The Cochrane Library

The Cochrane Collaboration is named in honor of Archie Cochrane, a British medical researcher who contributed to the development of epidemiology as a science. A collection of databases that include high quality, independent, reliable evidence from Cochrane and other systematic reviews, clinical trials and more. Brings together research on the effectiveness of healthcare treatments and interventions from around the world. Based on the practice of evidence-based medicine Used by clinicians, policy makers, researchers, educators, students, patients and others. What is the Cochrane Library?

Who develops the Cochrane Library? The Cochrane Library is published by Wiley for The Cochrane Collaboration. The Cochrane Collaboration is an international not-for-profit organization: Aim: to help people make well-informed decisions about health care. How: by preparing, maintaining and promoting the accessibility of systematic reviews on the effects of healthcare interventions. Member groups of The Cochrane Collaboration include: Collaborative Review Groups (53) maintain and update Cochrane Reviews. Cochrane Centres (14) support people in their geographic and linguistic area. Fields (14) bring together healthcare issues impacting across review groups. Method Groups (13) develop the methodology of Cochrane Reviews. Consumer Network represents the interests of healthcare consumers.

Regional Cochrane Centre 1.Australasian Cochrane Centre8.Iberoamerican Cochrane Centre 2.Brazilian Cochrane Centre9.Italian Cochrane Centre 3.Canadian Cochrane Centre10.Nordic Cochrane Centre 4.Chinese Cochrane Centre11.South African Cochrane Centre 5.Dutch Cochrane Centre12.South Asian Cochrane Centre 6.French Cochrane Centre13.U.K Cochrane Centre 7.German Cochrane Centre14.U.S Cochrane Centre

What can you do with The Cochrane Library? Use: For improved patient care and outcomes. Based on the best available evidence which have been proven in practice. Research: The Cochrane Library has an Impact Factor of giving you confidence in quality and relevance. (2009 JCR) Provide feedback: Did it work for you? Do you have information relevant to the review? Contribute: Do you want to be a reviewer? Is there an issue you believe should be reviewed? Click the “Work with us” link at

The Cochrane Library databases 1. The Cochrane Database of Systematic Reviews (Cochrane Reviews) A systematic review investigates the effectiveness of interventions for prevention, treatment and rehabilitation in health care. Now includes reviews of diagnostic test accuracy studies. Now updated monthly! 2. The Database of Abstracts of Reviews of Effects (Other reviews) Complements Cochrane Reviews by quality-assessing and summarising reviews which have not been carried out by The Cochrane Collaboration.

The Cochrane Library databases 3. The Cochrane Central Register of Controlled Trials (Clinical trials) Includes details of published articles taken from bibliographic databases – such as MEDLINE and EMBASE - and other published sources. 580,000 reports of RCTs and other controlled trials 330,000 from MEDLINE [all records indexed as RCT or CCT in PT in humans] 90,000 additional reports of trials from searching EMBASE 160,000 reports of trials from hand searching journals / conference abstracts ) 4. Health Technology Assessment Database (Technology Assessments) Brings together details of completed and ongoing health technology assessments from around the world.

The Cochrane Library databases 5. The Cochrane Methodology Register (Methods Studies) Presents a bibliography of publications that report on methods used when conducting controlled trials. 6. NHS Economic Evaluation Database (Economic Evaluations) Systematically identifies economic evaluations of healthcare interventions from around the world, appraises their quality and highlights their relative strengths and weaknesses.

Number of included protocols and reviews As of Issue 4, 2011, the CDSR includes 6,602 articles: 4,594 reviews; and 2,008 protocols. Issue 4, 2011 includes 19 new reviews, 37 updated reviews (31 with a new search and 6 with changed conclusions). 31 new protocols and 1 updated protocol. 13 withdrawn reviews and protocols.

Number of published articles in the Cochrane Library DatabaseTotal published articles Cochrane Database of Systematic Reviews*6,602 Database of Abstracts of Reviews of Effects14,602 Cochrane Central Register of Controlled Trials645,068 Cochrane Methodology Register14,604 Health Technology Assessment Database9,965 NHS Economic Evaluation Database29,570 About The Cochrane Collaboration**81

What is a Systematic Review? A systematic review attempts to identify, appraise and synthesize all the empirical evidence that meets pre-specified eligibility criteria to answer a given research question. Researchers conducting systematic reviews use explicit methods aimed at minimizing bias, in order to produce more reliable findings that can be used to inform decision making

Step of Systematic Review Search of personal files Search of personal files Computerized Databases Computerized Databases Consultation with experts Consultation with experts Identify studies Relevant Evaluate methodological quality Evaluate methodological quality Extract data Analyze data Draw Conclusions Question Systematic manual searches of key journals Systematic manual searches of key journals Review of reference lists of articles Review of reference lists of articles Review for relevance Review for relevance Not Relevant Not Relevant Reject

2010 Top 5 Reviews - full-text Top 50 abstracts : Review Title Rank World -full text accesses Interventions for preventing falls in older people living in the community1 Interventions for preventing obesity in children2 Interventions for preventing falls in older people in nursing care facilities and hospitals3 Interventions for treating obesity in children4 Support surfaces for pressure ulcer prevention5

The Cochrane Database of Systematic Reviews The “gold standard” for systematic reviews Combines results of the world’s best medical research studies Adhere to a strict process to make them more comprehensive, thus minimizing bias and ensuring reliability Updated regularly - ensuring that treatment decisions can be based on the most up-to-date, reliable evidence.

Authoring team Expertise might include: Clinical knowledge Searching skills Relevant statistics Prepare protocol (3 months to one year) Register title Prepare review (one to five years) The Cochrane Library (CDSR and About updated monthly other databases updated quarterly) Publishing reviews in The Cochrane Library

The Cochrane Library homepage Browsing Searches (Advanced, MeSH Search) Viewing reviews and protocols Demonstrating the Cochrane Library

The Cochrane Library homepage

Browsing 토픽 별 Cochrane Systematic Reviews 브라우징 가능. 하단의 “expand” 를 클릭하면 전체 토픽 확인 가능. Trial 만 따로 브라우징 가능. CDSR 외의 데이터베이스 브라우징 가능. Other browse option 이용가능.

Advanced and MeSH searches Advanced Search 를 클릭해서 Advanced Search, MeSH Search, Search History, Saved Searches 이용 가능. 검색결과를 저장, 저장된 검색결과를 이용 혹은 alerts 를 설정하려면 Wiley Online Library 유저 등록을 해야 함. Key word 로 검색하거나

회원 가입 및 로그인 ID/PW 입력 후 로그인 아직 가입하지 않았다면 Register Now 를 클릭

*, “ ” 등의 기호 혹은 Boolean 연산자 (AND, OR, NOT) 를 사용하여 검색결과를 개선하거나 범위 확 대 Boolean 연산자는 textbox 에 직접입력 혹은 드롭다 운 후 선택 모두 가능 특정 필드 지정으로 검색 제한 가능 데이터베이스 및 레코드 상태 혹은 날짜 제한 Search tips…

원하는 다른 기준으로 다시 정렬하거나 다른 특정 영역을 선택해서 검색 결 과를 좀 더 풍부하게 할 수 있습니다. Edit Search 를 클릭해서 검색식을 편 집할 수 있습니다. 로그인 상태라면 검색쿼리를 저 장할 수 있습니다.

MeSH searches The Medical Subject Heading (MeSH) search is based on the National Library of Medicine's controlled vocabulary thesaurus of medical subject headings index. Recently published Cochrane reviews are NOT yet MeSH indexed. Combine MeSH and advanced searches to be sure of retrieving the most recent articles. DatabaseMeSH indexing Cochrane ReviewsFully indexed except for Reviews first published in recent issues Cochrane ProtocolsNo MeSH indexing Clinical TrialsOnly reviews taken from Medline Other ReviewsFully indexed Technology AssessmentsFully indexed Economic EvaluationsFully indexed

Snapshot of SR Main Page SR status icon

Full Review ( 메타 분석을 포함한 연구결과 및 토론을 조합 ) 리뷰의 준비 단계 ( 연구배경, 근거, 방법 등을 포함 ) Methodological study 에 대한 Systematic Review (Full-Text) Diagnostic test 의 정확성 평가에 대한 Systematic Review (Full-Text) 다양한 Cochrane Intervention Review 의 개요. 최근에 수록된 리뷰 또는 프로토콜 자료. 발표된 리뷰의 conclusion 에 중요한 변화가 발생한 경우. 기존에 발표된 리뷰에 대한 새로운 내용이 추가되었을 경우. 최근에 수록된 프로토콜이 수정된 경우. 리뷰 혹은 프로토콜이 연구 철회된 경우 ( 연구 철회의 이유에 대해 명시 ) Comment (Reader 의 feedback 과 저자의 답변 등 ) 가 달린 리뷰자료

TOC of Protocol vs SR

TOC 에서 Plain language summary, 연구 배경, 목적, 방법 및 결과 등 리뷰 및 프로토콜의 모든 항목으로 이동할 수 있습니다. PDF 를 다운로드 ( 풀버전 및 스탠다드 버전 선택 가능 ) 풀버젼은 완전한 모든 세부 사항을 포함하는 반면 스탠다드 버전은 데이터 및 분석 요약만 포함..

Feed back& Comment

Oods Ration Diagram

Citation 다운로드 연구과정의 support 명시 비의료인을 위한 평이한 해설 : 전문용어 배제 제약 회사 등 영리 기관 ( 단체 ) 의 지원이 있었다면 반드시 명시