) associated with several cancers: Cervical Vaginal Vulvar Penile Anal Certain oral cavity/oropharyngeal sites

Background  Changes in screening and prevention HPV vaccine HPV DNA test Extended screening intervals  Current guidelines successful for cervical cancer; other HPV-associated cancers rare  Monitoring impact of future changes is important National need for surveillance to document vaccine impact Cancer registries uniquely positioned

Cervical cancer ages Cervical cancer ages Source: Chesson & Markowitz, International Society for Sexually Transmitted Diseases Research, London, 2009 Background: Estimated reduction in cervical cancer after onset of HPV vaccination program

Background: Rates of HPV-Associated Cancers among Women, Adapted from Watson et al. Using population-based cancer registry data to assess the burden of human papillomavirus-associated cancers in the United States: Overview of methods. Cancer,113:10;

Background: Trends in HPV-associated cancers, Adapted from Gillison, Chaturvedi, and Lowy. HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women. SiteAPC Cervix-2.3 Vulva0.4 Vagina-1.3 Anus (includes males)2.3 Oropharynx (includes males)0.5

Cancer registries included in our analysis, NPCR/SEER NPCR SEER NPCR/SEER PUERTO RICO ALASKA Atlanta Detroit San Francisco/ Oakland Los Angeles San Jose/ Monterey Seattle/ Puget Sound NM UT IA CA LA KY * National Program of Cancer Registries (CDC) † Surveillance, Epidemiology, and End Results Program (NCI) * † NJ CT PACIFIC ISLAND JURISDICTION HAWAII Excluded from analysis

Methods  NPCR and SEER incidence data, % of the U.S. population Invasive cancers only  Race/ethnicity Race: white, black, Asian-Pacific Islander (API), American Indian/Alaska Native (AI/AN) Ethnicity: Hispanic  Annual percent change (APC) Weighted least squares Statistical significance based on APC different from zero (p<0.05)

Methods: Defining HPV-associated cancers SiteICD-O-3 Histology code Cervix Carcinomas , Vulva Vagina Anus (including rectal SCCs) Oral cavity and oropharynx:  Base of Tongue and Lingual Tonsil  Tonsil (including Waldeyer ring)  Other oropharynx, potentially HPV-associated Squamous cell carcinomas (SCCs) ,

Results

Trends in HPV-associated cancers among US women, * Denotes statistical significance based on APC different from zero (p<0.05)

Trends in HPV-associated cancers among US women, NPCR/SEER, (excluding cervical, for larger scale) * Denotes statistical significance based on APC different from zero (p<0.05)

Trends in cervical cancer by race/ethnicity, NPCR/SEER, * Denotes statistical significance based on APC different from zero (p<0.05)

Trends in vulvar SCC by race/ethnicity, NPCR/SEER, * Denotes statistical significance based on APC different from zero (p<0.05)

Trends in anal SCC among women by race/ethnicity, NPCR/SEER, * Denotes statistical significance based on APC different from zero (p<0.05)

Trends in oral cavity/oropharyngeal SCC among women by race/ethnicity, NPCR/SEER, * Denotes statistical significance based on APC different from zero (p<0.05)

Summary and discussion of results Site Overall trend By race/ethnicity CervixAll races/ethnicities Vulva = Black women only Vagina = Black women only AnusBlack and white women OP/OC = No trends statistically significant = overall trend stable

Strengths and Limitations  Large population coverage  Ability to examine trends by race/ethnicity of rare cancers  Important in the context of vaccine and screening changes  Potential mis- classification of HPV status  Unknown co-factors such as smoking  Inconsistent reporting of some precancers known to be strongly HPV- associated

Conclusions  Cervical screening programs continue to be effective  Despite common risk factor (HPV), cancers vary by site  Changes evident in some HPV-associated cancers among women, prior to the vaccine  These changes should be taken into account in future efforts to monitor the potential impact of the HPV vaccine on these cancers.

 Co-authors: Mona Saraiya, Hannah Weir, Cheryll Thomas  Deblina Datta  The findings and conclusions in this presentation are those of the presenter, and do not necessarily represent the official position of the Centers for Disease Control and Prevention.  Contact: Acknowledgements