SCIENTIFIC AND TECHNICAL CENTER "LEMT" BELOMO MINSK, BELARUS Laser medical apparatus STC "LEMT" BELOMO and biophysical foundations use MINSK, BELARUS JUNE 2011

Laser medical apparatus STC "LEMT" BELOMO

Biophysical foundations use of Laser medical apparatus LaserEr:YAGCO 2 Ho:YAGNd:YAG Diode laser Wavelength,µm2,9410,62,091,441,321,06 0,81- 0,98 Absorption depth,mm 0,0020,020,10,151, Table 1

Radiation wavelength(670±10) nm Mode of operationContinuous Maximal output power of radiation: in the aiming mode 3 mW in the working mode adjustable, from 0.1 to 2.5 W with the step of 0.1 W Instability of radiation power not more than 20 % Exposure time adjustable, from 1 second to 59 minutes 59 seconds Power supply(220±22)V, (50/60) Hz Consumed powerNot more than 100 Wт Time of preparing the device for operation Not more than 10 min Time of setting the working mode Not more than 1 min Overall dimensions of the laser block 280x270x160 mm Weight10 kg Average lifetimenot less than 5 years Average mean time to failurenot less than 800 hours SPECIFICATION UPL-PDT Apparatus for Photodynamic Therapy Photodynamic therapy is one of the rapidly developing sections of laser medicine. It is being applied not only in oncology (currently this is the main direction), but also in surgery (antibacterial photodynamic therapy), ophthalmology, dermatology, otolaryngology and etc. Photolon photosensitizer has been developed and is being produced in the Republic of Belarus for laser radiation wavelength of 670 nm at which UPL-FDT Apparatus operates.

UPL-3.0 Laser Apparatus for Ophthalmology UPL-3.0 laser semiconductor apparatus is designed for treatment eye grounds and ciliary body pathologies Moderate cost and simplicity in operation allow to use it in hospitals as well in polyclinics of regional, municipal and district level. Application of UPL-3.0 in vitreoretinalis surgery enables to solve the following problems: 1) Reduction of area that suffers from hypoxia of retina at proliferative diabetic rhinopathy, uveitis, retinovasculitis 2) Creation of chorioretinal commissure by perimeter of retina disruption, at retinotomia by its edge and around impacted into membrane intraocular of foreign body 3) Coagulation of intraocular tumors 4) Destruction of ciliary processes at neovascular and other types of slow-running glaucomas SPECIFICATION Radiation wavelength – 810±10 nm Power of laser radiation on the output – adjustable in the range from 0.1 to 3.0 W with the step of 0.01 Instability of laser radiation power – not more than 20% Duration of radiation pulse – from 0.01 to 9.99 seconds with the step of 0.01 in continuous mode Radiation wavelength of the aiming channel – 670 nm Operation mode – continuous Power supply – 220 V / 50 Hz

Diolas-810 Apparatus  Distinctive features of the new range of semiconductor surgical lasers are: portability at high output power; possibility of installation to operation console or cabinet; high reliability; possibility of operation in several modes; more economic in power consumption; relatively small cost.  New versions of apparatus include requests from doctors who used to work and continue working with them in patient care institutions and in private medical centers.  Diolas-810 Apparatus allows to perform almost blooldless dissection of tissues, especially of hollow organs, and to provide dosed and minimal thermal impact on pathologic focus and on tissues that surround it.  The apparatus is designed for performing operation procedures in various fields of surgery and dermatology, hemostasis in emergency, endoscopic, laparoscopic and “open” surgery, as well as in photo-destruction of benign and malignant new growths of skin and mucous. SPECIFICATION Radiation wavelength – 810±10 nm Power of the aiming laser, λ=532 nm (green beam) – 2 mW Power of laser radiation on the lightguide’s output – adjustable from 1 to 35 W Operation mode – pulse, continuous, pulse- periodical Duration of radiation pulse – from 10 to 1000 ms Means of radiation transmission – lightguide; diameter 0.4 mm; length 2500 mm Consumed power – 120 W Repetition rate of pulses – from 0.5 to 100 Hz Continuous runtime – 6 hours Power supply – 220 V / 50 Hz Overall dimensions – 420х 480х220 mm Weight – up to 25 kg

Diolas-940 Apparatus  Distinctive features of the new range of semiconductor surgical lasers are: portability at high output power which can be compared with solid-state lasers; possibility of installation to operation console or cabinet; high reliability; possibility of operation in several modes; more economic in power consumption; relatively small cost.  New versions of apparatus include requests from doctors who used to work and continue working with them in patient care institutions and in private medical centers.  Diolas-940 Apparatus is designed for performing surgical procedures in various fields of surgery, including treatment of varicose veins, vascular surgery, neurosurgery, otolaryngology, hemostasis in emergency, endoscopic and “open” surgery, as well as from photocoagulation of vascular pathologies of skin and mucous.  The apparatus can be applied in surgical departments of various profiles.  Features:  1) Steady hemostasis from small-diameter vessels  2) Can be used for intravenous coagulation during operations on varicose veins of feet.  3) Enables to perform through-skin photocoagulation of telangiectasia with minimal thermal damage of skin and treatment of particular forms of hemangioms and some other vascular affections of skin. SPECIFICATION Radiation wavelength – 940±10 nm Power of the aiming laser, λ=532 nm (green beam) – 2 mW Power of laser radiation on the lightguide’s output – adjustable from 1 to 35 W Operation mode – pulse, continuous, pulse-periodical Duration of radiation pulse – from 10 to 1000 ms Means of radiation transmission – lightguide; diameter 0.4 mm; length 2500 mm Consumed power – 120 W Repetition rate of pulses – from 0.5 to 100 Hz Continuous runtime – 6 hours Power supply – 220 V / 50 Hz Overall dimensions – 420х 480х220 mm Weight – up to 25 kg

The use of Diolas-940 Apparatus in otolaryngology

«Pulsar» Laser Surgical Apparatus  Device "Pulsar", based on Nd: YAG solid-state laser with lamp pumping, is a versatile laser surgical device. Management apparatus is carried out with a panel of computer stations with touch screen. Office of the wavelength provides adjustment of the depth of laser radiation on biological tissue within 0, mm. Adjusting of the pulse energy provides compensation of the loss of radiation on reflection and parasitic scattering to different layers and structural elements of tissue. Adjusting the duration and repetition rate of provides the minimum zone termonekroza for tissues with different times of thermal relaxation. The basic program is designed to use the device in the modes corresponding to the five groups of surgeries: skin, endoscopic, laparoscopic, in otorhinolaryngology and purulent surgery. In operation, the device is carried out automatically logging operations, saving modes. The database is designed for 1000 patients with the ability to transfer information to other carriers and the wireless network.   SPECIFICATION  Radiation wavelengths – 1.06 µm, 1.32 µm (0,947 µm, 1.44 µm)  Mode of radiation – pulse  Range of change of pulse-repetition rate – 1…100 Hz  Range of change of energy per pulse – 0.1…5 J  Duration of radiation pulse – 0, ms  Means of radiation transmission – monofiber quartz  lightguide; diameter 0.6 mm; length 2500 mm  Average radiation power – from 0.1 to 100 W  Presence of the aiming laser – diode laser with  the wavelength of 532 nm (green beam)  Cooling system – air-liquid  Power supply – 220 V / 50 Hz, 2,5 kW  Overall dimensions – 400 х 660 х 990 mm  Weight – 65 kg

Control window on the touch screen of Panel computer station ( examples )

Optima Laser Dentistry Apparatus Optima Laser Dentistry Apparatus is the first three-wave laser in the Republic of Belarus. The apparatus can also be used as a surgical laser of wide profile (neodymium channel with the wavelength of 1064 nm and 1320 nm). Laser technologies are being widely applied in all the sections of dentistry. In maxillofacial surgery they allow to perform a wide range of operations in oral cavity, enabling bloodless interventions, bactericidal effect, accelerated healing of wounds, minimal edema of tissues and almost total absence feelings of pain in postoperative period. Usage of erbium laser radiation has gained special effectiveness for treatment caries, dental deposits, alignment of teeth, dissection and sterilization of dental channels, treatment of teeth cavities in implantatology and etc. The main advantage of laser application in treatment of teeth pathologies is the effect of sterilization that allows to accelerate the process of filling cavities, and absence of vibrations that reduces pain significantly. The apparatus has passed medical trials in patient care institutions of the Republic of Belarus and in departments of the Belarusian State Medical University and the Belarusian Medical Academy of Post-diploma Education. SPECIFICATION Channel (1) Radiation wavelength 1064 nm 1320 nm Range of repetition frequency 1…50 Hz Range of pulse energy change 50…700 mJ 50…500 mJ Maximal pulse duration 150…300 mcs Means of radiation transmission to the working zone – quartz lightguide Maximal average radiation power on the output 30 W 20 W Channel (2) Radiation wavelength 2940 nm Range of repetition frequency 1…50 Hz Range of pulse energy change 50…300 mJ Maximal pulse duration 150…300 mcs Means of radiation transmission to the working zone – sapphire fiber Maximal average radiation power on the output – 4.0 W Cooling system – air-liquid Power supply – 220 V / 50 Hz, 3,5 kW Overall dimensions – 600x325x940 mm Weight –100 kg

PUBLICATIONS 1. Лазерные медицинские аппараты нового поколения / Д. А. Лукашенко, П. Н. Назаренко, В. В. Таранов и др.// Сборник докладов XXXIV Меж. научно - практ. конференции " Применение лазеров в медицине и биологии : фотодинамическая терапия ", Ялта, Крым АР, октября 2010 г.// Харьков, 2010, стр  2. Лазерный аппарат " Пульсар " и биофизические основы его применения / Д. А. Лукашенко, И. Г. Ляндрес, П. Н. Назаренко и др.// Электроника и связь. 5 Тематический выпуск " Электроника и нанотехнологии ", стр  3. Ляндрес И. Г., Назаренко П. Н., Шкадаревич А. П. Модернизированный лазерный хирургический аппарат " Пульсар "// Материалы научно - практической конференции с международным участием " Лазерная медицина ХХ I века ". - Москва, с Ляндрес И. Г., Назаренко П. Н., Таранов В. В., Хохленков Л. Н., Шкадаревич А. П. Лазерные хирургические аппараты " Пульсар " и " Диолаз " и возможности их применения в хирургии // Электроника и связь ч.2, с Трехволновая лазерная стоматологическая установка " Оптима ". Новые перспективы в стоматологии / Горшунов С. П., Ляндрес И. Г., П. Н. Назаренко, и др. // Материалы ХХШ Международной научно - практической конференции " Применение лазеров в медицине и биологии. - Николаев, с  6. Научно - технический отчет по заданию ГНТП " Медицинская техника ": Разработать и изготовить лазерную стоматологическую установку, освоить серийное производство, шифр " Оптима " ( заключ ) / Минпром РБ, РУП « ЛЭМТ »; ГР Минск, с. 1. Laser medical devices a new generation / DA Lukashenko, PN Nazarenko, VV Taranov, et al Proceedings of the International XXXIV. Scientific prakt.konferentsii "Application of Lasers in Medicine and Biology: photodynamic therapy", Yalta, Crimea Autonomous Republic, 6 - Oct. 10, 2010 / / Kharkov, 2010, p Laser device "Pulsar" and biophysical basis its applications, D. A. Lukashenko, IG Lyandres, PN Nazarenko et al / / Electronics and Communications. 5 thematic issue of "Electronics and Nanotechnology, p Lyandres IG, Nazarenko PN, Shkadarevich AP Upgraded laser surgical device "Pulsar" Proceedings of the scientific and practical conference with international participation "Laser Medicine of the XXI century". - Moscow, P Lyandres IG, Nazarenko PN, Taranov VV, Hohlenkov LN Shkadarevich AP Laser surgical apparatus "Pulsar" and "Diolaz and their possible applications in surgery / / Electronics and Communications Part 2, p Three-wave laser dental unit "Optima". New perspectives in dentistry / Gorshunov SP, Lyandres IG, PN Nazarenko, et al: Proceedings of XXIII International scientific-practical conference "Application of lasers in medicine and biology. - Nikolaev, p Scientific and technical report on orders Program "Medical Technology: Develop and manufacture laser dentistry installation, master batch production code "Optima" (signed) / Ministry of Industry of Belarus, RUE LEMT “, GR Minsk, – p.72.