You will need to be able to identify and provide characteristics of the following microscope slides: Autolysis of the liver (cirrhosis) Tuberculosis (Ghon tubercle) Chronic gastritis Dissecting aneurysm Peptic ulcer Atherosclerosis Arteriosclerosis Lobar pneumonia Pulmonary emphysema Lung cancer Myocardial infarction Melanoma Diverticulosis Thrombus Diabetic Pancreas

Hyalinization of islet cells

Diverticulosis Small herniations (pouches) form in the gastrointestinal tract The mucosa (lining of the intestine) becomes thickened with epithelium cells

Aneurysm Fresh: Point of dissection Healed: Scar tissue

Autolysis of the Liver Disorganized intercellular material Granular appearance of cytoplasm Orange-peel look White spots within the cytoplasm Fat Clumping of nuclear material

Hint:

Atherosclerosis Foam cells Made up of lipids Cholesterol clefts

Lung Cancer Large nuclei Nuclear clumping Multiple nuclei Abnormal organelles Tar may be present

Thrombus Blood clot that occludes vessel Made up of platelets, clotting factors, red blood cells, white blood cells, fibers

Arteriosclerosis Calcium deposits in the tunica media and atheroma The calcium interrupts the elastic fibers of the media

Myocardial Infarction Cardiac cells have lost their striations Cytoplasm has shrunk creating space between cells Nuclei are no longer present White blood cells have moved into the area

Chronic Gastritis Intestinal metaplasia occurs (parietal cells and chief cells degenerate) Goblet cells are apparent White blood cells appear

Tuberculosis Ghon tubercle present Necrosed center (possibly calcified) Fibrous cap on the tubercle

Hint Slide

Pneumonia Alveoli are congested with white blood cells Fluid fills some of the alveoli

Emphysema Alveoli are extremely large Some alveoli are broken No white blood cells present

Melanoma Large nuclei Nuclear clumping Multiple nuclei Abnormal organelles Occurs in the melanocytes

Peptic Ulcer Erosion of normal tissue White blood cells present