Uzhhorod National University. Uzhhorod National University, Ukraine EU Framework Programme for Research and Innovation "Horizon 2020" CBC program "Hungary-

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Uzhhorod National University

Uzhhorod National University, Ukraine EU Framework Programme for Research and Innovation "Horizon 2020" CBC program "Hungary- Slovakia-Romania-Ukraine" CBC program "Romania- Ukraine"

Uzhhorod National University Aim of the project: Development of a personalized diet approach for the prevention and treatment of diabetes type 2 and other chronic non-communicative diseases relevant to inflammation

Uzhhorod National University Objectives: 1)To develop the algorithm of prevention and treatment of non- communicable diseases based on obtained data about effect of edible plant originated foods rich in biologically active substances on mouth / intestinal miсrobiomе, local immune response and lipid metabolism (in diabetes type 2 case); 2) To establishing methodology based on that algorithm for implementation of personilased diet approach to maintain metabolic balance via individual human microbiome; 3) pre-clinical studies, 4) Clinical trial of effect of a personalized diet on intestinal miсrobiomе, local immune response and lipids metabolism of human to diabetes type 2; 5) Creation of the Food composition database in Ukraine; developing the “diet based tool” of prevention and new treatment of non-communicable diseases

Uzhhorod National University Main expected results of the project: Decreasing the average of non-communicable diseases in EU and strategic regions) Known mechanisms of regulation by diet based on plants the human miсrobiomе Implementation of algorithm of prevention of non- communicable diseases into medical practice Introduction Food composition database as a potential tool for calculation of human metabolic balance Social impact based on prevalence of active and healthy population

Uzhhorod National University Main foreseen activities: Creating personalized diets; Innovative research which is based on the metabolic balance and individual human microbiome; For the first time in Ukraine we will create a database of Ukrainian food products that will be useful and help people monitor the quality of food.

Uzhhorod National University Estimated Total Budget ,00 EUR Estimated duration 36 months

Uzhhorod National University Neem Biotech Ltd Clinical-Microbiomics ApS EPMA Fraunhofer IIS, FIIS Сassovia Life Sciences

Uzhhorod National University Scientific Research & Educational Center of MM & IMM, UzNU Nadiya Boyko, director Tel.: Viktoriia Bati & Tamara Meleshko, contact persons