Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Bileaflet mechanical heart valve model Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Enlargement of jet region Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Horizontal mock circulatory loop Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Details of the acrylic valve model Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Typical loading rates during valve closure. Symbols represent the closure time of each leaflet. (Open=leaflet proximal to pressure transducer; solid=distal leaflet). Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Typical pressure wave forms (P2) measured ∼ 2mm downstream of the leaflet surface. Symbols represent the closure time of each leaflet. Open=leaflet proximal to pressure transducer; solid=distal leaflet. Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Comparison of the predicted minimum pressure to experiment at a low flow condition Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Comparison of the predicted minimum pressure to experiment at a high flow condition Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Comparison of the predicted closing time to experiment Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Comparison of the predicted minimum pressure (P2) to experiment Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Comparison of the predicted angular position to experiment Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Predicted angular rates at closure match experimental trends Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Predicted minimum pressure is significantly affected by a change in initial or final conditions for a constant dP∕dt=200mmHg∕s Figure Legend:

Date of download: 6/23/2016 Copyright © ASME. All rights reserved. From: Lumped Parameter Model for Computing the Minimum Pressure During Mechanical Heart Valve Closure J Biomech Eng. 2005;127(4): doi: / Simulation suggests that cavitation inception trends developed using the loading rate are likely to produce inconsistent results due to the variability in initial or final conditions and waveform shape. Solid=simulation; open=experimental. Figure Legend: