SRP Progress in Research Webinar March 21 st, 2016 Transforming Sustainability

Development of a High Performance Bioprocess for Eliminating 1,4-Dioxane in Water Fatemeh Shirazi, PhD Chief Executive Officer

Paints Resins Plastics Industrial cleaning Adhesives Artificial Leather Laboratory solvents Varnishes Waxes Pesticides Pharmaceuticals and Personal Care Products Cement 3 Sources and uses of 1,4-dioxane

Microvi has developed the world’s first biological process for treating 1,4-dioxane with 35%-55% lower total costs than conventional chemical or UV oxidation technologies. 4 Polluted Water Clean Water

Innovation & Technology Specifications  High performance continuous bioreactor for the aerobic degradation of 1,4-dioxane in water to less than 5 parts-per-billion.  Two Primary Innovations:  Novel synthetic biocatalyst composites  Novel monoculture for direct oxidation of 1,4-dioxane Novel Biocatalyst Composite  Simultaneous treatment of 1,4-dioxane and co-contaminants such as chlorinated solvents.  Hydraulic retention time (HRT) of 2-6 hours.  Single-pass treatment unit with no secondary waste stream. 5 Microvi’s MB-DX demonstration in San Jose, CA Novel Monoculture

6 Microvi’s MB-DX demonstration in San Jose, CA Dr. Farhad Dorri manually adjusting pilot settings

Technical Advantages 7

Technology Applications Drinking Water Industrial Waste Sites Superfund Sites 8 Point-of-Use Wastewater Treatment Landfills

Credits and References  Supported by NIH grant R44ES  Shirazi et. al. ”Ex-situ bioprocess for the treatment of groundwater containing 1,4-dioxane.” (In Process). 9 Microvi personnel involved in the MB-DX technology demonstration (left to right): Nik Hlavacek, Allison Gregg, Casey McGrath, Dr. Fatemeh Shirazi, Karen Palizzolo, Ali Dorri, Ameen Razavi. Not pictured: Dr. Joseph Salanitro, Dr. Farhad Dorri  Patent pending.  Special thanks to the Superfund Research Program, Ensafe, Inc., United Technologies Corporation (UTC), Intuitech, Inc., Dr. Thomas Mohr, McCampbell Analytical, Inc., and MWH Global, Inc.

Thank You! Contact Information: Phone: Web: Transforming Sustainability