MBV2010 Colloquium, February 25
RULES Multiple choice Only one correct answer seconds to answer No textbook, computer, mobile phone, please There will be a prize for the group with the most correct answers.
Example (does not count): What is astraphobia ? A Fear of lightning B Fear of spiders C Fear of heights D Fear of snakes 0
What is astraphobia ? 0
Which of the following systems repairs DNA mismatches? A RecBCD B MutSLH C UvrABC D DNA glycosylases 1
Which of the following systems repairs DNA mismatches? 1
What is shown in this figure? A histone modifications in telomeres B histone modifications in protein-coding genes C replacement of histone H3 in centromeres D replacement of histone H2A 2
What is shown in this figure? 2
What is the role of the SeqA protein in E. coli ? 3 A initiate replication B prevent replication C break hydrogen bonds D relieve topological stress in DNA
What is the role of the SeqA protein in E. coli ? 3 SeqA SeqA binds to hemimethylated DNA CH 3
When in a cell cycle is the eukaryotic origin recognition complex bound to DNA? 4 A in G 1, S, and G 2 B in S, G 2, and M C in G 2, M, and G 1 D only at the end of G 1
When in a cell cycle is the eukaryotic origin recognition complex bound to DNA? 4
Which of the following proteins is involved in initiation of replication in the nucleus? 5 A DnaA B Type II topoisomerases C Cdc6 D Cdc45
Which of the following proteins is involved in initiation of replication in the nucleus? 5
Replication protein A (RPA) is a 6 A helicase B topoisomerase C single-strand binding protein D DNA polymerase
Replication protein A (RPA) is a 6
The proliferating cell nuclear antigen (PCNA) is involved in 7 A cell division B nucleosome assembly C genome replication D formation of heterochromatin
The proliferating cell nuclear antigen (PCNA) is involved in 7
Which of the following DNA polymerases synthesizes DNA in a template-independent manner? A DNA polymerase I B DNA polymerase III C DNA polymerase IV D DNA polymerase ß 8
Which of the following DNA polymerases synthesizes DNA in a template-independent manner? 8
Which of the following sequences is complementary to 5’-AATGAA-3’ ? A 5’-TTACTT-3’ B 5’-AACTAA-3’ C 5’-TTCATT-3’ D 5’-AAGTAA-3’ 9
Which of the following sequences is complementary to 5’-AATGAA-3’ ? 9
Which proteins are shown in this figure? 10 A RuvA (1) and RuvB (2) B RuvA (2) and RuvB (1) C RuvA (1) and RuvC (2) D RuvB (1) and RuvC (2) 1 2
Which proteins are shown in this figure?
SWI/SNF is a A histone modification complex B nucleosome remodeling complex C nucleosome assembly complex D none of the above 11
SWI/SNF is a 11
Which of the following proteins resolves Holliday junctions? A RuvA B RuvB C RecA D RuvC 12
Which of the following proteins resolves Holliday junctions? 12 RuvC
The yellow protein in this figure is 13 A a DNA topoisomerase B a DNA polymerase C a DNA helicase D a primase
The yellow protein in this figure is 13